Insulinoma diagnostic criteria: Difference between revisions
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*The classical diagnosis of insulinoma is based on the Whipple's triad(1935)<ref name="pmid17856569">{{cite journal |vauthors=Whipple AO, Frantz VK |title=ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW |journal=Ann. Surg. |volume=101 |issue=6 |pages=1299–335 |year=1935 |pmid=17856569 |pmc=1390871 |doi= |url=}}</ref>, which includes: | *The classical diagnosis of insulinoma is based on the Whipple's triad(1935)<ref name="pmid17856569">{{cite journal |vauthors=Whipple AO, Frantz VK |title=ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW |journal=Ann. Surg. |volume=101 |issue=6 |pages=1299–335 |year=1935 |pmid=17856569 |pmc=1390871 |doi= |url=}}</ref>, which includes: | ||
#Hypoglycemia( fasting blood glucose <50 mg/dL) | #Hypoglycemia( fasting blood glucose <50 mg/dL) | ||
#Symptoms of hypoglycemia | #Symptoms of hypoglycemia<ref name="pmid18703061">{{cite journal| author=Metz DC, Jensen RT| title=Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. | journal=Gastroenterology | year= 2008 | volume= 135 | issue= 5 | pages= 1469-92 | pmid=18703061 | doi=10.1053/j.gastro.2008.05.047 | pmc=2612755 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18703061 }} </ref> | ||
#*Neuroglycopenic- Blurring of vision, Diplopia | #*Neuroglycopenic- Blurring of vision, Diplopia | ||
#*Adrenergic-Sweating, palpitations | #*Adrenergic-Sweating, palpitations | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
OR
The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
OR
The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
OR
There are no established criteria for the diagnosis of [disease name].
Diagnostic Criteria
- The classical diagnosis of insulinoma is based on the Whipple's triad(1935)[1], which includes:
- Hypoglycemia( fasting blood glucose <50 mg/dL)
- Symptoms of hypoglycemia[2]
- Neuroglycopenic- Blurring of vision, Diplopia
- Adrenergic-Sweating, palpitations
- Improvement of symptoms after glucose infusion
- The diagnosis of insulinoma is based on the Biochemical assay which includes
- Insul
References
- ↑ Whipple AO, Frantz VK (1935). "ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW". Ann. Surg. 101 (6): 1299–335. PMC 1390871. PMID 17856569.
- ↑ Metz DC, Jensen RT (2008). "Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors". Gastroenterology. 135 (5): 1469–92. doi:10.1053/j.gastro.2008.05.047. PMC 2612755. PMID 18703061.