PRPF19: Difference between revisions
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{{ | '''Pre-mRNA-processing factor 19''' is a [[protein]] that in humans is encoded by the ''PRPF19'' [[gene]].<ref name="pmid12960389">{{cite journal | author = Mahajan KN, Mitchell BS | title = Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase | journal = Proc Natl Acad Sci U S A | volume = 100 | issue = 19 | pages = 10746–51 |date=September 2003 | pmid = 12960389 | pmc = 196874 | doi = 10.1073/pnas.1631060100 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27339| accessdate = }}</ref> | ||
}} | |||
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| summary_text = In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM]<ref name="entrez" | | summary_text = In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM]<ref name="entrez" /> | ||
}} | }} | ||
==Interactions== | |||
PRPF19 has been shown to [[Protein-protein interaction|interact]] with [[CDC5L]].<ref name=pmid11101529>{{cite journal |last=Ajuh |first=P |authorlink= |author2=Kuster B |author3=Panov K |author4=Zomerdijk J C |author5=Mann M |author6=Lamond A I |date=December 2000 |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry |journal=EMBO J. |volume=19 |issue=23 |pages=6569–81 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 11101529 |doi = 10.1093/emboj/19.23.6569 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=305846 }}</ref> | |||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
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*{{cite journal | *{{cite journal |vauthors=Gerner C, Holzmann K, Meissner M, etal |title=Reassembling proteins and chaperones in human nuclear matrix protein fractions. |journal=J. Cell. Biochem. |volume=74 |issue= 2 |pages= 145–51 |year= 1999 |pmid= 10404385 |doi=10.1002/(SICI)1097-4644(19990801)74:2<145::AID-JCB1>3.0.CO;2-# }} | ||
*{{cite journal | *{{cite journal |vauthors=Gotzmann J, Gerner C, Meissner M, etal |title=hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions. |journal=Exp. Cell Res. |volume=261 |issue= 1 |pages= 166–79 |year= 2000 |pmid= 11082287 |doi= 10.1006/excr.2000.5025 }} | ||
*{{cite journal | *{{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 }} | ||
*{{cite journal | *{{cite journal |vauthors=Jurica MS, Licklider LJ, Gygi SR, etal |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=10.1017/S1355838202021088 | pmc=1370266 }} | ||
*{{cite journal | *{{cite journal |vauthors=Scherl A, Couté Y, Déon C, etal |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617 }} | ||
*{{cite journal | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }} | ||
*{{cite journal | *{{cite journal |vauthors=Makarova OV, Makarov EM, Urlaub H, etal |title=A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. |journal=EMBO J. |volume=23 |issue= 12 |pages= 2381–91 |year= 2004 |pmid= 15175653 |doi= 10.1038/sj.emboj.7600241 | pmc=423283 }} | ||
*{{cite journal | *{{cite journal |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }} | ||
*{{cite journal | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | ||
*{{cite journal | *{{cite journal |vauthors=Andersen JS, Lam YW, Leung AK, etal |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }} | ||
*{{cite journal | *{{cite journal |vauthors=Löscher M, Fortschegger K, Ritter G, etal |title=Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome. |journal=Biochem. J. |volume=388 |issue= Pt 2 |pages= 593–603 |year= 2005 |pmid= 15660529 |doi= 10.1042/BJ20041517 | pmc=1138967 }} | ||
*{{cite journal | *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }} | ||
*{{cite journal | *{{cite journal |vauthors=Zhang N, Kaur R, Lu X, etal |title=The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. |journal=J. Biol. Chem. |volume=280 |issue= 49 |pages= 40559–67 |year= 2006 |pmid= 16223718 |doi= 10.1074/jbc.M508453200 }} | ||
*{{cite journal | *{{cite journal |vauthors=Grillari J, Ajuh P, Stadler G, etal |title=SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. |journal=Nucleic Acids Res. |volume=33 |issue= 21 |pages= 6868–83 |year= 2005 |pmid= 16332694 |doi= 10.1093/nar/gki986 | pmc=1310963 }} | ||
*{{cite journal | *{{cite journal |vauthors=Voglauer R, Chang MW, Dampier B, etal |title=SNEV overexpression extends the life span of human endothelial cells. |journal=Exp. Cell Res. |volume=312 |issue= 6 |pages= 746–59 |year= 2006 |pmid= 16388800 |doi= 10.1016/j.yexcr.2005.11.025 }} | ||
*{{cite journal | author= | *{{cite journal | author=Lu X, Legerski RJ |title=The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage. |journal=Biochem. Biophys. Res. Commun. |volume=354 |issue= 4 |pages= 968–74 |year= 2007 |pmid= 17276391 |doi= 10.1016/j.bbrc.2007.01.097 | pmc=1810354 }} | ||
*{{cite journal | *{{cite journal |vauthors=Fortschegger K, Wagner B, Voglauer R, etal |title=Early embryonic lethality of mice lacking the essential protein SNEV. |journal=Mol. Cell. Biol. |volume=27 |issue= 8 |pages= 3123–30 |year= 2007 |pmid= 17283042 |doi= 10.1128/MCB.01188-06 | pmc=1899945 }} | ||
*{{cite journal | *{{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
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{{Post transcriptional modification}} | |||
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Revision as of 18:44, 7 September 2017
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| External IDs | GeneCards: [1] | ||||||
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| Species | Human | Mouse | |||||
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| Location (UCSC) | n/a | n/a | |||||
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Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene.[1][2]
In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM][2]
Interactions
PRPF19 has been shown to interact with CDC5L.[3]
References
- ↑ Mahajan KN, Mitchell BS (September 2003). "Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase". Proc Natl Acad Sci U S A. 100 (19): 10746–51. doi:10.1073/pnas.1631060100. PMC 196874. PMID 12960389.
- ↑ 2.0 2.1 "Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)".
- ↑ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. ENGLAND. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.
Further reading
- Gerner C, Holzmann K, Meissner M, et al. (1999). "Reassembling proteins and chaperones in human nuclear matrix protein fractions". J. Cell. Biochem. 74 (2): 145–51. doi:10.1002/(SICI)1097-4644(19990801)74:2<145::AID-JCB1>3.0.CO;2-#. PMID 10404385.
- Gotzmann J, Gerner C, Meissner M, et al. (2000). "hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions". Exp. Cell Res. 261 (1): 166–79. doi:10.1006/excr.2000.5025. PMID 11082287.
- Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
- Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
- Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Makarova OV, Makarov EM, Urlaub H, et al. (2004). "A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing". EMBO J. 23 (12): 2381–91. doi:10.1038/sj.emboj.7600241. PMC 423283. PMID 15175653.
- Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
- Löscher M, Fortschegger K, Ritter G, et al. (2005). "Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome". Biochem. J. 388 (Pt 2): 593–603. doi:10.1042/BJ20041517. PMC 1138967. PMID 15660529.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Zhang N, Kaur R, Lu X, et al. (2006). "The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links". J. Biol. Chem. 280 (49): 40559–67. doi:10.1074/jbc.M508453200. PMID 16223718.
- Grillari J, Ajuh P, Stadler G, et al. (2005). "SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly". Nucleic Acids Res. 33 (21): 6868–83. doi:10.1093/nar/gki986. PMC 1310963. PMID 16332694.
- Voglauer R, Chang MW, Dampier B, et al. (2006). "SNEV overexpression extends the life span of human endothelial cells". Exp. Cell Res. 312 (6): 746–59. doi:10.1016/j.yexcr.2005.11.025. PMID 16388800.
- Lu X, Legerski RJ (2007). "The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage". Biochem. Biophys. Res. Commun. 354 (4): 968–74. doi:10.1016/j.bbrc.2007.01.097. PMC 1810354. PMID 17276391.
- Fortschegger K, Wagner B, Voglauer R, et al. (2007). "Early embryonic lethality of mice lacking the essential protein SNEV". Mol. Cell. Biol. 27 (8): 3123–30. doi:10.1128/MCB.01188-06. PMC 1899945. PMID 17283042.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
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