Antiphospholipid syndrome risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Risk Factors

The Antiphospholipid syndrome risk factors are as follows:

• Common risk factors
  • History of autoimmune diseases like SLE, Sjogren's syndrome etc.
  • Infections-Cytomegalovirus, Human Immunodeficiency Virus, Parvovirus B-19, Hepatitis C Virus, Lymes, Syphilis, E.coli, Leptospirosis.
  • Drugs- Hydralazine, Quinidine, Phenytoin, and Amoxicillin
  • Family history- antiphospholipid syndrome is common in patients with a family history of antiphospholipid syndrome.

• Less common causes
  • Pregnancy
  • Obesity
  • Hypertension
  • Sedentary lifestyle
  • Recent surgery
  • Tobacco Smoking
  • Oral contraceptives
  • Estrogen therapy
  • Hyperlipidemias
  • Cancer