Hypoaldosteronism classification: Difference between revisions
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==Classification== | ==Classification== | ||
Hypoaldosteronism may be classified depending on the level of [[Plasma renin activity|plasma renin]] and depending on the level of [[aldosterone]] into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance. | Hypoaldosteronism may be classified depending on the level of [[Plasma renin activity|plasma renin]] and depending on the level of [[aldosterone]] into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance.<ref name="BatlleKurtzman1982">{{cite journal|last1=Batlle|first1=Daniel|last2=Kurtzman|first2=Neil A.|title=Distal Renal Tubular Acidosis: Pathogenesis and Classification|journal=American Journal of Kidney Diseases|volume=1|issue=6|year=1982|pages=328–344|issn=02726386|doi=10.1016/S0272-6386(82)80004-8}}</ref> | ||
===Based on the level of plasma renin=== | ===Based on the level of plasma renin=== |
Revision as of 19:53, 31 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
Hypoaldosteronism may be classified into two categories depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance.
Classification
Hypoaldosteronism may be classified depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance.[1]
Based on the level of plasma renin
Hypoaldosteronism can be classified on the basis of plasma renin activity into hyporeninemic or hyperreninemic hypoaldosteronism.
Hypoaldosteronism | |||||||||||||||||||||||||||||||||||||||
Hyporeninemic Hypoaldosteronism | Hyperreninemic Hypoaldosteronism | ||||||||||||||||||||||||||||||||||||||
•Renal insufficiency •Diabetic nephropathy •Sickle cell disease | •Addison's disease • Any severe illness such as malignancy or sepsis | ||||||||||||||||||||||||||||||||||||||
Based on the level of aldosterone
Hypoaldosteronism can also be classified on the basis of level of aldosterone.
Hypoaldosteronism | |||||||||||||||||||||||||||||||||||||||
Aldosterone deficiency | Aldosterone resistance | ||||||||||||||||||||||||||||||||||||||
•Renal insufficiency •Adrenal insufficiency • Diabetic nephropathy •Sickle cell disease •Critical illness •Congenital isolated hypoaldosteronism • Drugs such as ACEi, ARBs and Heparin | • Pseudohypoaldosteronism type 1 • Aldosterone antagonists • Epithelial sodium channel blockers • Calcineurin inhibitors | ||||||||||||||||||||||||||||||||||||||
References
- ↑ Batlle, Daniel; Kurtzman, Neil A. (1982). "Distal Renal Tubular Acidosis: Pathogenesis and Classification". American Journal of Kidney Diseases. 1 (6): 328–344. doi:10.1016/S0272-6386(82)80004-8. ISSN 0272-6386.