Toxic megacolon classification: Difference between revisions
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==Classification== | ==Classification== | ||
*There is no established system for the classification of toxic megacolon but it may be classified according to etiology into 2 groups:<ref name="pmid1344622">{{cite journal |vauthors=Morón C |title=[The street sales of food and the cholera epidemic in Latin America] |language=Spanish; Castilian |journal=Arch Latinoam Nutr |volume=42 |issue=3 Suppl |pages=36S–40S |year=1992 |pmid=1344622 |doi= |url=}}</ref><ref name="pmid9482465">{{cite journal |vauthors=Sheth SG, LaMont JT |title=Toxic megacolon |journal=Lancet |volume=351 |issue=9101 |pages=509–13 |year=1998 |pmid=9482465 |doi=10.1016/S0140-6736(97)10475-5 |url=}}</ref><ref name="urlToxic Megacolon Complicating a First Course of Crohn’s Disease: About Two Cases (PDF Download Available)">{{cite web |url=https://www.researchgate.net/publication/261883894_Toxic_Megacolon_Complicating_a_First_Course_of_Crohn%27s_Disease_About_Two_Cases |title=Toxic Megacolon Complicating a First Course of Crohn’s Disease: About Two Cases (PDF Download Available) |format= |work= |accessdate=}}</ref><ref name="pmid9482465">{{cite journal |vauthors=Sheth SG, LaMont JT |title=Toxic megacolon |journal=Lancet |volume=351 |issue=9101 |pages=509–13 |year=1998 |pmid=9482465 |doi=10.1016/S0140-6736(97)10475-5 |url=}}</ref><ref name="pmid3981266">{{cite journal |vauthors=Croswell SC, Lei KY |title=Effect of copper deficiency on the apolipoprotein E-rich high density lipoproteins in rats |journal=J. Nutr. |volume=115 |issue=4 |pages=473–82 |year=1985 |pmid=3981266 |doi= |url=}}</ref> | *There is no established system for the classification of toxic megacolon but it may be classified according to etiology into 2 groups:<ref name="pmid1344622">{{cite journal |vauthors=Morón C |title=[The street sales of food and the cholera epidemic in Latin America] |language=Spanish; Castilian |journal=Arch Latinoam Nutr |volume=42 |issue=3 Suppl |pages=36S–40S |year=1992 |pmid=1344622 |doi= |url=}}</ref><ref name="pmid9482465">{{cite journal |vauthors=Sheth SG, LaMont JT |title=Toxic megacolon |journal=Lancet |volume=351 |issue=9101 |pages=509–13 |year=1998 |pmid=9482465 |doi=10.1016/S0140-6736(97)10475-5 |url=}}</ref><ref name="urlToxic Megacolon Complicating a First Course of Crohn’s Disease: About Two Cases (PDF Download Available)">{{cite web |url=https://www.researchgate.net/publication/261883894_Toxic_Megacolon_Complicating_a_First_Course_of_Crohn%27s_Disease_About_Two_Cases |title=Toxic Megacolon Complicating a First Course of Crohn’s Disease: About Two Cases (PDF Download Available) |format= |work= |accessdate=}}</ref><ref name="pmid9482465">{{cite journal |vauthors=Sheth SG, LaMont JT |title=Toxic megacolon |journal=Lancet |volume=351 |issue=9101 |pages=509–13 |year=1998 |pmid=9482465 |doi=10.1016/S0140-6736(97)10475-5 |url=}}</ref><ref name="pmid3981266">{{cite journal |vauthors=Croswell SC, Lei KY |title=Effect of copper deficiency on the apolipoprotein E-rich high density lipoproteins in rats |journal=J. Nutr. |volume=115 |issue=4 |pages=473–82 |year=1985 |pmid=3981266 |doi= |url=}}</ref><ref name="pmid18953191">{{cite journal |vauthors=Earhart MM |title=The identification and treatment of toxic megacolon secondary to pseudomembranous colitis |journal=Dimens Crit Care Nurs |volume=27 |issue=6 |pages=249–54 |year=2008 |pmid=18953191 |doi=10.1097/01.DCC.0000338869.70035.2b |url=}}</ref> | ||
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!Etiology of toxic megacolon | !Etiology of toxic megacolon | ||
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|Toxic megacolon associated with Clostridium difficile pseudomembranous colitis | |Toxic megacolon associated with Clostridium difficile pseudomembranous colitis | ||
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* 0.3-4 percent of cases of pseudomembranous colitis may develop toxic megacolon | |||
* Toxic megacolon is thought to develop secondary to inflammatory changes that penetrate into the muscularis propria leading to neural injury, altered colonic motility and colonic dilation | |||
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Revision as of 16:16, 15 November 2017
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Toxic Megacolon Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Toxic megacolon classification On the Web |
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American Roentgen Ray Society Images of Toxic megacolon classification |
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Risk calculators and risk factors for Toxic megacolon classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Toxic megacolon may be classified according to etiology into two groups including toxic megacolon associated with inflammatory bowel disease and toxic megacolon associated with Clostridium difficile pseudomembranous colitis.
Classification
- There is no established system for the classification of toxic megacolon but it may be classified according to etiology into 2 groups:[1][2][3][2][4][5]
| Etiology of toxic megacolon | Pathological evolution | CT scan findings | MRI findings |
|---|---|---|---|
| Toxic megacolon associated with ulcerative colitis |
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| Toxic megacolon associated with Crohn's disease |
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| Toxic megacolon associated with Clostridium difficile pseudomembranous colitis |
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| Toxic megacolon associated with ischemic colitis |
- 1. Toxic megacolon associated with inflammatory bowel disease
- 1.1.
- 1.2.
- 2.
- 1. Toxic megacolon associated with inflammatory bowel disease
References
- ↑ Morón C (1992). "[The street sales of food and the cholera epidemic in Latin America]". Arch Latinoam Nutr (in Spanish; Castilian). 42 (3 Suppl): 36S–40S. PMID 1344622.
- ↑ 2.0 2.1 Sheth SG, LaMont JT (1998). "Toxic megacolon". Lancet. 351 (9101): 509–13. doi:10.1016/S0140-6736(97)10475-5. PMID 9482465.
- ↑ "Toxic Megacolon Complicating a First Course of Crohn's Disease: About Two Cases (PDF Download Available)".
- ↑ Croswell SC, Lei KY (1985). "Effect of copper deficiency on the apolipoprotein E-rich high density lipoproteins in rats". J. Nutr. 115 (4): 473–82. PMID 3981266.
- ↑ Earhart MM (2008). "The identification and treatment of toxic megacolon secondary to pseudomembranous colitis". Dimens Crit Care Nurs. 27 (6): 249–54. doi:10.1097/01.DCC.0000338869.70035.2b. PMID 18953191.