Insulinoma other imaging findings: Difference between revisions
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==Other Imaging Findings== | ==Other Imaging Findings== | ||
===Positron Emission Tomography== | ===Positron Emission Tomography=== | ||
===Somatostatin receptor scintigraphy=== | ===Somatostatin receptor scintigraphy=== | ||
*Somatostatin receptor scintigraphy(SRS) may be helpful in the diagnosis of pancreatic neuroendocrine tumors including insulinomas. As many insulinomas does not express [[somatostatin]]subtype 2 receptors, it is less sensitive(50-60%).<ref name="pmid8944566">{{cite journal| author=Zimmer T, Stölzel U, Bäder M, Koppenhagen K, Hamm B, Buhr H et al.| title=Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localisation of insulinomas and gastrinomas. | journal=Gut | year= 1996 | volume= 39 | issue= 4 | pages= 562-8 | pmid=8944566 | doi= | pmc=1383270 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8944566 }} </ref><ref name="pmid9854595">{{cite journal| author=Proye C, Malvaux P, Pattou F, Filoche B, Godchaux JM, Maunoury V et al.| title=Noninvasive imaging of insulinomas and gastrinomas with endoscopic ultrasonography and somatostatin receptor scintigraphy. | journal=Surgery | year= 1998 | volume= 124 | issue= 6 | pages= 1134-43; discussion 1143-4 | pmid=9854595 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9854595 }} </ref> <ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref><ref name="pmid7513113">{{cite journal| author=Behr T, Becker W, Koch W, Grebmeier J, Wolf F| title=[Somatostatin receptor scintigraphy in neuroendocrine tumors exemplified by a patient with hepatic metastases of gastrinoma]. | journal=Z Gastroenterol | year= 1994 | volume= 32 | issue= 2 | pages= 100-4 | pmid=7513113 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7513113 }} </ref> | *Somatostatin receptor scintigraphy(SRS) may be helpful in the diagnosis of pancreatic neuroendocrine tumors including insulinomas. As many insulinomas does not express [[somatostatin]]subtype 2 receptors, it is less sensitive(50-60%).<ref name="pmid8944566">{{cite journal| author=Zimmer T, Stölzel U, Bäder M, Koppenhagen K, Hamm B, Buhr H et al.| title=Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localisation of insulinomas and gastrinomas. | journal=Gut | year= 1996 | volume= 39 | issue= 4 | pages= 562-8 | pmid=8944566 | doi= | pmc=1383270 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8944566 }} </ref><ref name="pmid9854595">{{cite journal| author=Proye C, Malvaux P, Pattou F, Filoche B, Godchaux JM, Maunoury V et al.| title=Noninvasive imaging of insulinomas and gastrinomas with endoscopic ultrasonography and somatostatin receptor scintigraphy. | journal=Surgery | year= 1998 | volume= 124 | issue= 6 | pages= 1134-43; discussion 1143-4 | pmid=9854595 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9854595 }} </ref> <ref name="McAuleyDelaney2005">{{cite journal|last1=McAuley|first1=G.|last2=Delaney|first2=H.|last3=Colville|first3=J.|last4=Lyburn|first4=I.|last5=Worsley|first5=D.|last6=Govender|first6=P.|last7=Torreggiani|first7=W.C.|title=Multimodality preoperative imaging of pancreatic insulinomas|journal=Clinical Radiology|volume=60|issue=10|year=2005|pages=1039–1050|issn=00099260|doi=10.1016/j.crad.2005.06.005}}</ref><ref name="pmid7513113">{{cite journal| author=Behr T, Becker W, Koch W, Grebmeier J, Wolf F| title=[Somatostatin receptor scintigraphy in neuroendocrine tumors exemplified by a patient with hepatic metastases of gastrinoma]. | journal=Z Gastroenterol | year= 1994 | volume= 32 | issue= 2 | pages= 100-4 | pmid=7513113 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7513113 }} </ref> | ||
Findings on an SRS suggestive of/diagnostic of insulinoma include: | Findings on an SRS suggestive of/diagnostic of insulinoma include: | ||
**Increased uptake of pentetereotride(synthetic somatostatin analogue) | **Increased uptake of pentetereotride(synthetic somatostatin analogue) | ||
**Increased uptake in sites of metastasis, commonly in hepatic involvement | |||
==References== | ==References== | ||
Revision as of 19:00, 31 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
There are no other imaging findings associated with [disease name].
OR
[Imaging modality] may be helpful in the diagnosis of [disease name]. Findings on an [imaging modality] suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
Other Imaging Findings
Positron Emission Tomography
Somatostatin receptor scintigraphy
- Somatostatin receptor scintigraphy(SRS) may be helpful in the diagnosis of pancreatic neuroendocrine tumors including insulinomas. As many insulinomas does not express somatostatinsubtype 2 receptors, it is less sensitive(50-60%).[1][2] [3][4]
Findings on an SRS suggestive of/diagnostic of insulinoma include:
- Increased uptake of pentetereotride(synthetic somatostatin analogue)
- Increased uptake in sites of metastasis, commonly in hepatic involvement
References
- ↑ Zimmer T, Stölzel U, Bäder M, Koppenhagen K, Hamm B, Buhr H; et al. (1996). "Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localisation of insulinomas and gastrinomas". Gut. 39 (4): 562–8. PMC 1383270. PMID 8944566.
- ↑ Proye C, Malvaux P, Pattou F, Filoche B, Godchaux JM, Maunoury V; et al. (1998). "Noninvasive imaging of insulinomas and gastrinomas with endoscopic ultrasonography and somatostatin receptor scintigraphy". Surgery. 124 (6): 1134–43, discussion 1143-4. PMID 9854595.
- ↑ McAuley, G.; Delaney, H.; Colville, J.; Lyburn, I.; Worsley, D.; Govender, P.; Torreggiani, W.C. (2005). "Multimodality preoperative imaging of pancreatic insulinomas". Clinical Radiology. 60 (10): 1039–1050. doi:10.1016/j.crad.2005.06.005. ISSN 0009-9260.
- ↑ Behr T, Becker W, Koch W, Grebmeier J, Wolf F (1994). "[Somatostatin receptor scintigraphy in neuroendocrine tumors exemplified by a patient with hepatic metastases of gastrinoma]". Z Gastroenterol. 32 (2): 100–4. PMID 7513113.