OR2AG1: Difference between revisions

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{{Infobox_gene}}
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'''Olfactory receptor 2AG1''' is a [[protein]] that in humans is encoded by the ''OR2AG1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2AG1 olfactory receptor, family 2, subfamily AG, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144125| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 2, subfamily AG, member 1
| HGNCid = 15142
| Symbol = OR2AG1
| AltSymbols =; OR11-79; OR2AG3
| OMIM = 
| ECnumber = 
| Homologene = 12558
| MGIid = 3030539
| GeneAtlas_image1 = PBB_GE_OR2AG1_gnf1h10947_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 144125
    | Hs_Ensembl = ENSG00000170803
    | Hs_RefseqProtein = NP_001004489
    | Hs_RefseqmRNA = NM_001004489
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 6762845
    | Hs_GenLoc_end = 6763795
    | Hs_Uniprot = Q9H205
    | Mm_EntrezGene = 259034
    | Mm_Ensembl = ENSMUSG00000047120
    | Mm_RefseqmRNA = NM_147032
    | Mm_RefseqProtein = NP_667243
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 106666942
    | Mm_GenLoc_end = 106667892
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 2, subfamily AG, member 1''', also known as '''OR2AG1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2AG1 olfactory receptor, family 2, subfamily AG, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144125| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2AG1 olfactory receptor, family 2, subfamily AG, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144125| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2AG1 olfactory receptor, family 2, subfamily AG, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144125| accessdate = }}</ref>
}}
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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Lane RP, Cutforth T, Young J, ''et al.'' |title=Genomic analysis of orthologous mouse and human olfactory receptor loci. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7390-5 |year= 2001 |pmid= 11416212 |doi= 10.1073/pnas.131215398 }}
*{{cite journal   |vauthors=Lane RP, Cutforth T, Young J, etal |title=Genomic analysis of orthologous mouse and human olfactory receptor loci. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7390–5 |year= 2001 |pmid= 11416212 |doi= 10.1073/pnas.131215398 | pmc=34679 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal   |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
*{{cite journal | author=Neuhaus EM, Mashukova A, Zhang W, ''et al.'' |title=A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins. |journal=Chem. Senses |volume=31 |issue= 5 |pages= 445-52 |year= 2006 |pmid= 16565291 |doi= 10.1093/chemse/bjj049 }}
*{{cite journal   |vauthors=Neuhaus EM, Mashukova A, Zhang W, etal |title=A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins. |journal=Chem. Senses |volume=31 |issue= 5 |pages= 445–52 |year= 2006 |pmid= 16565291 |doi= 10.1093/chemse/bjj049 }}
*{{cite journal  | author=Mashukova A, Spehr M, Hatt H, Neuhaus EM |title=Beta-arrestin2-mediated internalization of mammalian odorant receptors. |journal=J. Neurosci. |volume=26 |issue= 39 |pages= 9902-12 |year= 2006 |pmid= 17005854 |doi= 10.1523/JNEUROSCI.2897-06.2006 }}
*{{cite journal  | vauthors=Mashukova A, Spehr M, Hatt H, Neuhaus EM |title=Beta-arrestin2-mediated internalization of mammalian odorant receptors. |journal=J. Neurosci. |volume=26 |issue= 39 |pages= 9902–12 |year= 2006 |pmid= 17005854 |doi= 10.1523/JNEUROSCI.2897-06.2006 }}
}}
}}
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{{NLM content}}
{{NLM content}}
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{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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Latest revision as of 02:44, 27 October 2017

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Wikidata
View/Edit Human

Olfactory receptor 2AG1 is a protein that in humans is encoded by the OR2AG1 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: OR2AG1 olfactory receptor, family 2, subfamily AG, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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