Large cell carcinoma of the lung causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Causes of large cell carcinoma of the lung, are those of non-small cell lung cancers. Common causes include precursor lesions, such as metaplasia or dysplasia induced by smoking, asbestos exposure, ionizing radiation, atmospheric pollution, and chronic interstitial pneumonitis. Less common causes of large cell carcinoma of the lung include chromium and nickel exposure, vinyl chloride exposure, and inorganic arsenic exposure.

Common Causes

• Common causes of large cell carcinoma of the lung include precursor lesions, such as metaplasia or dysplasia.
• Precursor lesions of large cell carcinoma of the lung, include:

• Smoking (active/passive)
• Asbestos exposure
• Chronic interstitial pneumonitis
• Ionizing radiation
• Atmospheric pollution

Less Common Causes

• Less common causes of large cell carcinoma of the lung, include:

• Inorganic arsenic exposure
• Chromium, nickel exposure
• Vinyl chloride exposure
• Radon exposure
• Halogen ether exposure

References

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