Esophageal stricture: Difference between revisions

Jump to navigation Jump to search
Mahda (talk | contribs)
No edit summary
Mahda (talk | contribs)
No edit summary
Line 15: Line 15:
'''For patient information, click [[Esophageal stricture (patient information)|here]]'''
'''For patient information, click [[Esophageal stricture (patient information)|here]]'''


{{CMG}}; {{AE}}{{MA}} [mailto:malihash@bidmc.harvard.edu]   
{{CMG}}; {{AE}}{{MA}} [mailto:malihash@bidmc.harvard.edu] [mailto:malihash@bidmc.harvard.edu]   


==[[Esophageal stricture overview|Overview]]==
==[[Esophageal stricture overview|Overview]]==


==[[Esophageal stricture historical perspective|Historical Perspective]]==
==[[Esophageal stricture historical perspective|Historical Perspective]]==
First intervention for esophaegal stricture was done in the 17 century by whalebone. The first bougienage was performed in 1801. In 1868, esophagoscope was developed for the first time. In 1877, first surgical [[resection]] for esophaegal [[carcinoma]] was performed by Vincenz Czerny. First stent was introduced in 1990.


==[[Esophageal stricture classification|Classification]]==
==[[Esophageal stricture classification|Classification]]==
There is no established system for the classification of [[esophageal]] [[stricture]], but it may be classified into [[benign]] and [[malignant]] according to causes.


==[[Esophageal stricture pathophysiology|Pathophysiology]]==
==[[Esophageal stricture pathophysiology|Pathophysiology]]==
It is thought that [[esophageal]] [[stricture]] is the result of lower pressure of [[esophageal sphincter]] in [[gastroesophageal reflux disease]], esophageal motor disorder, [[inflammation]] and [[fibrosis]] in [[neoplasia]]. The most characteristic finding in [[gross pathology]] is thickening of the lower [[esophageal]] wall in [[gastroesophageal reflux disease]], pale [[mucosa]] in [[lymphocytic]] [[esophagitis]] and [[hemorrhagic]] [[congestion]] in [[caustic]] ingestion.
[[Microscopic]] [[histopathological]] characteristic findings of [[esophageal]] [[stricture]] is inntraepithelial [[lymphocytes]] and [[basal cell]] [[hyperplasia]] in [[gastroesophageal reflux disease]], [[Infiltration (medical)|infiltration]] T [[lymphocytes]] in [[squamous]] [[mucosa]] in [[lymphocytic]] [[esophagitis]] and [[eosinophilic]] [[necrosis]] in [[caustic]] ingestion


==[[Esophageal stricture causes|Causes]]==
==[[Esophageal stricture causes|Causes]]==
Common causes of [[esophageal]] [[stricture]] include [[gastroesophageal reflux disease]] and [[caustic]] ingestions.


==[[Esophageal stricture differential diagnosis|Differentiating Esophageal stricture from other Disorders]]==
==[[Esophageal stricture differential diagnosis|Differentiating Esophageal stricture from other Disorders]]==
Esophageal stricture must be differentiated from plummer-vinson syndrome, [[achalasia]] , [[diffuse esophageal spasm]], [[systemic sclerosis]], [[zenker's diverticulum]], [[Esophageal cancer|esophageal carcinoma]], [[stroke]], motor disorders, [[GERD]][[Esophageal web|, esophageal web]].


==[[Esophageal stricture epidemiology and demographics|Epidemiology and Demographics]]==
==[[Esophageal stricture epidemiology and demographics|Epidemiology and Demographics]]==
Most of [[esophageal]] [[strictures]] are related to [[gastroesophageal reflux disease]]. Overall incidence of [[esophageal stricture]] is approximately 11 per 100,000 individuals and the [[prevalence]] of [[esophageal]][[stricture]] is approximately 70-120 per 100,000 individuals in united states. The [[incidence]] of [[esophageal]] [[stricture]] increases with age. There is no racial predilection to [[esophageal]] [[stricture]]. The risk of [[esophageal]] [[stricture]] is higher in men under 60 yr but there is similar [[incidence]] in men and women after age 60.


==[[Esophageal stricture risk factors|Risk Factors]]==
==[[Esophageal stricture risk factors|Risk Factors]]==
The most potent [[risk factor]] in the development of [[esophageal]] [[stricture]] is frequent [[acid reflux]]. Other [[risk factor]]<nowiki/>s include [[Hiatus hernia|hiatal hernia]], [[obesity]], [[smoking]], [[esophageal dysmotility]], increased [[gastric]] acidity, and heavy [[alcohol]] use.
 


==[[Esophageal stricture natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==
==[[Esophageal stricture natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==
If left untreated, patients with [[esophageal]] [[stricture]] may progress to develop [[pulmonary aspiration]], [[weight loss]], and [[dehydration]]. Common [[complication]]<nowiki/>s of [[esophageal]] [[stricture]] include [[perforation]], [[bleeding]], [[pneumonia]], [[bacteremia]]. [[Prognosis]] is generally good but recurrence of symptoms after [[dilation]] are prevalent and usually recurrent [[dilation]] is necessary.
 


==Diagnosis==
==Diagnosis==

Revision as of 15:30, 22 November 2017

Esophageal stricture
Endoscopic image of a benign peptic stricture
ICD-9 530.3
DiseasesDB 31502
MedlinePlus 000207

Esophageal stricture Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Esophageal stricture from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Procedure
Surgical Management

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Esophageal stricture On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Esophageal stricture

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Esophageal stricture

CDC on Esophageal stricture

Esophageal stricture in the news

Blogs on Esophageal stricture

Directions to Hospitals Treating Esophageal stricture

Risk calculators and risk factors for Esophageal stricture

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2] [3] [4]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Esophageal stricture from other Disorders

Epidemiology and Demographics

Risk Factors

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Rays | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgical | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters


Template:WikiDoc Sources