Hyperparathyroidism classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.

Classification

Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.

Primary hyperparathyroidism

• Primary hyperparathyroidism is due to over activity of the parathyroid glands themselves. The most important causes of oversecretion of parathyroid hormone include:
• Adenoma
• Hyperplasia
• Carcinoma of the parathyroid glands

Secondary hyperparathyroidism

Secondary hyperparathyroidism is due to increase in secretion of parathyroid hormone from a secondary process.

Tertiary hyperparathyroidism

Tertiary hyperparathyroidism is a state of excessive secretion of parathyroid hormone (PTH) after a long period of secondary hyperparathyroidism and resulting in hypercalcemia.

Hyperparathyroidism

Primary hyperparathyroidism

Secondary hyperparathyroidism

Tertiary hyperparathyroidosm

•Parathyroid adenoma •Parathyroid hyperplasia •Parathyroid carcinoma

•Chronic renal failure •Vitamin D deficiency

•Post-renal transplantation