Microsporidiosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ogheneochuko Ajari, MB.BS, MS [2];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [3]

Overview

Symptoms of intestinal microsporidiosis include chronic diarrhea, abdominal pain, and weight loss.

History and Symptoms

Microsporidiosis can affect many systems. Intestinal microsporidiosis is the most common form of the disease.

Intestinal microsporidiosis:

In immunocompetent individuals

Intestinal microsporidiosis may be asymptomatic or causes transient diarrhea. In rare cases, it might cause chronic diarrhea.

In immunocompromised individuals

• Chronic diarrhea: nonbloody watery diarrhea
• Abdominal pain
• Weight loss
• May be associated with nausea and vomiting.

Disseminated disease

Eye involvement

Ocular involvement can cause keratitis which present with red eye, tearing, foreign body sensation

Musculoskeletal involvement

• Muscle pain
• Fever
• Muscle weakness

Central nervous system involvement

• Microsporidiosis may present with symptoms of space occupying lesions such as:
• Headache
• Seizures
• Projectile vomiting