Toxic megacolon laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings consistent with the diagnosis of toxic megacolon include:<ref name="pmid24163654">{{cite journal |vauthors=Antonopoulos P, Almyroudi M, Kolonia V, Kouris S, Troumpoukis N, Economou N |title=Toxic Megacolon and Acute Ischemia of the Colon due to Sigmoid Stenosis Related to Diverticulitis |journal=Case Rep Gastroenterol |volume=7 |issue=3 |pages=409–13 |year=2013 |pmid=24163654 |pmc=3806696 |doi=10.1159/000355345 | *Laboratory findings consistent with the diagnosis of toxic megacolon include:<ref name="pmid24163654">{{cite journal |vauthors=Antonopoulos P, Almyroudi M, Kolonia V, Kouris S, Troumpoukis N, Economou N |title=Toxic Megacolon and Acute Ischemia of the Colon due to Sigmoid Stenosis Related to Diverticulitis |journal=Case Rep Gastroenterol |volume=7 |issue=3 |pages=409–13 |year=2013 |pmid=24163654 |pmc=3806696 |doi=10.1159/000355345 |url=}}</ref> | ||
**[[Anemia]] | **[[Anemia]] | ||
**[[Leukocytosis]] | **[[Leukocytosis]] | ||
*Some patients with toxic megacolon may have elevated Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) concentration.<ref name="BrownHaboubi2008">{{cite journal|last1=Brown|first1=S. R.|last2=Haboubi|first2=N.|last3=Hampton|first3=J.|last4=George|first4=B.|last5=Travis|first5=S. P. L.|title=The Management of Acute Severe Colitis: ACPGBI Position Statement|journal=Colorectal Disease|volume=10|year=2008|pages=8–29|issn=14628910|doi=10.1111/j.1463-1318.2008.01682.x}}</ref><ref name="pmid22131898">{{cite journal |vauthors=Strong SA |title=Management of acute colitis and toxic megacolon |journal=Clin Colon Rectal Surg |volume=23 |issue=4 |pages=274–84 |year=2010 |pmid=22131898 |pmc=3134807 |doi=10.1055/s-0030-1268254 |url=}}</ref> | *Some patients with toxic megacolon may have elevated Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) concentration.<ref name="BrownHaboubi2008">{{cite journal|last1=Brown|first1=S. R.|last2=Haboubi|first2=N.|last3=Hampton|first3=J.|last4=George|first4=B.|last5=Travis|first5=S. P. L.|title=The Management of Acute Severe Colitis: ACPGBI Position Statement|journal=Colorectal Disease|volume=10|year=2008|pages=8–29|issn=14628910|doi=10.1111/j.1463-1318.2008.01682.x}}</ref><ref name="pmid22131898">{{cite journal |vauthors=Strong SA |title=Management of acute colitis and toxic megacolon |journal=Clin Colon Rectal Surg |volume=23 |issue=4 |pages=274–84 |year=2010 |pmid=22131898 |pmc=3134807 |doi=10.1055/s-0030-1268254 |url=}}</ref> | ||
*Electrolyte disturbances are common secondary to inflammatory diarrhea, steroid use and ongoing gastrointestinal losses. | *Electrolyte disturbances are common secondary to inflammatory diarrhea, steroid use and ongoing gastrointestinal losses.<ref name="pmid8282262">{{cite journal |vauthors=Panos MZ, Wood MJ, Asquith P |title=Toxic megacolon: the knee-elbow position relieves bowel distension |journal=Gut |volume=34 |issue=12 |pages=1726–7 |year=1993 |pmid=8282262 |pmc=1374472 |doi= |url=}}</ref> | ||
==References== | ==References== |
Revision as of 14:39, 31 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal among patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name].
Laboratory Findings
- Laboratory findings consistent with the diagnosis of toxic megacolon include:[1]
- Some patients with toxic megacolon may have elevated Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) concentration.[2][3]
- Electrolyte disturbances are common secondary to inflammatory diarrhea, steroid use and ongoing gastrointestinal losses.[4]
References
- ↑ Antonopoulos P, Almyroudi M, Kolonia V, Kouris S, Troumpoukis N, Economou N (2013). "Toxic Megacolon and Acute Ischemia of the Colon due to Sigmoid Stenosis Related to Diverticulitis". Case Rep Gastroenterol. 7 (3): 409–13. doi:10.1159/000355345. PMC 3806696. PMID 24163654.
- ↑ Brown, S. R.; Haboubi, N.; Hampton, J.; George, B.; Travis, S. P. L. (2008). "The Management of Acute Severe Colitis: ACPGBI Position Statement". Colorectal Disease. 10: 8–29. doi:10.1111/j.1463-1318.2008.01682.x. ISSN 1462-8910.
- ↑ Strong SA (2010). "Management of acute colitis and toxic megacolon". Clin Colon Rectal Surg. 23 (4): 274–84. doi:10.1055/s-0030-1268254. PMC 3134807. PMID 22131898.
- ↑ Panos MZ, Wood MJ, Asquith P (1993). "Toxic megacolon: the knee-elbow position relieves bowel distension". Gut. 34 (12): 1726–7. PMC 1374472. PMID 8282262.