Multiple sclerosis risk factors: Difference between revisions
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==== Genetic ==== | ==== Genetic ==== | ||
Some studies demonstrate that [[MS]] has a strong genetic base. The first degree family of a [[MS]] patient is at 10-25 times greater risk than normal population, so genetically susceptible people are more likely to developed [[MS]] disease. | Some studies demonstrate that [[MS]] has a strong genetic base. The first degree family of a [[MS]] patient is at 10-25 times greater risk than normal population, so genetically susceptible people are more likely to developed [[MS]] disease.<ref name="pmid8800940">{{cite journal |vauthors=Robertson NP, Fraser M, Deans J, Clayton D, Walker N, Compston DA |title=Age-adjusted recurrence risks for relatives of patients with multiple sclerosis |journal=Brain |volume=119 ( Pt 2) |issue= |pages=449–55 |date=April 1996 |pmid=8800940 |doi= |url=}}</ref><ref name="pmid3376997">{{cite journal |vauthors=Sadovnick AD, Baird PA, Ward RH |title=Multiple sclerosis: updated risks for relatives |journal=Am. J. Med. Genet. |volume=29 |issue=3 |pages=533–41 |date=March 1988 |pmid=3376997 |doi=10.1002/ajmg.1320290310 |url=}}</ref> | ||
==References== | ==References== | ||
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Overview
Risk Factors
Common environmental risk factors in the development of multiple sclerosis are smoking[1], genetic, occupational exposures and toxins, physical environment and stress.[2]
smoking
various studies showed that smoking, beside cardiovascular diseases and cancer, can be a risk factor of multiple sclerosis.[1][3]
Genetic
Some studies demonstrate that MS has a strong genetic base. The first degree family of a MS patient is at 10-25 times greater risk than normal population, so genetically susceptible people are more likely to developed MS disease.[4][5]
References
- ↑ 1.0 1.1 Riise T, Nortvedt MW, Ascherio A (October 2003). "Smoking is a risk factor for multiple sclerosis". Neurology. 61 (8): 1122–4. PMID 14581676.
- ↑ Coo H, Aronson KJ (2004). "A systematic review of several potential non-genetic risk factors for multiple sclerosis". Neuroepidemiology. 23 (1–2): 1–12. doi:10.1159/000073969. PMID 14739563.
- ↑ Hernán MA, Olek MJ, Ascherio A (July 2001). "Cigarette smoking and incidence of multiple sclerosis". Am. J. Epidemiol. 154 (1): 69–74. PMID 11427406.
- ↑ Robertson NP, Fraser M, Deans J, Clayton D, Walker N, Compston DA (April 1996). "Age-adjusted recurrence risks for relatives of patients with multiple sclerosis". Brain. 119 ( Pt 2): 449–55. PMID 8800940.
- ↑ Sadovnick AD, Baird PA, Ward RH (March 1988). "Multiple sclerosis: updated risks for relatives". Am. J. Med. Genet. 29 (3): 533–41. doi:10.1002/ajmg.1320290310. PMID 3376997.