Idiopathic pulmonary fibrosis surgery: Difference between revisions
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=== Lung transplantation === | === Lung transplantation === | ||
* Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.<ref name="pmid12928646">{{cite journal| author=Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R et al.| title=Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis. | journal=J Thorac Cardiovasc Surg | year= 2003 | volume= 126 | issue= 2 | pages= 469-75 | pmid=12928646 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12928646 }}</ref> | * Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.<ref name="pmid12928646">{{cite journal| author=Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R et al.| title=Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis. | journal=J Thorac Cardiovasc Surg | year= 2003 | volume= 126 | issue= 2 | pages= 469-75 | pmid=12928646 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12928646 }}</ref> | ||
* | * Time of referral to lung transplantation: <ref name="pmid25085497">{{cite journal| author=Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S et al.| title=A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation. | journal=J Heart Lung Transplant | year= 2015 | volume= 34 | issue= 1 | pages= 1-15 | pmid=25085497 | doi=10.1016/j.healun.2014.06.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25085497 }}</ref> | ||
** Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function | |||
** Forced vital capacity (FVC) <80% predicted | |||
** Diffusion capacity of the lung for carbon monoxide (Dlco) <40% predicted. | |||
** Lung functional limitation (eg, dyspnea) | |||
* Time of listing:<ref name="pmid250854972">{{cite journal| author=Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S et al.| title=A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation. | journal=J Heart Lung Transplant | year= 2015 | volume= 34 | issue= 1 | pages= 1-15 | pmid=25085497 | doi=10.1016/j.healun.2014.06.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25085497 }}</ref> | |||
** Decline in FVC ≥10% during 6 months of follow-up | |||
** Decline in Dlco ≥15% during 6 months of follow-up | |||
** Pulmonary hypertension development | |||
** Hospitalization due to acute exacerbation | |||
* Indications of lung transplant include the following: | |||
** Patients younger than 65 years old | ** Patients younger than 65 years old | ||
** Patients with low body mass index (<26 kg/m<sup>2</sup>) | ** Patients with low body mass index (<26 kg/m<sup>2</sup>) | ||
Revision as of 19:15, 21 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
Lung transplantation
- Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.[1]
- Time of referral to lung transplantation: [2]
- Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function
- Forced vital capacity (FVC) <80% predicted
- Diffusion capacity of the lung for carbon monoxide (Dlco) <40% predicted.
- Lung functional limitation (eg, dyspnea)
- Time of listing:[3]
- Decline in FVC ≥10% during 6 months of follow-up
- Decline in Dlco ≥15% during 6 months of follow-up
- Pulmonary hypertension development
- Hospitalization due to acute exacerbation
- Indications of lung transplant include the following:
- Patients younger than 65 years old
- Patients with low body mass index (<26 kg/m2)
References
- ↑ Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R; et al. (2003). "Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis". J Thorac Cardiovasc Surg. 126 (2): 469–75. PMID 12928646.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.