Insulinoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of insulinoma include gender | Common risk factors in the development of insulinoma include female gender, age:40-60 years, [[Multiple endocrine neoplasia type 1|MEN1]] syndrome, [[Von Hippel-Lindau Disease|von Hippel-Lindau]] disease, and [[Neurofibromatosis type I|Neurofibromatosis 1]]. | ||
==Risk Factors== | ==Risk Factors== | ||
===Common Risk Factors=== | ===Common Risk Factors=== | ||
*Common risk factors in the development of insulinoma include: | *Common [[risk factors]] in the development of insulinoma include: | ||
**Gender: [[Females]] are more at risk of developing insulinoma than [[males]] | **Gender: [[Females]] are more at risk of developing insulinoma than [[males]]. | ||
**[[Age]]: People who are in the age range of 40-60 years | **[[Age]]: People who are in the age range of 40-60 years. | ||
**[[Genetics]]: persons with [[family history]] of [[pancreatic neuroendocrine tumor]]<nowiki/>s are at higher risk of developing insulinomas<ref name="pmid23742779">{{cite journal| author=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G| title=Risk factors for the occurrence of insulinoma: a case-control study. | journal=Hepatobiliary Pancreat Dis Int | year= 2013 | volume= 12 | issue= 3 | pages= 324-8 | pmid=23742779 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23742779 }} </ref> | **[[Genetics]]: persons with [[family history]] of [[pancreatic neuroendocrine tumor]]<nowiki/>s are at higher risk of developing insulinomas. <ref name="pmid23742779">{{cite journal| author=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G| title=Risk factors for the occurrence of insulinoma: a case-control study. | journal=Hepatobiliary Pancreat Dis Int | year= 2013 | volume= 12 | issue= 3 | pages= 324-8 | pmid=23742779 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23742779 }} </ref> | ||
***People with associated [[Multiple endocrine neoplasia type 1]] syndrome ([[Multiple endocrine neoplasia type 1|MEN 1]])<ref name="pmid1677058">{{cite journal| author=Service FJ, McMahon MM, O'Brien PC, Ballard DJ| title=Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study. | journal=Mayo Clin Proc | year= 1991 | volume= 66 | issue= 7 | pages= 711-9 | pmid=1677058 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1677058 }} </ref><ref name="pmid9735690">{{cite journal| author=Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH| title=Insulinoma--experience from 1950 to 1995. | journal=West J Med | year= 1998 | volume= 169 | issue= 2 | pages= 98-104 | pmid=9735690 | doi= | pmc=1305178 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9735690 }} </ref><ref name="pmid23742779">{{cite journal |vauthors=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G |title=Risk factors for the occurrence of insulinoma: a case-control study |journal=HBPD INT |volume=12 |issue=3 |pages=324–8 |year=2013 |pmid=23742779 |doi= |url=}}</ref><ref name="urlInsulinoma - Health Encyclopedia - University of Rochester Medical Center">{{cite web |url=https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=134&contentid=219 |title=Insulinoma - Health Encyclopedia - University of Rochester Medical Center |format= |work= |accessdate=}}</ref> | ***People with associated [[Multiple endocrine neoplasia type 1]] syndrome ([[Multiple endocrine neoplasia type 1|MEN 1]]) <ref name="pmid1677058">{{cite journal| author=Service FJ, McMahon MM, O'Brien PC, Ballard DJ| title=Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study. | journal=Mayo Clin Proc | year= 1991 | volume= 66 | issue= 7 | pages= 711-9 | pmid=1677058 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1677058 }} </ref><ref name="pmid9735690">{{cite journal| author=Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH| title=Insulinoma--experience from 1950 to 1995. | journal=West J Med | year= 1998 | volume= 169 | issue= 2 | pages= 98-104 | pmid=9735690 | doi= | pmc=1305178 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9735690 }} </ref><ref name="pmid23742779">{{cite journal |vauthors=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G |title=Risk factors for the occurrence of insulinoma: a case-control study |journal=HBPD INT |volume=12 |issue=3 |pages=324–8 |year=2013 |pmid=23742779 |doi= |url=}}</ref><ref name="urlInsulinoma - Health Encyclopedia - University of Rochester Medical Center">{{cite web |url=https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=134&contentid=219 |title=Insulinoma - Health Encyclopedia - University of Rochester Medical Center |format= |work= |accessdate=}}</ref> | ||
===Less Common Risk Factors=== | ===Less Common Risk Factors=== | ||
*Less common risk factors in the development of insulinoma include: | *Less common [[risk factors]] in the development of insulinoma include: | ||
**[[Von Hippel-Lindau Disease| | **[[Von Hippel-Lindau Disease|Von Hippel-Lindau]] disease | ||
**[[Neurofibromatosis type I|Neurofibromatosis]] type 1<ref name="pmid23742779">{{cite journal |vauthors=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G |title=Risk factors for the occurrence of insulinoma: a case-control study |journal=HBPD INT |volume=12 |issue=3 |pages=324–8 |year=2013 |pmid=23742779 |doi= |url=}}</ref><ref name="urlInsulinoma - Health Encyclopedia - University of Rochester Medical Center">{{cite web |url=https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=134&contentid=219 |title=Insulinoma - Health Encyclopedia - University of Rochester Medical Center |format= |work= |accessdate=}}</ref> | **[[Neurofibromatosis type I|Neurofibromatosis]] type 1 <ref name="pmid23742779">{{cite journal |vauthors=Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G |title=Risk factors for the occurrence of insulinoma: a case-control study |journal=HBPD INT |volume=12 |issue=3 |pages=324–8 |year=2013 |pmid=23742779 |doi= |url=}}</ref><ref name="urlInsulinoma - Health Encyclopedia - University of Rochester Medical Center">{{cite web |url=https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=134&contentid=219 |title=Insulinoma - Health Encyclopedia - University of Rochester Medical Center |format= |work= |accessdate=}}</ref> | ||
==References== | ==References== | ||
Revision as of 13:53, 22 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
Common risk factors in the development of insulinoma include female gender, age:40-60 years, MEN1 syndrome, von Hippel-Lindau disease, and Neurofibromatosis 1.
Risk Factors
Common Risk Factors
- Common risk factors in the development of insulinoma include:
- Gender: Females are more at risk of developing insulinoma than males.
- Age: People who are in the age range of 40-60 years.
- Genetics: persons with family history of pancreatic neuroendocrine tumors are at higher risk of developing insulinomas. [1]
Less Common Risk Factors
- Less common risk factors in the development of insulinoma include:
- Von Hippel-Lindau disease
- Neurofibromatosis type 1 [1][4]
References
- ↑ 1.0 1.1 1.2 Zhan HX, Cong L, Zhao YP, Zhang TP, Chen G (2013). "Risk factors for the occurrence of insulinoma: a case-control study". Hepatobiliary Pancreat Dis Int. 12 (3): 324–8. PMID 23742779.
- ↑ Service FJ, McMahon MM, O'Brien PC, Ballard DJ (1991). "Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study". Mayo Clin Proc. 66 (7): 711–9. PMID 1677058.
- ↑ Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH (1998). "Insulinoma--experience from 1950 to 1995". West J Med. 169 (2): 98–104. PMC 1305178. PMID 9735690.
- ↑ 4.0 4.1 "Insulinoma - Health Encyclopedia - University of Rochester Medical Center".