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{{Infobox_gene}}
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'''Olfactory receptor 1N1''' is a [[protein]] that in humans is encoded by the ''OR1N1'' [[gene]].<ref name="pmid9500546">{{cite journal | vauthors = Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D | title = Distribution of olfactory receptor genes in the human genome | journal = Nat Genet | volume = 18 | issue = 3 | pages = 243–50 |date=Mar 1998 | pmid = 9500546 | pmc =  | doi = 10.1038/ng0398-243 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=138883| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 1, subfamily N, member 1
| HGNCid = 8221
| Symbol = OR1N1
| AltSymbols =; OR1-26; OR1N3; OR9-22
| OMIM = 
| ECnumber = 
| Homologene = 10583
| MGIid = 3030185
| GeneAtlas_image1 = PBB_GE_OR1N1_gnf1h10675_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
  | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 138883
    | Hs_Ensembl = ENSG00000171505
    | Hs_RefseqProtein = NP_036495
    | Hs_RefseqmRNA = NM_012363
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 124328458
    | Hs_GenLoc_end = 124329396
    | Hs_Uniprot = Q8NGS0
    | Mm_EntrezGene = 258944
    | Mm_Ensembl = ENSMUSG00000075383
    | Mm_RefseqmRNA = NM_146942
    | Mm_RefseqProtein = NP_667153
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 36681423
    | Mm_GenLoc_end = 36682355
    | Mm_Uniprot = 
  }}
}}
'''Olfactory receptor, family 1, subfamily N, member 1''', also known as '''OR1N1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=138883| accessdate = }}</ref>


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| section_title =  
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| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=138883| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal | author=Rouquier S, Taviaux S, Trask BJ, ''et al.'' |title=Distribution of olfactory receptor genes in the human genome. |journal=Nat. Genet. |volume=18 |issue= 3 |pages= 243-50 |year= 1998 |pmid= 9500546 |doi= 10.1038/ng0398-243 }}
*{{cite journal   |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 }}
*{{cite journal  | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
}}
}}
{{refend}}
{{refend}}
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{{NLM content}}
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{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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Latest revision as of 02:43, 27 October 2017

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External IDsGeneCards: [1]
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SpeciesHumanMouse
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RefSeq (mRNA)

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RefSeq (protein)

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Wikidata
View/Edit Human

Olfactory receptor 1N1 is a protein that in humans is encoded by the OR1N1 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

See also

References

  1. ↑ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  2. ↑ 2.0 2.1 "Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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