Gastric dumping syndrome future or investigational therapies: Difference between revisions
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== Overview == | == Overview == | ||
For investigational therapies of dumping | For investigational therapies of [[Gastric dumping syndrome|dumping syndrome]] include continuous enteral feeding, [[:Category:Drugs|drugs]], electrical pacing of the [[stomach]] and surgical re-intervention may be considered.__NOTOC__ | ||
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{{Gastric dumping syndrome}} | {{Gastric dumping syndrome}} | ||
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==== '''Procedures''' ==== | ==== '''Procedures''' ==== | ||
* Continuous enteral feeding.<ref name="pmid19724252">{{cite journal |vauthors=Tack J, Arts J, Caenepeel P, De Wulf D, Bisschops R |title=Pathophysiology, diagnosis and management of postoperative dumping syndrome |journal=Nat Rev Gastroenterol Hepatol |volume=6 |issue=10 |pages=583–90 |year=2009 |pmid=19724252 |doi=10.1038/nrgastro.2009.148 |url=}}</ref> | * Continuous enteral feeding.<ref name="pmid19724252">{{cite journal |vauthors=Tack J, Arts J, Caenepeel P, De Wulf D, Bisschops R |title=Pathophysiology, diagnosis and management of postoperative dumping syndrome |journal=Nat Rev Gastroenterol Hepatol |volume=6 |issue=10 |pages=583–90 |year=2009 |pmid=19724252 |doi=10.1038/nrgastro.2009.148 |url=}}</ref> | ||
* Electrical stimulation of the small intestine to achieve gastrointestinal pacing in dumping syndrome.<ref name="pmid16836954">{{cite journal |vauthors=Zhang J, Chen JD |title=Pacing the gut in motility disorders |journal=Curr Treat Options Gastroenterol |volume=9 |issue=4 |pages=351–60 |year=2006 |pmid=16836954 |doi= |url=}}</ref> | * Electrical stimulation of the [[small intestine]] to achieve [[Gastrointestinal tract|gastrointestinal]] pacing in [[Gastric dumping syndrome|dumping syndrome]].<ref name="pmid16836954">{{cite journal |vauthors=Zhang J, Chen JD |title=Pacing the gut in motility disorders |journal=Curr Treat Options Gastroenterol |volume=9 |issue=4 |pages=351–60 |year=2006 |pmid=16836954 |doi= |url=}}</ref> | ||
* In dogs prepared with truncal vagotomy, distal gastrectomy, and Roux-en-Y reconstruction, retrograde electrical pacing of the Roux-en-Y reconstruction significantly delayed gastric emptying and absorption of a glucose meal and decreased postcibal hemoconcentration. | * In dogs prepared with truncal [[vagotomy]], distal [[gastrectomy]], and [[Roux-en-Y]] reconstruction, retrograde electrical pacing of the [[Roux-en-Y]] reconstruction significantly delayed [[Stomach|gastric]] emptying and [[absorption]] of a [[glucose]] meal and decreased postcibal [[hemoconcentration]]. | ||
'''Drugs''' | '''Drugs''' | ||
Verapamil may be considered.<ref name="pmid1415124">{{cite journal |vauthors=Chandos B |title=Dumping syndrome and the regulation of peptide YY with verapamil |journal=Am. J. Gastroenterol. |volume=87 |issue=10 |pages=1530–1 |year=1992 |pmid=1415124 |doi= |url=}}</ref> | [[Verapamil]] may be considered.<ref name="pmid1415124">{{cite journal |vauthors=Chandos B |title=Dumping syndrome and the regulation of peptide YY with verapamil |journal=Am. J. Gastroenterol. |volume=87 |issue=10 |pages=1530–1 |year=1992 |pmid=1415124 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 06:27, 13 December 2017
Overview
For investigational therapies of dumping syndrome include continuous enteral feeding, drugs, electrical pacing of the stomach and surgical re-intervention may be considered.
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Future or Investigational Therapies
Procedures
- Continuous enteral feeding.[1]
- Electrical stimulation of the small intestine to achieve gastrointestinal pacing in dumping syndrome.[2]
- In dogs prepared with truncal vagotomy, distal gastrectomy, and Roux-en-Y reconstruction, retrograde electrical pacing of the Roux-en-Y reconstruction significantly delayed gastric emptying and absorption of a glucose meal and decreased postcibal hemoconcentration.
Drugs
Verapamil may be considered.[3]
References
- ↑ Tack J, Arts J, Caenepeel P, De Wulf D, Bisschops R (2009). "Pathophysiology, diagnosis and management of postoperative dumping syndrome". Nat Rev Gastroenterol Hepatol. 6 (10): 583–90. doi:10.1038/nrgastro.2009.148. PMID 19724252.
- ↑ Zhang J, Chen JD (2006). "Pacing the gut in motility disorders". Curr Treat Options Gastroenterol. 9 (4): 351–60. PMID 16836954.
- ↑ Chandos B (1992). "Dumping syndrome and the regulation of peptide YY with verapamil". Am. J. Gastroenterol. 87 (10): 1530–1. PMID 1415124.