Irritable bowel syndrome other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
75SeHCAT testing may be helpful in the diagnosis of IBS patients with bile acid diarrhea. The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75. Retention of the isotope is measured by gamma-camera scanning performed a week after administration. | ''75SeHCAT'' testing may be helpful in the diagnosis of [[Irritable bowel syndrome|IBS]] patients with [[bile acid]] [[diarrhea]]. The ''75SeHCAT'' test measures the whole-body retention of ''75Se-homocholyltaurine'', a [[bile acid]] radiolabeled with the [[gamma]]-emitting [[isotope]] [[selenium]]-75. Retention of the [[isotope]] is measured by [[Gamma camera|gamma-camera]] scanning performed a week after administration. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
=== 75SeHCAT test === | === 75SeHCAT test === | ||
*IBS patients with diarrhea sometimes have bile acid diarrhea on 23-seleno-25-homotaurocholic acid (75SeHCAT) testing.<ref name="pmid25913530">{{cite journal |vauthors=Slattery SA, Niaz O, Aziz Q, Ford AC, Farmer AD |title=Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea |journal=Aliment. Pharmacol. Ther. |volume=42 |issue=1 |pages=3–11 |year=2015 |pmid=25913530 |doi=10.1111/apt.13227 |url=}}</ref> | *[[Irritable bowel syndrome|IBS]] patients with [[diarrhea]] sometimes have [[bile acid]] diarrhea on ''23-seleno-25-homotaurocholic acid (75SeHCAT)'' testing.<ref name="pmid25913530">{{cite journal |vauthors=Slattery SA, Niaz O, Aziz Q, Ford AC, Farmer AD |title=Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea |journal=Aliment. Pharmacol. Ther. |volume=42 |issue=1 |pages=3–11 |year=2015 |pmid=25913530 |doi=10.1111/apt.13227 |url=}}</ref> | ||
*The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75. | *The ''75SeHCAT'' test measures the whole-body retention of ''75Se-homocholyltaurine'', a [[bile acid]] radiolabeled with the [[gamma]]-emitting [[isotope]] [[selenium]]-75. | ||
*Retention of the isotope is measured by gamma-camera scanning performed a week after administration.<ref name="pmid9044199">{{cite journal |vauthors=Niaz SK, Sandrasegaran K, Renny FH, Jones BJ |title=Postinfective diarrhoea and bile acid malabsorption |journal=J R Coll Physicians Lond |volume=31 |issue=1 |pages=53–6 |year=1997 |pmid=9044199 |doi= |url=}}</ref><ref name="pmid1916479">{{cite journal |vauthors=Williams AJ, Merrick MV, Eastwood MA |title=Idiopathic bile acid malabsorption--a review of clinical presentation, diagnosis, and response to treatment |journal=Gut |volume=32 |issue=9 |pages=1004–6 |year=1991 |pmid=1916479 |pmc=1379038 |doi= |url=}}</ref> | *Retention of the [[isotope]] is measured by [[gamma]]-camera scanning performed a week after administration.<ref name="pmid9044199">{{cite journal |vauthors=Niaz SK, Sandrasegaran K, Renny FH, Jones BJ |title=Postinfective diarrhoea and bile acid malabsorption |journal=J R Coll Physicians Lond |volume=31 |issue=1 |pages=53–6 |year=1997 |pmid=9044199 |doi= |url=}}</ref><ref name="pmid1916479">{{cite journal |vauthors=Williams AJ, Merrick MV, Eastwood MA |title=Idiopathic bile acid malabsorption--a review of clinical presentation, diagnosis, and response to treatment |journal=Gut |volume=32 |issue=9 |pages=1004–6 |year=1991 |pmid=1916479 |pmc=1379038 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
75SeHCAT testing may be helpful in the diagnosis of IBS patients with bile acid diarrhea. The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75. Retention of the isotope is measured by gamma-camera scanning performed a week after administration.
Other Imaging Findings
75SeHCAT test
- IBS patients with diarrhea sometimes have bile acid diarrhea on 23-seleno-25-homotaurocholic acid (75SeHCAT) testing.[1]
- The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75.
- Retention of the isotope is measured by gamma-camera scanning performed a week after administration.[2][3]
References
- ↑ Slattery SA, Niaz O, Aziz Q, Ford AC, Farmer AD (2015). "Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea". Aliment. Pharmacol. Ther. 42 (1): 3–11. doi:10.1111/apt.13227. PMID 25913530.
- ↑ Niaz SK, Sandrasegaran K, Renny FH, Jones BJ (1997). "Postinfective diarrhoea and bile acid malabsorption". J R Coll Physicians Lond. 31 (1): 53–6. PMID 9044199.
- ↑ Williams AJ, Merrick MV, Eastwood MA (1991). "Idiopathic bile acid malabsorption--a review of clinical presentation, diagnosis, and response to treatment". Gut. 32 (9): 1004–6. PMC 1379038. PMID 1916479.