Growth hormone deficiency diagnostic criteria: Difference between revisions
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'''For patient information, click [[Growth hormone deficiency (patient information)|here]]''' | '''For patient information, click [[Growth hormone deficiency (patient information)|here]]''' | ||
==Overview== | ==Overview== | ||
*The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4]. | |||
*The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3]. | |||
*The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3]. | |||
OR | |||
*There are no established criteria for the diagnosis of [disease name]. | |||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
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Because of uncertainties and complexities of diagnosis and the high costs of treatment, diagnosis of growth hormone deficiency has been a more persistent subject of debate and controversy in clinical endocrinology than any other aspect of endocrine diagnosis. It has become a major type of internet fraud ([[HGH quackery]]). | Because of uncertainties and complexities of diagnosis and the high costs of treatment, diagnosis of growth hormone deficiency has been a more persistent subject of debate and controversy in clinical endocrinology than any other aspect of endocrine diagnosis. It has become a major type of internet fraud ([[HGH quackery]]). | ||
==Diagnostic Criteria== | |||
*The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: | |||
**[criterion 1] | |||
**[criterion 2] | |||
**[criterion 3] | |||
**[criterion 4] | |||
*The diagnosis of [disease name] is based on the [criteria name] criteria, which include | |||
**[criterion 1] | |||
**[criterion 2] | |||
**[criterion 3] | |||
*The diagnosis of [disease name] is based on the [definition name] definition, which includes | |||
**[criterion 1] | |||
**[criterion 2] | |||
**[criterion 3] | |||
OR | |||
*There are no established criteria for the diagnosis of [disease name]. | |||
==References== | ==References== | ||
{{ | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 17:49, 7 August 2017
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Differentiating Growth hormone deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] For patient information, click here
Overview
- The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
- The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
- The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
OR
- There are no established criteria for the diagnosis of [disease name].
Diagnostic Criteria
Several types of evidence are used to ascertain GH sufficiency or deficiency.
- Auxologic criteria (defined by body measurements)
- Indirect hormonal criteria (IGF levels from a single blood sample)
- Direct hormonal criteria (measurement of GH in multiple blood samples to determine secretory patterns or responses to provocative testing)
- Response to GH treatment
- Corroborative evidence of pituitary dysfunction
For GH deficiency, as for many other diseases, the practical purpose and effect of these diagnostic criteria is to determine who is to be treated with it. GH deficiency accounts for only a minority of short stature among children. GH deficiency accounts for an even smaller proportion of fatigability, excessive fat, osteopenic bones, and underdeveloped muscles in adults. An ideal diagnostic test cleanly separates people who would benefit from a treatment from those who would not. Unfortunately, none of the criteria listed above do so, not even in various combinations.
The common clinical problem is that many children and adults being evaluated meet some, but not all, of the above criteria. Since many children and adults who do not meet all of the diagnostic criteria may receive some of the benefits of treatment, small differences in the diagnostic criteria make large differences in the number of short or tired people diagnosed with deficiency.
Because of uncertainties and complexities of diagnosis and the high costs of treatment, diagnosis of growth hormone deficiency has been a more persistent subject of debate and controversy in clinical endocrinology than any other aspect of endocrine diagnosis. It has become a major type of internet fraud (HGH quackery).
Diagnostic Criteria
- The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
- [criterion 1]
- [criterion 2]
- [criterion 3]
- [criterion 4]
- The diagnosis of [disease name] is based on the [criteria name] criteria, which include
- [criterion 1]
- [criterion 2]
- [criterion 3]
- The diagnosis of [disease name] is based on the [definition name] definition, which includes
- [criterion 1]
- [criterion 2]
- [criterion 3]
OR
- There are no established criteria for the diagnosis of [disease name].