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==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually
 
===Case-fatality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate of [number range]%.
*The case-fatality rate of [disease name] is approximately [number range].
===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Cretinism affects the new borns.
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
===Race===
*There is no racial predilection to [disease name].
*Cretinism usually affects individuals of the Hispanic and Asian races more the white and black races.  
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
*The incidence of cretinism in the different races as the following: <ref name="pmid17512233" />
**Asian race: the incidence of cretinism is 98.4 per 100,000 Asian individuals.
**Hispanic race: the incidence of cretinism is 64.1 per 100,000 Asian individuals.
**White race: the incidence of cretinism is 55.1 per 100,000 white individuals.
**Black race: the incidence of cretinism is 52.6 per 100,000 black individuals.
===Gender===
===Gender===
*[Disease name] affects men and women equally.
*Females are more commonly affected by cretinism than males. The female to male ratio is approximately 2:1. <ref name="pmid15728201">{{cite journal| author=Eugène D, Djemli A, Van Vliet G| title=Sexual dimorphism of thyroid function in newborns with congenital hypothyroidism. | journal=J Clin Endocrinol Metab | year= 2005 | volume= 90 | issue= 5 | pages= 2696-700 | pmid=15728201 | doi=10.1210/jc.2004-2320 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15728201  }}</ref>
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
===Region===
*The majority of [disease name] cases are reported in [geographical region].
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
 
===Developed Countries===
===Developed Countries===
* The incidence of cretinism is estimated to be 31.5 per 100,000 individuals in the United States.<ref name="pmid17512233">{{cite journal| author=Harris KB, Pass KA| title=Increase in congenital hypothyroidism in New York State and in the United States. | journal=Mol Genet Metab | year= 2007 | volume= 91 | issue= 3 | pages= 268-77 | pmid=17512233 | doi=10.1016/j.ymgme.2007.03.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17512233  }}</ref>
* Between 1978 and 2005, the incidence of cretinism was estimated to be 48.3 cases per 100,000 individuals in the New York state.
* Between 1981 and 2002, the incidence of cretinism was estimated to be 25 cases per 100,000 individuals in France.<ref name="pmid15807875">{{cite journal| author=Gaudino R, Garel C, Czernichow P, Léger J| title=Proportion of various types of thyroid disorders among newborns with congenital hypothyroidism and normally located gland: a regional cohort study. | journal=Clin Endocrinol (Oxf) | year= 2005 | volume= 62 | issue= 4 | pages= 444-8 | pmid=15807875 | doi=10.1111/j.1365-2265.2005.02239.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15807875  }}</ref>


===Developing Countries===
===Developing Countries===
 
* Between 2006 and 2012, the incidence of cretinism was estimated to be 170 cases per 100,000 individuals in Iran.<ref name="pmid24932604">{{cite journal| author=Dorreh F, Chaijan PY, Javaheri J, Zeinalzadeh AH| title=Epidemiology of congenital hypothyroidism in Markazi Province, Iran. | journal=J Clin Res Pediatr Endocrinol | year= 2014 | volume= 6 | issue= 2 | pages= 105-10 | pmid=24932604 | doi=10.4274/Jcrpe.1287 | pmc=4141571 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24932604  }}</ref>
 


==References==
==References==

Revision as of 15:59, 15 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

Prevalence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
  • The prevalence of [disease/malignancy] is estimated to be [number] cases annually

Age

  • Cretinism affects the new borns.

Race

  • Cretinism usually affects individuals of the Hispanic and Asian races more the white and black races.
  • The incidence of cretinism in the different races as the following: [1]
    • Asian race: the incidence of cretinism is 98.4 per 100,000 Asian individuals.
    • Hispanic race: the incidence of cretinism is 64.1 per 100,000 Asian individuals.
    • White race: the incidence of cretinism is 55.1 per 100,000 white individuals.
    • Black race: the incidence of cretinism is 52.6 per 100,000 black individuals.

Gender

  • Females are more commonly affected by cretinism than males. The female to male ratio is approximately 2:1. [2]

Developed Countries

  • The incidence of cretinism is estimated to be 31.5 per 100,000 individuals in the United States.[1]
  • Between 1978 and 2005, the incidence of cretinism was estimated to be 48.3 cases per 100,000 individuals in the New York state.
  • Between 1981 and 2002, the incidence of cretinism was estimated to be 25 cases per 100,000 individuals in France.[3]

Developing Countries

  • Between 2006 and 2012, the incidence of cretinism was estimated to be 170 cases per 100,000 individuals in Iran.[4]

References

  1. 1.0 1.1 Harris KB, Pass KA (2007). "Increase in congenital hypothyroidism in New York State and in the United States". Mol Genet Metab. 91 (3): 268–77. doi:10.1016/j.ymgme.2007.03.012. PMID 17512233.
  2. Eugène D, Djemli A, Van Vliet G (2005). "Sexual dimorphism of thyroid function in newborns with congenital hypothyroidism". J Clin Endocrinol Metab. 90 (5): 2696–700. doi:10.1210/jc.2004-2320. PMID 15728201.
  3. Gaudino R, Garel C, Czernichow P, Léger J (2005). "Proportion of various types of thyroid disorders among newborns with congenital hypothyroidism and normally located gland: a regional cohort study". Clin Endocrinol (Oxf). 62 (4): 444–8. doi:10.1111/j.1365-2265.2005.02239.x. PMID 15807875.
  4. Dorreh F, Chaijan PY, Javaheri J, Zeinalzadeh AH (2014). "Epidemiology of congenital hypothyroidism in Markazi Province, Iran". J Clin Res Pediatr Endocrinol. 6 (2): 105–10. doi:10.4274/Jcrpe.1287. PMC 4141571. PMID 24932604.

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