Irritable bowel syndrome causes

Irritable bowel syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Irritable bowel syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Monitoring
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Case Studies
Case #1
Irritable bowel syndrome causes On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Irritable bowel syndrome causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Irritable bowel syndrome causes
CDC on Irritable bowel syndrome causes
Irritable bowel syndrome causes in the news
Blogs on Irritable bowel syndrome causes
Directions to Hospitals Treating Irritable bowel syndrome
Risk calculators and risk factors for Irritable bowel syndrome causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The most common cause of IBS is emotional disturbances, stress, adverse early life events, history of Inflammatory bowel disease, acute gastrointestinal infections. Less common causes of IBS include genetics and hormonal changes.

Causes

Common Causes

IBS may be caused by:

• Emotional disturbance or stress
• Adverse early life events
• Anxiety, depression
• History of acute GI infections e.g. Salmonella infection, Giardiasis
• Antibiotic use causing alteration of gut microflora
• History of gastrointestinal disorders like IBD
• Immune causes: history of IBD, Celiac disease, microscopic colitis

Less Common Causes

Less common causes of disease name include:

• Genetics
• Hormonal changes

Genetic Causes

• IBS is caused by a mutation of type V (alpha subunit) of SCN5A-encoded voltage gated sodium channel gene. Other genes such as tumour necrosis factor alpha (TNFα) and genes coding for superfamily member 15 (TNFSF15) are also involved.
• SNPs (Single Nucleotide Polymorphisms) in genes play an important role in host-microbiota interaction (TLR9, IL-6 and CDH1), immune activation and epithelial barriers.

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

List the causes of the disease in alphabetical order.

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.

3