OR6C2: Difference between revisions

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{{Infobox_gene}}
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'''Olfactory receptor 6C2''' is a [[protein]] that in humans is encoded by the ''OR6C2'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR6C2 olfactory receptor, family 6, subfamily C, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=341416| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 6, subfamily C, member 2
| HGNCid = 15436
| Symbol = OR6C2
| AltSymbols =; OR6C67
| OMIM = 
| ECnumber = 
| Homologene = 45066
| MGIid = 3030625
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 341416
    | Hs_Ensembl = ENSG00000179695
    | Hs_RefseqProtein = NP_473446
    | Hs_RefseqmRNA = NM_054105
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 54132265
    | Hs_GenLoc_end = 54133203
    | Hs_Uniprot = Q9NZP2
    | Mm_EntrezGene = 258932
    | Mm_Ensembl = ENSMUSG00000047626
    | Mm_RefseqmRNA = NM_146930
    | Mm_RefseqProtein = NP_667141
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 128929178
    | Mm_GenLoc_end = 128930116
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 6, subfamily C, member 2''', also known as '''OR6C2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR6C2 olfactory receptor, family 6, subfamily C, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=341416| accessdate = }}</ref>


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| section_title =  
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR6C2 olfactory receptor, family 6, subfamily C, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=341416| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal  | author=Rouquier S, Blancher A, Giorgi D |title=The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 6 |pages= 2870-4 |year= 2000 |pmid= 10706615 |doi= 10.1073/pnas.040580197 }}
*{{cite journal  |vauthors=Rouquier S, Blancher A, Giorgi D |title=The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 6 |pages= 2870–4 |year= 2000 |pmid= 10706615 |doi= 10.1073/pnas.040580197 | pmc=16022 }}
*{{cite journal  | author=Scherer SE, Muzny DM, Buhay CJ, ''et al.'' |title=The finished DNA sequence of human chromosome 12. |journal=Nature |volume=440 |issue= 7082 |pages= 346-51 |year= 2006 |pmid= 16541075 |doi= 10.1038/nature04569 }}
*{{cite journal  | author=Scherer SE |title=The finished DNA sequence of human chromosome 12 |journal=Nature |volume=440 |issue= 7082 |pages= 346–51 |year= 2006 |pmid= 16541075 |doi= 10.1038/nature04569 |name-list-format=vanc| author2=Muzny DM  | author3=Buhay CJ  | display-authors=3  | last4=Chen  | first4=Rui  | last5=Cree  | first5=Andrew  | last6=Ding  | first6=Yan  | last7=Dugan-Rocha  | first7=Shannon  | last8=Gill  | first8=Rachel  | last9=Gunaratne  | first9=Preethi }}
}}
}}
{{refend}}
{{refend}}


{== External links ==
== External links ==
* {{MeshName|OR6C2+protein,+human}}
* {{MeshName|OR6C2+protein,+human}}


{{NLM content}}
{{NLM content}}
{{membrane-protein-stub}}
 
{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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[[Category:Olfactory receptors]]
 
 
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Latest revision as of 02:50, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Olfactory receptor 6C2 is a protein that in humans is encoded by the OR6C2 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

  1. 1.0 1.1 "Entrez Gene: OR6C2 olfactory receptor, family 6, subfamily C, member 2".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.