Cholangiocarcinoma classification: Difference between revisions
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Cholangiocarcinoma may be classified according to location of the tumor into three subtypes: extrahepatic bile duct cancer, perihilar bile duct cancer, and intrahepatic bile duct cancer.<ref>{{cite journal |author=KLATSKIN G |title=ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES |journal=Am J Med |volume=38 |issue= |pages=241-56 |year= |pmid=14256720}}</ref> Perihilar cholangiocarcinoma may be classified according to Bismuth-Corlette classification into five subtypes based on the extent of ductal infiltration. | Cholangiocarcinoma may be classified according to location of the tumor into three subtypes: extrahepatic bile duct cancer, perihilar bile duct cancer, and intrahepatic bile duct cancer.<ref>{{cite journal |author=KLATSKIN G |title=ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES |journal=Am J Med |volume=38 |issue= |pages=241-56 |year= |pmid=14256720}}</ref> Perihilar cholangiocarcinoma may be classified according to Bismuth-Corlette classification into five subtypes based on the extent of ductal infiltration. | ||
==Classification== | ==Classification== | ||
Cholangiocarcinoma may be classified according to location of the tumor into three subtypes:<ref>{{cite journal | | Cholangiocarcinoma may be classified according to location of the tumor into three subtypes:<ref name="pmid17457168">{{cite journal |vauthors=DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD |title=Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution |journal=Ann. Surg. |volume=245 |issue=5 |pages=755–62 |year=2007 |pmid=17457168 |pmc=1877058 |doi=10.1097/01.sla.0000251366.62632.d3 |url=}}</ref> | ||
*Extrahepatic bile duct cancer | *Extrahepatic bile duct cancer | ||
*Perihilar bile duct cancer | *Perihilar bile duct cancer |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Cholangiocarcinoma may be classified according to location of the tumor into three subtypes: extrahepatic bile duct cancer, perihilar bile duct cancer, and intrahepatic bile duct cancer.[1] Perihilar cholangiocarcinoma may be classified according to Bismuth-Corlette classification into five subtypes based on the extent of ductal infiltration.
Classification
Cholangiocarcinoma may be classified according to location of the tumor into three subtypes:[2]
- Extrahepatic bile duct cancer
- Perihilar bile duct cancer
- Intrahepatic bile duct cancer
Cellular Classification of Cholangiocarcinoma
Extrahepatic Bile Duct Cancer
- Carcinoma in situ
- Adenocarcinoma, not otherwise specified (NOS)
- Adenocarcinoma
- Intestinal type
- Mucinous type
- Clear cell type
- Signet-ring cell carcinoma
- Adenosquamous carcinoma
- Squamous cell carcinoma
- Small cell (oat cell) carcinoma
- Undifferentiated carcinoma
- Spindle cell type
- Giant cell type
- Small cell type
- Papillomatosis
- Papillary carcinoma
- Noninvasive
- Papillary carcinoma
- Invasive
- Carcinoma, NOS
Perihilar Bile Duct Cancer
- Carcinoma in situ
- Adenocarcinoma, not otherwise specified (NOS)
- Adenocarcinoma
- Intestinal type
- Mucinous type
- Clear cell type
- Signet-ring cell carcinoma
- Adenosquamous carcinoma
- Squamous cell carcinoma
- Small cell (oat cell) carcinoma
- Undifferentiated carcinoma
- Spindle cell type
- Giant cell type
- Small cell type
- Papillomatosis
- Papillary carcinoma
- Noninvasive
- Invasive
- Carcinoma, NOS
Intrahepatic Bile Duct Cancer
- Mass-forming tumor growth pattern
- Periductal-infiltrating tumor growth pattern
- Mixed mass-forming and periductal-infiltrating growth pattern
Bismuth-Corlette classification
Perihilar cholangiocarcinoma may be classified according to Bismuth-Corlette classification into five subtypes based on the extent of ductal infiltration:[3]
Type I: Limited to the common hepatic duct, below the level of the confluence of the right and left hepatic ducts
Type II: Involves the confluence of the right and left hepatic ducts
Type IIIa: Type II and extends to the bifurcation of the right hepatic duct
Type IIIb: Type II and extends to the bifurcation of the left hepatic duct
Type IV: Extending to the bifurcations of both right and left hepatic duct or multifocal involvement
Type V: Stricture at the junction of common bile duct and cystic duct
References
- ↑ KLATSKIN G. "ADENOCARCINOMA OF THE HEPATIC DUCT AT ITS BIFURCATION WITHIN THE PORTA HEPATIS. AN UNUSUAL TUMOR WITH DISTINCTIVE CLINICAL AND PATHOLOGICAL FEATURES". Am J Med. 38: 241–56. PMID 14256720.
- ↑ DeOliveira ML, Cunningham SC, Cameron JL, Kamangar F, Winter JM, Lillemoe KD, Choti MA, Yeo CJ, Schulick RD (2007). "Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution". Ann. Surg. 245 (5): 755–62. doi:10.1097/01.sla.0000251366.62632.d3. PMC 1877058. PMID 17457168.
- ↑ Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/bismuth-corlette-classification