OR13H1: Difference between revisions

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{{Infobox_gene}}
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'''Olfactory receptor 13H1''' is a [[protein]] that in humans is encoded by the ''OR13H1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=347468| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Olfactory receptor, family 13, subfamily H, member 1
| HGNCid = 14755
| Symbol = OR13H1
| AltSymbols =; ORX1
| OMIM = 
| ECnumber = 
| Homologene = 27122
| MGIid = 1333887
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 347468
    | Hs_Ensembl = ENSG00000171054
    | Hs_RefseqProtein = NP_001004486
    | Hs_RefseqmRNA = NM_001004486
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 130505729
    | Hs_GenLoc_end = 130506655
    | Hs_Uniprot = Q8NG92
    | Mm_EntrezGene = 18363
    | Mm_Ensembl = ENSMUSG00000043698
    | Mm_RefseqmRNA = NM_146315
    | Mm_RefseqProtein = NP_666427
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 118150811
    | Mm_GenLoc_end = 118164398
    | Mm_Uniprot = 
  }}
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'''Olfactory receptor, family 13, subfamily H, member 1''', also known as '''OR13H1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=347468| accessdate = }}</ref>


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| section_title =  
| section_title =  
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=347468| accessdate = }}</ref>
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal   |vauthors=Parmentier M, Libert F, Schurmans S, etal |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells |journal=Nature |volume=355 |issue= 6359 |pages= 453–5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal  | author=Buck L, Axel R |title=A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. |journal=Cell |volume=65 |issue= 1 |pages= 175-87 |year= 1991 |pmid= 1840504 |doi=  }}
*{{cite journal  | vauthors=Buck L, Axel R |title=A novel multigene family may encode odorant receptors: a molecular basis for odor recognition |journal=Cell |volume=65 |issue= 1 |pages= 175–87 |year= 1991 |pmid= 1840504 |doi=10.1016/0092-8674(91)90418-X }}
*{{cite journal  | author=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. |journal=Biochem. Biophys. Res. Commun. |volume=237 |issue= 2 |pages= 283-7 |year= 1997 |pmid= 9268701 |doi= 10.1006/bbrc.1997.7043 }}
*{{cite journal  | vauthors=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome |journal=Biochem. Biophys. Res. Commun. |volume=237 |issue= 2 |pages= 283–7 |year= 1997 |pmid= 9268701 |doi= 10.1006/bbrc.1997.7043 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal   |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830 }}
*{{cite journal  | author=Gilad Y, Bustamante CD, Lancet D, Pääbo S |title=Natural selection on the olfactory receptor gene family in humans and chimpanzees. |journal=Am. J. Hum. Genet. |volume=73 |issue= 3 |pages= 489-501 |year= 2003 |pmid= 12908129 |doi= 10.1086/378132 }}
*{{cite journal  | vauthors=Gilad Y, Bustamante CD, Lancet D, Pääbo S |title=Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees |journal=Am. J. Hum. Genet. |volume=73 |issue= 3 |pages= 489–501 |year= 2003 |pmid= 12908129 |doi= 10.1086/378132 | pmc=1180675 }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993 }}
*{{cite journal | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
*{{cite journal   |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 }}
}}
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{{NLM content}}
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{{Olfactory receptors}}
{{Olfactory receptors}}
[[Category:G protein coupled receptors]]
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Latest revision as of 00:28, 7 September 2017

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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RefSeq (mRNA)

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Wikidata
View/Edit Human

Olfactory receptor 13H1 is a protein that in humans is encoded by the OR13H1 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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