Esophageal cancer natural history, complications and prognosis: Difference between revisions
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==Natural history== | ==Natural history== | ||
==Complications== | ==Complications== | ||
Complications can occur as a product of esophageal cancer or because of radiotherapeutic treatment. | |||
===Complications due to esophageal cancer=== | |||
*Anemia | |||
*Weight loss | |||
*Dysphagia | |||
*Cachexia | |||
*Aspiration pneumonia | |||
*Metastases | |||
===Complications of radiotherapy=== | |||
*Tracheoesophageal fistula | |||
*Postradiotherapy esophageal strictures, may lead to recurrent dysphagia.<ref name="pmid2452006">{{cite journal |vauthors=O'Rourke IC, Tiver K, Bull C, Gebski V, Langlands AO |title=Swallowing performance after radiation therapy for carcinoma of the esophagus |journal=Cancer |volume=61 |issue=10 |pages=2022–6 |year=1988 |pmid=2452006 |doi= |url=}}</ref> | |||
==Prognosis== | ==Prognosis== | ||
===5-Year Survival=== | ===5-Year Survival=== | ||
Revision as of 16:28, 11 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: mHadeel Maksoud M.D.[2]
Overview
Esophageal cancer is associated with a 5 year survival rate of 20%.
Natural history
Complications
Complications can occur as a product of esophageal cancer or because of radiotherapeutic treatment.
Complications due to esophageal cancer
- Anemia
- Weight loss
- Dysphagia
- Cachexia
- Aspiration pneumonia
- Metastases
Complications of radiotherapy
- Tracheoesophageal fistula
- Postradiotherapy esophageal strictures, may lead to recurrent dysphagia.[1]
Prognosis
5-Year Survival
- Between 2004 and 2010, the 5-year relative survival of patients with esophageal cancer was 20 %.[2]
- When stratified by age, the 5-year relative survival of patients with esophageal cancer was 19.8 % and 15.5 % for patients <65 and ≥ 65 years of age respectively.[2]
- The survival of patients with esophageal cancer varies with the stage of the disease.
- Shown below is a table depicting the 5-year relative survival by the stage of esophageal cancer:[2]
| Stage | 5-year relative survival (%), (2004-2010) |
| All stages | 17.5% |
| Localized | 39.6% |
| Regional | 21.1% |
| Distant | 3.8% |
| Unstaged | 11.5% |
Shown below is an image depicting the 5-year conditional relative survival (probability of surviving in the next 5-years) between 1998 and 2010 of esophageal cancer by stage at diagnosis according to SEER. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[2]
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References
- ↑ O'Rourke IC, Tiver K, Bull C, Gebski V, Langlands AO (1988). "Swallowing performance after radiation therapy for carcinoma of the esophagus". Cancer. 61 (10): 2022–6. PMID 2452006.
- ↑ 2.0 2.1 2.2 2.3 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.