Large cell carcinoma of the lung causes: Difference between revisions
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==Common Causes== | ==Common Causes== | ||
*Common causes of large cell carcinoma of the lung include precursor lesions, such as metaplasia or dysplasia. | *Common causes of large cell carcinoma of the lung include precursor lesions, such as metaplasia or dysplasia.<ref name="pmid9232332">{{cite journal |vauthors=Muscat JE, Stellman SD, Zhang ZF, Neugut AI, Wynder EL |title=Cigarette smoking and large cell carcinoma of the lung |journal=Cancer Epidemiol. Biomarkers Prev. |volume=6 |issue=7 |pages=477–80 |date=July 1997 |pmid=9232332 |doi= |url=}}</ref> | ||
*Precursor lesions of large cell carcinoma of the lung, include:<ref name="NSCL">National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015</ref> | *Precursor lesions of large cell carcinoma of the lung, include:<ref name="NSCL">National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015</ref><ref name="pmid26039012">{{cite journal |vauthors=Fasano M, Della Corte CM, Papaccio F, Ciardiello F, Morgillo F |title=Pulmonary Large-Cell Neuroendocrine Carcinoma: From Epidemiology to Therapy |journal=J Thorac Oncol |volume=10 |issue=8 |pages=1133–41 |date=August 2015 |pmid=26039012 |pmc=4503246 |doi=10.1097/JTO.0000000000000589 |url=}}</ref> | ||
:*Smoking (active/passive) | :*Smoking (active/passive) | ||
:*Asbestos exposure | :*Asbestos exposure | ||
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==Less Common Causes== | ==Less Common Causes== | ||
*Less common causes of large cell carcinoma of the lung, include:<ref name="NSCL">National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015</ref> | *Less common causes of large cell carcinoma of the lung, include:<ref name="NSCL">National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015</ref><ref name="pmid9404741">{{cite journal |vauthors=Barbone F, Bovenzi M, Cavallieri F, Stanta G |title=Cigarette smoking and histologic type of lung cancer in men |journal=Chest |volume=112 |issue=6 |pages=1474–9 |date=December 1997 |pmid=9404741 |doi= |url=}}</ref> | ||
:*Inorganic arsenic exposure | :*Inorganic arsenic exposure | ||
:*Chromium, nickel exposure | :*Chromium, nickel exposure |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Causes of large cell carcinoma of the lung, are those of non-small cell lung cancers. Common causes include precursor lesions, such as metaplasia or dysplasia induced by smoking, asbestos exposure, ionizing radiation, atmospheric pollution, and chronic interstitial pneumonitis. Less common causes of large cell carcinoma of the lung include chromium and nickel exposure, vinyl chloride exposure, and inorganic arsenic exposure.
Common Causes
- Common causes of large cell carcinoma of the lung include precursor lesions, such as metaplasia or dysplasia.[1]
- Precursor lesions of large cell carcinoma of the lung, include:[2][3]
- Smoking (active/passive)
- Asbestos exposure
- Chronic interstitial pneumonitis
- Ionizing radiation
- Atmospheric pollution
Less Common Causes
- Inorganic arsenic exposure
- Chromium, nickel exposure
- Vinyl chloride exposure
- Radon exposure
- Halogen ether exposure
References
- ↑ Muscat JE, Stellman SD, Zhang ZF, Neugut AI, Wynder EL (July 1997). "Cigarette smoking and large cell carcinoma of the lung". Cancer Epidemiol. Biomarkers Prev. 6 (7): 477–80. PMID 9232332.
- ↑ 2.0 2.1 National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015
- ↑ Fasano M, Della Corte CM, Papaccio F, Ciardiello F, Morgillo F (August 2015). "Pulmonary Large-Cell Neuroendocrine Carcinoma: From Epidemiology to Therapy". J Thorac Oncol. 10 (8): 1133–41. doi:10.1097/JTO.0000000000000589. PMC 4503246. PMID 26039012.
- ↑ Barbone F, Bovenzi M, Cavallieri F, Stanta G (December 1997). "Cigarette smoking and histologic type of lung cancer in men". Chest. 112 (6): 1474–9. PMID 9404741.