Delayed puberty classification: Difference between revisions
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==Overview== | ==Overview== | ||
Delayed puberty is almost always due to [[physiologic]] exaggerated prolongation of [[puberty]] timing | Delayed puberty is almost always due to [[physiologic]] exaggerated prolongation of [[puberty]] timing, a condition called [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]]. Other forms of delayed puberty include hypergonadotropic [[hypogonadism]], permanent [[hypogonadotropic hypogonadism]], and functional [[hypogonadotropic hypogonadism]]. | ||
==Classification== | ==Classification== | ||
Delayed puberty | * Delayed puberty may be classified according to etiology into 4 subtypes, include [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]], hypergonadotropic [[hypogonadism]], permanent [[hypogonadotropic hypogonadism]], and functional [[hypogonadotropic hypogonadism]]. | ||
* The most common subtype of delayed puberty, [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]], has no pathological etiology and is completely physiologic. | |||
* Other subtypes of delayed puberty are classified upon the serum levels of [[sex hormones]] and also [[gonadotropins]]. | |||
* The complete classification of delayed puberty is as follows:<ref name="PalmertDunkel2012">{{cite journal|last1=Palmert|first1=Mark R.|last2=Dunkel|first2=Leo|title=Delayed Puberty|journal=New England Journal of Medicine|volume=366|issue=5|year=2012|pages=443–453|issn=0028-4793|doi=10.1056/NEJMcp1109290}}</ref> | |||
{{Family tree/start}} | {{Family tree/start}} |
Revision as of 19:53, 14 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Overview
Delayed puberty is almost always due to physiologic exaggerated prolongation of puberty timing, a condition called constitutional delay of growth and puberty (CDGP). Other forms of delayed puberty include hypergonadotropic hypogonadism, permanent hypogonadotropic hypogonadism, and functional hypogonadotropic hypogonadism.
Classification
- Delayed puberty may be classified according to etiology into 4 subtypes, include constitutional delay of growth and puberty (CDGP), hypergonadotropic hypogonadism, permanent hypogonadotropic hypogonadism, and functional hypogonadotropic hypogonadism.
- The most common subtype of delayed puberty, constitutional delay of growth and puberty (CDGP), has no pathological etiology and is completely physiologic.
- Other subtypes of delayed puberty are classified upon the serum levels of sex hormones and also gonadotropins.
- The complete classification of delayed puberty is as follows:[1]
Delayed puberty classification | |||||||||||||||||||||||||||||||||||||||||||||||||
LH, FSH, and GnRH measurement | |||||||||||||||||||||||||||||||||||||||||||||||||
Normal | Abnormal | ||||||||||||||||||||||||||||||||||||||||||||||||
Constitutional delay of growth and puberty (CDGP) | LH and FSH increased GnRH increased | LH and FSH decreased GnRH decreased | LH and FSH decreased GnRH decreased (transient) | ||||||||||||||||||||||||||||||||||||||||||||||
Hypergonadotropic hypogonadism (primary hypogonadism) | Permanent hypogonadotropic hypogonadism (secondary hypogonadism) | Transient hypogonadotropic hypogonadism (functional hypogonadism) | |||||||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Palmert, Mark R.; Dunkel, Leo (2012). "Delayed Puberty". New England Journal of Medicine. 366 (5): 443–453. doi:10.1056/NEJMcp1109290. ISSN 0028-4793.