Insulinoma CT: Difference between revisions
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**atypically can appear hypovascular and [[hypodense]] lesions after the administration of contrast, as compared to [[hyperdense]] lesions before the administration; cystic masses, and [[calcified]] masses(in [[malignant]] lesions when they are [[nodular]] and discrete)<ref name="pmid16179163">{{cite journal| author=McAuley G, Delaney H, Colville J, Lyburn I, Worsley D, Govender P et al.| title=Multimodality preoperative imaging of pancreatic insulinomas. | journal=Clin Radiol | year= 2005 | volume= 60 | issue= 10 | pages= 1039-50 | pmid=16179163 | doi=10.1016/j.crad.2005.06.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16179163 }} </ref><ref name="pmid15763695">{{cite journal| author=Noone TC, Hosey J, Firat Z, Semelka RC| title=Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. | journal=Best Pract Res Clin Endocrinol Metab | year= 2005 | volume= 19 | issue= 2 | pages= 195-211 | pmid=15763695 | doi=10.1016/j.beem.2004.11.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15763695 }} </ref> | **atypically can appear hypovascular and [[hypodense]] lesions after the administration of contrast, as compared to [[hyperdense]] lesions before the administration; cystic masses, and [[calcified]] masses(in [[malignant]] lesions when they are [[nodular]] and discrete)<ref name="pmid16179163">{{cite journal| author=McAuley G, Delaney H, Colville J, Lyburn I, Worsley D, Govender P et al.| title=Multimodality preoperative imaging of pancreatic insulinomas. | journal=Clin Radiol | year= 2005 | volume= 60 | issue= 10 | pages= 1039-50 | pmid=16179163 | doi=10.1016/j.crad.2005.06.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16179163 }} </ref><ref name="pmid15763695">{{cite journal| author=Noone TC, Hosey J, Firat Z, Semelka RC| title=Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. | journal=Best Pract Res Clin Endocrinol Metab | year= 2005 | volume= 19 | issue= 2 | pages= 195-211 | pmid=15763695 | doi=10.1016/j.beem.2004.11.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15763695 }} </ref> | ||
* CT quality have been improved with techology advances with using dual-phase thin-section multdetector CT having senstivity of 94.4% as compared to 57 % for dual-phase multidetector without thin sections and 28.6% with sequential CT.<ref name="pmid16179163">{{cite journal| author=McAuley G, Delaney H, Colville J, Lyburn I, Worsley D, Govender P et al.| title=Multimodality preoperative imaging of pancreatic insulinomas. | journal=Clin Radiol | year= 2005 | volume= 60 | issue= 10 | pages= 1039-50 | pmid=16179163 | doi=10.1016/j.crad.2005.06.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16179163 }} </ref><ref name="pmid16498592">{{cite journal| author=Tucker ON, Crotty PL, Conlon KC| title=The management of insulinoma. | journal=Br J Surg | year= 2006 | volume= 93 | issue= 3 | pages= 264-75 | pmid=16498592 | doi=10.1002/bjs.5280 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16498592 }} </ref> | * CT quality have been improved with techology advances with using dual-phase thin-section multdetector CT having senstivity of 94.4% as compared to 57% for dual-phase multidetector without thin sections and 28.6% with sequential CT.<ref name="pmid16179163">{{cite journal| author=McAuley G, Delaney H, Colville J, Lyburn I, Worsley D, Govender P et al.| title=Multimodality preoperative imaging of pancreatic insulinomas. | journal=Clin Radiol | year= 2005 | volume= 60 | issue= 10 | pages= 1039-50 | pmid=16179163 | doi=10.1016/j.crad.2005.06.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16179163 }} </ref><ref name="pmid16498592">{{cite journal| author=Tucker ON, Crotty PL, Conlon KC| title=The management of insulinoma. | journal=Br J Surg | year= 2006 | volume= 93 | issue= 3 | pages= 264-75 | pmid=16498592 | doi=10.1002/bjs.5280 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16498592 }} </ref> | ||
==References== | ==References== |
Revision as of 20:42, 22 August 2017
Insulinoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Insulinoma CT On the Web |
American Roentgen Ray Society Images of Insulinoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
There are no CT scan findings associated with [disease name].
OR
[Location] CT scan may be helpful in the diagnosis of [disease name]. Findings on CT scan suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
OR
There are no CT scan findings associated with [disease name]. However, a CT scan may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].
CT scan
Sensitivity of CT scan for diagnosing insulinoma was 33-64%. With the recent advances in technology and knowledge of rapid contrast enhanced CT scan in early phase has increased the sentivity to 80% [1]Most insulinomas are smaller,<1.3 cm (50%) and many of these are non contour forming. therefore CT scan is less effective in diagnosing them than MRI.[2][3]
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Insulinoma-Case courtesy of Dr. Bruno Di Muzio, Radiopaedia.org, rID: 21569
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Insulinoma-Case courtesy of Dr. Mustafa Hammad, Radiopaedia.org, rID: 47669
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Metatstatic Insulinoma-Case courtesy of Dr. Maxime St-Amant, Radiopaedia.org, rID: 19080
- Abdominal Contrast enhanced CT(CECT) scan may be helpful in the diagnosis of insulinoma. Findings on CT scan suggestive of insulinoma include[1]:
- greater degree of enhancement than parenchyma of the rest of pancreas(as its hypervascular)during the vascular phases of the contrast
- atypically can appear hypovascular and hypodense lesions after the administration of contrast, as compared to hyperdense lesions before the administration; cystic masses, and calcified masses(in malignant lesions when they are nodular and discrete)[2][3]
- CT quality have been improved with techology advances with using dual-phase thin-section multdetector CT having senstivity of 94.4% as compared to 57% for dual-phase multidetector without thin sections and 28.6% with sequential CT.[2][4]
References
- ↑ 1.0 1.1 Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y, Kobayashi M, Hanazaki K (2013). "Diagnosis and management of insulinoma". World J. Gastroenterol. 19 (6): 829–37. doi:10.3748/wjg.v19.i6.829. PMC 3574879. PMID 23430217.
- ↑ 2.0 2.1 2.2 McAuley G, Delaney H, Colville J, Lyburn I, Worsley D, Govender P; et al. (2005). "Multimodality preoperative imaging of pancreatic insulinomas". Clin Radiol. 60 (10): 1039–50. doi:10.1016/j.crad.2005.06.005. PMID 16179163.
- ↑ 3.0 3.1 Noone TC, Hosey J, Firat Z, Semelka RC (2005). "Imaging and localization of islet-cell tumours of the pancreas on CT and MRI". Best Pract Res Clin Endocrinol Metab. 19 (2): 195–211. doi:10.1016/j.beem.2004.11.013. PMID 15763695.
- ↑ Tucker ON, Crotty PL, Conlon KC (2006). "The management of insulinoma". Br J Surg. 93 (3): 264–75. doi:10.1002/bjs.5280. PMID 16498592.