Multiple sclerosis other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
====Evoked | ====Evoked potential studies==== | ||
The brain of a person with MS often responds less actively to stimulation of the [[optic nerve]] and [[sensory neuron|sensory nerves]]. These brain responses can be examined using [[visual evoked potential]]s (VEPs) and [[Sensory evoked potentials|somatosensory evoked potentials]] (SEPs). Decreased activity on either test can reveal demyelination which may be otherwise asymptomatic. Along with other data, these exams can help find the widespread nerve involvement required for a definite diagnosis of MS.<ref>Gronseth GS; Ashman EJ. ''Practice parameter: the usefulness of evoked potentials in identifying clinically silent lesions in patients with suspected multiple sclerosis (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology.'' Neurology 2000 May 9;54(9):1720–5. PMID 10802774</ref> | The brain of a person with MS often responds less actively to stimulation of the [[optic nerve]] and [[sensory neuron|sensory nerves]]. These brain responses can be examined using [[visual evoked potential]]s (VEPs) and [[Sensory evoked potentials|somatosensory evoked potentials]] (SEPs). Decreased activity on either test can reveal demyelination which may be otherwise asymptomatic. Along with other data, these exams can help find the widespread nerve involvement required for a definite diagnosis of MS.<ref>Gronseth GS; Ashman EJ. ''Practice parameter: the usefulness of evoked potentials in identifying clinically silent lesions in patients with suspected multiple sclerosis (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology.'' Neurology 2000 May 9;54(9):1720–5. PMID 10802774</ref> | ||
==== Antimyelin antibodies ==== | |||
[[myelin oligodendrocyte glycoprotein]] ([[Myelin oligodendrocyte glycoprotein|MOG]]) and [[myelin basic protein]] ([[Myelin basic protein|MBP]]) thought to be a predictor of [[disease]] progression but some studies denied any relationship between these auto [[antibodies]] and [[disease]] severity or progression. | |||
==References== | ==References== | ||
Revision as of 13:26, 1 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Other Diagnostic Studies
Evoked potential studies
The brain of a person with MS often responds less actively to stimulation of the optic nerve and sensory nerves. These brain responses can be examined using visual evoked potentials (VEPs) and somatosensory evoked potentials (SEPs). Decreased activity on either test can reveal demyelination which may be otherwise asymptomatic. Along with other data, these exams can help find the widespread nerve involvement required for a definite diagnosis of MS.[1]
Antimyelin antibodies
myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP) thought to be a predictor of disease progression but some studies denied any relationship between these auto antibodies and disease severity or progression.
References
- ↑ Gronseth GS; Ashman EJ. Practice parameter: the usefulness of evoked potentials in identifying clinically silent lesions in patients with suspected multiple sclerosis (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2000 May 9;54(9):1720–5. PMID 10802774