Prolactinoma causes: Difference between revisions

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Revision as of 20:38, 19 July 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic.

Causes

There are no established causes for prolactinoma. Most cases of prolactinoma are sporadic. Prolactinoma may occur in approximately 30% of Multiple endocrine neoplasia type 1.It may also occur with Carney complex or McCune-Albright syndrome.^[1]

Common causes

Sporadic
Hereditary causes:
- Multiple endocrine neoplasia type 1 (MEN 1)

Less Common/Rare causes

Hereditary causes:
- A minority of prolactinoma are associated with:^[1]^[2]
  1. Carney complex
  2. McCune-Albright Syndrome
  3. Isolated familial pituitary adenoma

References

↑ ^1.0 ^1.1 Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.
↑ Karhu A, Aaltonen LA (2007). "Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update". Hum Mol Genet. 16 Spec No 1: R73–9. doi:10.1093/hmg/ddm036. PMID 17613551.

Template:WikiDoc Sources

[pmid16411062-1] 1.0 ^1.1 Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.

[pmid17613551-2] Karhu A, Aaltonen LA (2007). "Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update". Hum Mol Genet. 16 Spec No 1: R73–9. doi:10.1093/hmg/ddm036. PMID 17613551.

[1]

[2]

@@ Line 3: / Line 3: @@
 {{CMG}} {{AE}}{{Anmol}}
 ==Overview==
-There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are [[sporadic]].
+There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are sporadic.
 ==Causes==
-There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are [[sporadic]]. [[Prolactinoma]] may occur in approximately 30% of [[Multiple endocrine neoplasia type 1]].It may also occur with [[Carney complex]] or [[McCune-Albright syndrome]].<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref>
+There are no established causes for [[prolactinoma]]. Most cases of [[prolactinoma]] are sporadic. [[Prolactinoma]] may occur in approximately 30% of [[Multiple endocrine neoplasia type 1]].It may also occur with [[Carney complex]] or [[McCune-Albright syndrome]].<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref>
+===Common causes===
+*Sporadic
+*[[Hereditary]] causes:
+**[[Multiple endocrine neoplasia type 1]] ([[MEN 1]])
-===Familial Causes<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref><ref name="pmid17613551">{{cite journal| author=Karhu A, Aaltonen LA| title=Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. | journal=Hum Mol Genet | year= 2007 | volume= 16 Spec No 1 | issue=  | pages= R73-9 | pmid=17613551 | doi=10.1093/hmg/ddm036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17613551  }} </ref>===
+===Less Common/Rare causes===
+*[[Hereditary]] causes:
-[[Prolactinoma]] may occur as part of a [[hereditary disorder]] called [[multiple endocrine neoplasia type 1]] ([[MEN 1]]). A minority of [[prolactinoma]] are associated with:
+**A minority of [[prolactinoma]] are associated with:<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref><ref name="pmid17613551">{{cite journal| author=Karhu A, Aaltonen LA| title=Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. | journal=Hum Mol Genet | year= 2007 | volume= 16 Spec No 1 | issue=  | pages= R73-9 | pmid=17613551 | doi=10.1093/hmg/ddm036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17613551  }} </ref>
-*[[Carney complex]]
+**#[[Carney complex]]
-*[[McCune-Albright Syndrome]]
+**#[[McCune-Albright Syndrome]]
-*Isolated [[familial]] [[pituitary adenoma]]
+**#Isolated [[familial]] [[pituitary adenoma]]
-=== Other Causes ===
-Other causes include:
-*The xenoestrogenic chemical Bisphenol-A has been demonstrated to result in [[hyperprolactinaemia]] and growth of [[Lactotroph|prolactin-producing pituitary cells]].<ref>^ Goloubkova T, Ribeiro MF, Rodrigues LP, Cecconello AL, Spritzer PM (April 2000). "Effects of xenoestrogen bisphenol A on uterine and pituitary weight, serum prolactin levels and immunoreactive prolactin cells in ovariectomized Wistar rats". Arch. Toxicol. 74 (2): 92–8. doi:10.1007/s002040050658. PMID 10839476</ref> The increasing and prolonged exposure of Bisphenol-A from childhood may contribute to the development and growth of a [[prolactinoma]].
 == References ==