Primary biliary cirrhosis classification: Difference between revisions
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==Classification== | ==Classification== | ||
There is no established system for the classification of primary biliary cirrhosis. However, it can be classified into four stages according to histological classification of Ludwig. According to Ludwig classification, all four stages may be present on a single liver biopsy.<ref name="pmid19554543">{{cite journal| author=Lindor KD, Gershwin ME, Poupon R, Kaplan M, Bergasa NV, Heathcote EJ et al.| title=Primary biliary cirrhosis. | journal=Hepatology | year= 2009 | volume= 50 | issue= 1 | pages= 291-308 | pmid=19554543 | doi=10.1002/hep.22906 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19554543 }} </ref> | |||
===Stage 1=== | ===Stage 1=== | ||
Stage 1 is characterized by portal inflammation. | *Stage 1 is characterized by portal inflammation. | ||
===Stage 2=== | ===Stage 2=== | ||
Extension of inflammation beyond portal tracts into surrounding parenchyma with or without ductal loss. | *Extension of inflammation beyond portal tracts into surrounding parenchyma with or without ductal loss. | ||
===Stage 3=== | ===Stage 3=== | ||
There is presence of fibrous septa linking adjacent portal tracts. | *There is presence of fibrous septa linking adjacent portal tracts. | ||
===Stage 4=== | ===Stage 4=== | ||
Stage 4 is characterized by cirrhosis. | *Stage 4 is characterized by cirrhosis. | ||
==References== | ==References== | ||
Revision as of 23:10, 22 October 2017
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Primary Biliary Cirrhosis Microchapters |
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Differentiating Primary Biliary Cirrhosis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary biliary cirrhosis classification On the Web |
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American Roentgen Ray Society Images of Primary biliary cirrhosis classification |
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Risk calculators and risk factors for Primary biliary cirrhosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There is no established system for the classification of Primary biliary cirrhosis. However, it can be classified into four stages depending on the histology of the disease.[1]
Classification
There is no established system for the classification of primary biliary cirrhosis. However, it can be classified into four stages according to histological classification of Ludwig. According to Ludwig classification, all four stages may be present on a single liver biopsy.[1]
Stage 1
- Stage 1 is characterized by portal inflammation.
Stage 2
- Extension of inflammation beyond portal tracts into surrounding parenchyma with or without ductal loss.
Stage 3
- There is presence of fibrous septa linking adjacent portal tracts.
Stage 4
- Stage 4 is characterized by cirrhosis.
References
- ↑ 1.0 1.1 Lindor KD, Gershwin ME, Poupon R, Kaplan M, Bergasa NV, Heathcote EJ; et al. (2009). "Primary biliary cirrhosis". Hepatology. 50 (1): 291–308. doi:10.1002/hep.22906. PMID 19554543.