Insulinoma MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI | |||
[Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3]. | |||
OR | |||
There are no MRI findings associated with [disease name]. However, a MRI may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3]. | |||
==MRI== | ==MRI== | ||
MRI is superior in detecting insulinoma in that it has greater sensitivity currently ~85%. In a study of 21 insulinomas by Owen et al,the sensitivity was noted to be 94%.(19/21 cases). The 2 cases were of 5 and 7 mm size | MRI is superior in detecting insulinoma in that it has greater sensitivity currently ~85%. In a study of 21 insulinomas by Owen et al,the sensitivity was noted to be 94%.(19/21 cases). The 2 cases were of 5 and 7 mm size<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319 }} </ref><ref name="pmid10671597">{{cite journal| author=Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB| title=Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. | journal=Radiology | year= 2000 | volume= 214 | issue= 2 | pages= 483-90 | pmid=10671597 | doi=10.1148/radiology.214.2.r00fe32483 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10671597 }} </ref> | ||
<gallery widths="250px"> | <gallery widths="250px"> | ||
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*T1 and T2 relaxation times for islet cell tumor like insulinoma has lower protein and proton concentration time | *T1 and T2 relaxation times for islet cell tumor like insulinoma has lower protein and proton concentration time | ||
* | *[Location] MRI may be helpful in the diagnosis of insulinoma. Findings on MRI suggestive of Insulinoma include: | ||
**Low in signal intensity on fat suppressed T1-weighted images | **Low in signal intensity on fat suppressed T1-weighted images | ||
**High on intensity on fat suppressed T2-weighted images independent of lesion size | **High on intensity on fat suppressed T2-weighted images independent of lesion size | ||
**Enhancement patterns are due to hypervascularity | **Enhancement patterns are due to hypervascularity and include: | ||
**same pattern can be seen in metastatic lymph node as of the primary | ***homogenous | ||
***ring | |||
***diffusely heterogenous patterns immediately after administration of contrast | |||
**Low in intensity on T2 weighted images indicate desmoplasia or malignancy | |||
**same pattern can be seen in metastatic lymph node as of the primary. | |||
==References== | ==References== | ||
Revision as of 20:27, 23 August 2017
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Insulinoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Insulinoma MRI On the Web |
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American Roentgen Ray Society Images of Insulinoma MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
[Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
OR
There are no MRI findings associated with [disease name]. However, a MRI may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].
MRI
MRI is superior in detecting insulinoma in that it has greater sensitivity currently ~85%. In a study of 21 insulinomas by Owen et al,the sensitivity was noted to be 94%.(19/21 cases). The 2 cases were of 5 and 7 mm size[1][2]
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Insulinoma T1 fat sat- Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma (Axial T1 C+fat sat)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma (Axial T2 fat sat)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma(T1C+ PV)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma- Case courtesy of Dr J. Ray Ballinger, Radiopaedia.org, rID: 23627 -
Insulinoma-Case courtesy of Dr Alejandro Cruz, Radiopaedia.org, rID: 30096
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- T1 and T2 relaxation times for islet cell tumor like insulinoma has lower protein and proton concentration time
- [Location] MRI may be helpful in the diagnosis of insulinoma. Findings on MRI suggestive of Insulinoma include:
- Low in signal intensity on fat suppressed T1-weighted images
- High on intensity on fat suppressed T2-weighted images independent of lesion size
- Enhancement patterns are due to hypervascularity and include:
- homogenous
- ring
- diffusely heterogenous patterns immediately after administration of contrast
- Low in intensity on T2 weighted images indicate desmoplasia or malignancy
- same pattern can be seen in metastatic lymph node as of the primary.
References
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
- ↑ Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB (2000). "Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity". Radiology. 214 (2): 483–90. doi:10.1148/radiology.214.2.r00fe32483. PMID 10671597.