Idiopathic pulmonary fibrosis risk factors: Difference between revisions
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** Gastroesophageal Reflux Disease (GERD): | ** Gastroesophageal Reflux Disease (GERD): | ||
*** GERD | *** GERD | ||
** Gene mutations | ** Gene mutations: | ||
** | *** Genetic mutations showed increase risk in development of pulmonary fibrosis. Mutations include the following genes:<ref name="pmid29413083">{{cite journal| author=Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G et al.| title=Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? | journal=Lancet Respir Med | year= 2018 | volume= 6 | issue= 2 | pages= 154-160 | pmid=29413083 | doi=10.1016/S2213-2600(18)30007-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29413083 }}</ref> | ||
**** ''hTERT'' and ''hTR'' | |||
**** ''MUC5B'' | |||
**** ''TERT '' | |||
**** ''TERC '' | |||
**** ''RTEL1 '' | |||
**** ''PARN '' | |||
**** ''DKC1 '' | |||
**** ''TINF2 '' | |||
**** ''SFTPC'' | |||
**** ''SFTPA2'' | |||
**** ''ABCA3'' | |||
==References== | ==References== |
Revision as of 19:01, 13 February 2018
Idiopathic pulmonary fibrosis Microchapters |
Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Risk Factors
Common risk factors
- Common risk factors of idiopathic pulmonary fibrosis include the following:
- Cigarette smoking:[1]
- Is the most important risk factor for idiopathic pulmonary fibrosis even years after cessation
- Gastroesophageal Reflux Disease (GERD):
- GERD
- Gene mutations:
- Genetic mutations showed increase risk in development of pulmonary fibrosis. Mutations include the following genes:[2]
- hTERT and hTR
- MUC5B
- TERT
- TERC
- RTEL1
- PARN
- DKC1
- TINF2
- SFTPC
- SFTPA2
- ABCA3
- Genetic mutations showed increase risk in development of pulmonary fibrosis. Mutations include the following genes:[2]
- Cigarette smoking:[1]
References
- ↑ Baumgartner KB, Samet JM, Stidley CA, Colby TV, Waldron JA (1997). "Cigarette smoking: a risk factor for idiopathic pulmonary fibrosis". Am J Respir Crit Care Med. 155 (1): 242–8. doi:10.1164/ajrccm.155.1.9001319. PMID 9001319.
- ↑ Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G; et al. (2018). "Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?". Lancet Respir Med. 6 (2): 154–160. doi:10.1016/S2213-2600(18)30007-9. PMID 29413083.