Antiphospholipid syndrome causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Antiphospholipid syndrome}} | {{Antiphospholipid syndrome}} | ||
{{CMG}} | {{CMG}}{{AE}}{{FT}} | ||
==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
The causes of antiphospholipid syndrome are as follows: | |||
{| class="wikitable" | |||
!Autoimmune diseases | |||
!Infections | |||
!Drugs | |||
!Malignancy | |||
|- | |||
| | |||
* Systemic lupus erythmatosus(SLE) | |||
|'''Bacterial infections:''' | |||
* Leptospirosis<ref name="pmid1853785">{{cite journal| author=McNeil HP, Chesterman CN, Krilis SA| title=Immunology and clinical importance of antiphospholipid antibodies. | journal=Adv Immunol | year= 1991 | volume= 49 | issue= | pages= 193-280 | pmid=1853785 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1853785 }} </ref><ref name="pmid10477458">{{cite journal| author=Safa O, Crippa L, Della Valle P, Sabbadini MG, Viganò D'Angelo S, D'Angelo A| title=IgG reactivity to phospholipid-bound beta(2)-glycoprotein I is the main determinant of the fraction of lupus anticoagulant activity quenched by addition of hexagonal (II) phase phospholipid in patients with the clinical suspicion of antiphospholipid-antibody syndrome. | journal=Haematologica | year= 1999 | volume= 84 | issue= 9 | pages= 829-38 | pmid=10477458 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10477458 }} </ref> | |||
* Syphilis | |||
* Lymes disease | |||
* Tuberculosis<ref name="pmid9814666">{{cite journal| author=Triplett DA| title=Many faces of lupus anticoagulants. | journal=Lupus | year= 1998 | volume= 7 Suppl 2 | issue= | pages= S18-22 | pmid=9814666 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9814666 }} </ref> | |||
* Leprosy | |||
* Infective endocarditis | |||
* Post-Streptococcal rheumatic fever | |||
* Klebsiella infection | |||
'''Viral infections:''' | |||
* Hepatitis A,B and C | |||
* HIV | |||
* Ebstein Barr virus | |||
* Adenovirus | |||
* Rubella | |||
* Parvovirus | |||
* Cytomegalovirus | |||
* Varicella Zoster virus | |||
'''Parasitic infections:''' | |||
* Visceral leischmaniasis | |||
* Pneumocysitis jirovecci | |||
* Malaria | |||
| | |||
* Chlorpromazine | |||
* Procainamide | |||
* Hydralazine | |||
* Quinidine | |||
* Quinine | |||
* Phenytoin | |||
* Alpha interferon | |||
* Oral contraceptives | |||
* Amoxicillin | |||
* Chlorothiazide | |||
* Propanolol | |||
|Tumors of the following organs can cause APS: | |||
* Lung | |||
* Colon | |||
* Breast | |||
* Cervix | |||
* Ovary | |||
'''Cancers:''' | |||
* Hodgkins lymphoma | |||
* Non-hodgkins lymphoma | |||
* Myeloid leukemia | |||
* Lymphocytic leukemia | |||
* Primary myelofibrosis | |||
* Polycythemia vera | |||
|} | |||
==References== | ==References== | ||
Revision as of 20:45, 27 March 2018
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Antiphospholipid syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Causes
The causes of antiphospholipid syndrome are as follows:
| Autoimmune diseases | Infections | Drugs | Malignancy |
|---|---|---|---|
|
Bacterial infections:
Viral infections:
Parasitic infections:
|
|
Tumors of the following organs can cause APS:
Cancers:
|
References
- ↑ McNeil HP, Chesterman CN, Krilis SA (1991). "Immunology and clinical importance of antiphospholipid antibodies". Adv Immunol. 49: 193–280. PMID 1853785.
- ↑ Safa O, Crippa L, Della Valle P, Sabbadini MG, Viganò D'Angelo S, D'Angelo A (1999). "IgG reactivity to phospholipid-bound beta(2)-glycoprotein I is the main determinant of the fraction of lupus anticoagulant activity quenched by addition of hexagonal (II) phase phospholipid in patients with the clinical suspicion of antiphospholipid-antibody syndrome". Haematologica. 84 (9): 829–38. PMID 10477458.
- ↑ Triplett DA (1998). "Many faces of lupus anticoagulants". Lupus. 7 Suppl 2: S18–22. PMID 9814666.