Hyperparathyroidism classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

Hyperparathyroidism can be classified into primary, secondary and tertiary.

Classification

Hyperparathyroidism can be classified into primary, secondary and tertiary.

Primary hyperparathyroidism

Primary hyperparathyroidism results from a hyperfunction of the parathyroid glands themselves. There is oversecretion of PTH due to adenoma, hyperplasia or, rarely, carcinoma of the parathyroid glands.

Secondary hyperparathyroidism

Secondary hyperparathyroidism is the reaction of the parathyroid glands to a hypocalcemia caused by other than a parathyroid pathology, e.g. chronic renal failure.

Tertiary hyperparathyroidism

Tertiary hyperparathyroidism is a state of excessive secretion of parathyroid hormone (PTH) after a long period of secondary hyperparathyroidism and resulting in hypercalcemia.

Hyperparathyroidism

Primary hyperparathyroidism

Secondary hyperparathyroidism

Tertiary hyperparathyroidosm

Parathyroid adenoma Parathyroid hyperplasia Parathyroid carcinoma

Chronic renal failure Vitamin D deficiency

Chronic renal failure