Idiopathic pulmonary fibrosis risk factors: Difference between revisions
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*** GERD | *** GERD | ||
** Gene mutations: | ** Gene mutations: | ||
*** Genetic mutations showed increase risk in development of pulmonary fibrosis. Mutations include the following genes:<ref name="pmid29413083">{{cite journal| author=Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G et al.| title=Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? | journal=Lancet Respir Med | year= 2018 | volume= 6 | issue= 2 | pages= 154-160 | pmid=29413083 | doi=10.1016/S2213-2600(18)30007-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29413083 }}</ref> | *** Genetic mutations showed increase risk in development of pulmonary fibrosis. Mutations include the following genes:<ref name="pmid29413083">{{cite journal| author=Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G et al.| title=Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? | journal=Lancet Respir Med | year= 2018 | volume= 6 | issue= 2 | pages= 154-160 | pmid=29413083 | doi=10.1016/S2213-2600(18)30007-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29413083 }}</ref><ref name="ArmaniosChen2007">{{cite journal|last1=Armanios|first1=Mary Y.|last2=Chen|first2=Julian J.-L.|last3=Cogan|first3=Joy D.|last4=Alder|first4=Jonathan K.|last5=Ingersoll|first5=Roxann G.|last6=Markin|first6=Cheryl|last7=Lawson|first7=William E.|last8=Xie|first8=Mingyi|last9=Vulto|first9=Irma|last10=Phillips|first10=John A.|last11=Lansdorp|first11=Peter M.|last12=Greider|first12=Carol W.|last13=Loyd|first13=James E.|title=Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis|journal=New England Journal of Medicine|volume=356|issue=13|year=2007|pages=1317–1326|issn=0028-4793|doi=10.1056/NEJMoa066157}}</ref> | ||
**** ''hTERT'' and ''hTR'' | **** ''hTERT'' and ''hTR'' | ||
**** ''MUC5B'' | **** ''MUC5B'' | ||
**** ''TERT '' | **** ''TERT '' | ||
**** ''TERC '' | **** ''TERC '' | ||
Revision as of 19:05, 13 February 2018
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Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Risk Factors
Common risk factors
- Common risk factors of idiopathic pulmonary fibrosis include the following:
- Cigarette smoking:[1]
- Is the most important risk factor for idiopathic pulmonary fibrosis even years after cessation
- Gastroesophageal Reflux Disease (GERD):
- GERD
- Gene mutations:
- Cigarette smoking:[1]
References
- ↑ Baumgartner KB, Samet JM, Stidley CA, Colby TV, Waldron JA (1997). "Cigarette smoking: a risk factor for idiopathic pulmonary fibrosis". Am J Respir Crit Care Med. 155 (1): 242–8. doi:10.1164/ajrccm.155.1.9001319. PMID 9001319.
- ↑ Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G; et al. (2018). "Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?". Lancet Respir Med. 6 (2): 154–160. doi:10.1016/S2213-2600(18)30007-9. PMID 29413083.
- ↑ Armanios, Mary Y.; Chen, Julian J.-L.; Cogan, Joy D.; Alder, Jonathan K.; Ingersoll, Roxann G.; Markin, Cheryl; Lawson, William E.; Xie, Mingyi; Vulto, Irma; Phillips, John A.; Lansdorp, Peter M.; Greider, Carol W.; Loyd, James E. (2007). "Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis". New England Journal of Medicine. 356 (13): 1317–1326. doi:10.1056/NEJMoa066157. ISSN 0028-4793.