Hirsutism natural history, complications and prognosis: Difference between revisions

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Revision as of 14:45, 14 September 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

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Age of onset
- Idiopathic hirsutism and the other less-serious causes of hirsutism usually begin at puberty.
- Hirsutism that occurs in middle-aged or older women may suggest an adrenal or ovarian tumor.
Family history: A patient with a family history of hirsutism is consistent with CAH; however, idiopathic hirsutism and polycystic ovary syndrome (PCOS) can also be familial.
- Hirsutism severity and rate of progression
  - The history of a benign form of hirsutism is usually characterized by pubertal onset with slow progression over many years. This is often true of hirsutism with PCOS.
  - When a history of rapid severe hirsutism or other signs of virilization are obtained, an androgen-secreting tumor is a possibility.
- Adrenarche and puberty
  - Because the development of pubic hair depends on adrenal androgens, early development points toward CAH.
  - In contrast, ovarian hyperandrogenism is associated with normal adrenarche and delayed menarche or irregular menses.

Prognosis depends on the underlynig cause of the hirsutism and whether it is benign or malignant.^[1]

@@ Line 9: / Line 9: @@
 ==Natural History, Complications and Prognosis==
 ===Natural History===
+* Age of onset
+** Idiopathic hirsutism and the other less-serious causes of hirsutism usually begin at puberty.
+** Hirsutism that occurs in middle-aged or older women may suggest an adrenal or ovarian tumor.
+* Family history: A patient with a family history of hirsutism is consistent with CAH; however, idiopathic hirsutism and polycystic ovary syndrome (PCOS) can also be familial.
+** Hirsutism severity and rate of progression
+*** The history of a benign form of hirsutism is usually characterized by pubertal onset with slow progression over many years. This is often true of hirsutism with PCOS.
+*** When a history of rapid severe hirsutism or other signs of virilization are obtained, an androgen-secreting tumor is a possibility.
+** Adrenarche and puberty
+*** Because the development of pubic hair depends on adrenal androgens, early development points toward CAH.
+*** In contrast, ovarian hyperandrogenism is associated with normal adrenarche and delayed menarche or irregular menses.
 ===Complications===