Ankylosing spondylitis laboratory findings: Difference between revisions

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==Overview==
==Overview==
There is no direct test to diagnose ankylosing spondylitis, however there is an increase of [[C-Reactive protein|C-reactive protein]] (CRP) and an increase in the [[erythrocyte sedimentation rate]] (ESR).
There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS).There are certain blood tests that can check for markers of inflammation.Most of the time patients with AS their blood is tested for the HLA-B27 gene, but again most people who are positive for that gene don't have ankylosing spondylitis.Other laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.


==Laboratory Findings==
==Laboratory Findings==
* There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS) and most the tests are non-specific.
* Human leukocyte antigen (HLA)-B27 is positive in most the patients, but not invariably so.<ref name="pmid27586785">{{cite journal |vauthors=de Winter JJ, van Mens LJ, van der Heijde D, Landewé R, Baeten DL |title=Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis |journal=Arthritis Res. Ther. |volume=18 |issue= |pages=196 |date=September 2016 |pmid=27586785 |pmc=5009714 |doi=10.1186/s13075-016-1093-z |url=}}</ref>
* laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.
[[Image:Ankylosing process.jpg|center|thumb|256px|The ankylosis process.]]  
[[Image:Ankylosing process.jpg|center|thumb|256px|The ankylosis process.]]  
Increase in:
Increase in:

Revision as of 14:37, 6 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS).There are certain blood tests that can check for markers of inflammation.Most of the time patients with AS their blood is tested for the HLA-B27 gene, but again most people who are positive for that gene don't have ankylosing spondylitis.Other laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.

Laboratory Findings

  • There are no specific diagnostic laboratory findings associated with ankylosing spondylitis(AS) and most the tests are non-specific.
  • Human leukocyte antigen (HLA)-B27 is positive in most the patients, but not invariably so.[1]
  • laboratory findings consistent with ankylosing spondylitis(AS) include ESR and CRP levels.
The ankylosis process.

Increase in:

References

  1. de Winter JJ, van Mens LJ, van der Heijde D, Landewé R, Baeten DL (September 2016). "Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis". Arthritis Res. Ther. 18: 196. doi:10.1186/s13075-016-1093-z. PMC 5009714. PMID 27586785.

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