Protein energy malnutrition laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of protein energy malnutrition include abnormally low blood glucose, hypoalbuminemia (10-25 g/L), hypoproteinemia (transferrin, essential amino acids, lipoprotein)and hypoglycemia. | Laboratory findings consistent with the diagnosis of protein energy malnutrition include abnormally [[Hypoglycemia|low blood glucose]], [[hypoalbuminemia]] (10-25 g/L), [[hypoproteinemia]] ([[transferrin]], [[essential amino acids]], [[lipoprotein]])and [[hypoglycemia]]. | ||
==Laboratory findings== | ==Laboratory findings== | ||
Laboratory findings consistent with the diagnosis of protein energy malnutrition include: | Laboratory findings consistent with the diagnosis of protein energy malnutrition include: | ||
*Abnormally low blood glucose | *Abnormally [[Hypoglycemia|low blood glucose]] | ||
*Abnormal blood smears by microscopy or direct detection testing | *Abnormal [[Blood smear|blood smears]] by [[microscopy]] or direct detection testing | ||
*Decreased serum hemoglobin | *Decreased [[Hemoglobin|serum hemoglobin]] | ||
*Abnormal urinalysis and culture | *Abnormal [[urinalysis]] and [[Culture medium|culture]] | ||
Specific laboratory findings in patients with kwashiorkor include: | Specific laboratory findings in patients with [[kwashiorkor]] include: | ||
*Hypoalbuminemia (10-25 g/L) | *[[Hypoalbuminemia]] (10-25 g/L) | ||
*Hypoproteinemia (transferrin, essential amino acids, lipoprotein) | *[[Hypoproteinemia]] ([[transferrin]], [[essential amino acids]], [[lipoprotein]]) | ||
*Hypoglycemia | *[[Hypoglycemia]] | ||
*Elevated plasma cortisol and growth hormone levels | *Elevated [[Cortisol|plasma cortisol]] and [[growth hormone]] levels | ||
*Decreased insulin secretion and insulin-like growth factor | *Decreased [[insulin]] secretion and [[insulin-like growth factor]] | ||
*Increased percentage of body water and extracellular water | *Increased percentage of body water and extracellular water | ||
*Depletion of electrolytes, especially potassium and magnesium | *Depletion of [[Electrolyte|electrolytes]], especially [[potassium]] and [[magnesium]] | ||
*Decreased levels of some enzymes (including lactase) | *Decreased levels of some [[enzymes]] (including [[lactase]]) | ||
*Iron deficiency anemia and metabolic acidosis | *[[Iron deficiency anemia]] and [[metabolic acidosis]] | ||
Specific laboratory findings in patients with marasmus include: | Specific laboratory findings in patients with [[marasmus]] include: | ||
*Increased urinary 3-methylhistidine, a reflection of muscle breakdown | *Increased urinary 3-methylhistidine, a reflection of muscle breakdown | ||
*Urinary excretion of hydroxyproline is diminished, reflecting impaired growth and wound healing | *Urinary excretion of [[hydroxyproline]] is diminished, reflecting impaired growth and wound healing | ||
*Iron deficiency anemia | *[[Iron deficiency anemia]] | ||
*Metabolic acidosis | *[[Metabolic acidosis]] | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 13:31, 9 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of protein energy malnutrition include abnormally low blood glucose, hypoalbuminemia (10-25 g/L), hypoproteinemia (transferrin, essential amino acids, lipoprotein)and hypoglycemia.
Laboratory findings
Laboratory findings consistent with the diagnosis of protein energy malnutrition include:
- Abnormally low blood glucose
- Abnormal blood smears by microscopy or direct detection testing
- Decreased serum hemoglobin
- Abnormal urinalysis and culture
Specific laboratory findings in patients with kwashiorkor include:
- Hypoalbuminemia (10-25 g/L)
- Hypoproteinemia (transferrin, essential amino acids, lipoprotein)
- Hypoglycemia
- Elevated plasma cortisol and growth hormone levels
- Decreased insulin secretion and insulin-like growth factor
- Increased percentage of body water and extracellular water
- Depletion of electrolytes, especially potassium and magnesium
- Decreased levels of some enzymes (including lactase)
- Iron deficiency anemia and metabolic acidosis
Specific laboratory findings in patients with marasmus include:
- Increased urinary 3-methylhistidine, a reflection of muscle breakdown
- Urinary excretion of hydroxyproline is diminished, reflecting impaired growth and wound healing
- Iron deficiency anemia
- Metabolic acidosis