Ankylosing spondylitis differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Ankylosing spondylitis needs to be differentiated from certain conditions such as a strain of the | Ankylosing spondylitis needs to be differentiated from certain conditions such as a strain of the psoriatic arthritis,rheumatoid arthritis and reactive arthritis. | ||
==Differentiating Ankylosing spondylitis from other Diseases== | ==Differentiating Ankylosing spondylitis from other Diseases== | ||
<small> | * Ankylosing spondylitis must be differentiated from other diseases causing [[Oligoarthritis|oligo]]/[[polyarthritis]] or [[arthritis]] of the [[axial skeleton]], including:<small> {| class="wikitable" ! align="center" style="background:#4479BA; color: #FFFFFF;" + |Arthritis Type ! colspan="7" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Clinical Features ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Body Distribution ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Key Signs ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Laboratory Abnormalities |- | |'''History of Psoriasis''' |'''Symmetric [[joint]] involvement''' |'''Asymmetric [[joint]] involvement''' |[[Enthesopathy|'''Enthesopathy''']] |'''[[Dactylitis]]''' |'''[[Nail (anatomy)|Nail]] [[Dystrophy]]''' |'''[[Human Immunodeficiency Virus (HIV)|Human immunodeficiency virus]] association''' |'''[[Upper extremity]]-hands''' |'''[[Lower extremity]]''' |'''[[Sacroiliac joint|Sacroiliac joints]]''' |'''[[Spine]]''' |'''[[Osteopenia]]''' |'''[[Joint]] Space''' |'''[[Ankylosis]]''' |'''[[Periostitis]]''' |'''[[Soft tissue]] swelling''' |'''[[ESR]]''' |'''[[Rheumatoid factor]] ([[Rheumatoid factor|RF]])''' |'''[[HLA-B27]]''' |- |'''[[Psoriatic arthritis]]''' | + | + | ++ | + | + | + | + | +++ ([[Distal interphalangeal joints|DIP]]/[[Proximal interphalangeal joints|PIP]]) | +++ | ++ (Unilateral) | ++ | - | ++ (Widening) | ++ | +++ (Fluffy) | ++ | + | - |30-75% |- |'''[[Rheumatoid arthritis]]''' | - | ++ | + | - | - | - | - | +++ ([[MCP joints|MCP]]/[[wrist]]) | +++ | + (Unilateral) | ++([[Cervical spine|Cervical]]) | +++ | +++ (Narrowing) | + | + (Linear) | +++ | +++ | +++ |6-8% |- |'''[[Ankylosing spondylitis]]''' | - | +++ | - | + | - | - | - | + | + | +++ (Bilateral) | +++ | +++ | ++ (Narrowing) | +++ | +++ (Fluffy) | + | +++ | - |90% |- |'''[[Reactive arthritis]] ([[Reiter's syndrome]])''' | - | +++ | - | + | + | - | - | ++ | +++ | ++ (Unilateral) | + | + | + (Narrowing) | - | +++ (Fluffy) | ++ | ++ | - |75% |} Key:+ : Infrequently present, ++ : Frequently present, +++ : Always present, - : Absent ==References== | ||
{| class="wikitable" | |||
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Arthritis Type | |||
! colspan="7" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Clinical Features | |||
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Body Distribution | |||
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Key Signs | |||
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Laboratory Abnormalities | |||
|- | |||
| | |||
|'''History of Psoriasis''' | |||
|'''Symmetric [[joint]] involvement''' | |||
|'''Asymmetric [[joint]] involvement''' | |||
|[[Enthesopathy|'''Enthesopathy''']] | |||
|'''[[Dactylitis]]''' | |||
|'''[[Nail (anatomy)|Nail]] [[Dystrophy]]''' | |||
|'''[[Human Immunodeficiency Virus (HIV)|Human immunodeficiency virus]] association''' | |||
|'''[[Upper extremity]]-hands''' | |||
|'''[[Lower extremity]]''' | |||
|'''[[Sacroiliac joint|Sacroiliac joints]]''' | |||
|'''[[Spine]]''' | |||
|'''[[Osteopenia]]''' | |||
|'''[[Joint]] Space''' | |||
|'''[[Ankylosis]]''' | |||
|'''[[Periostitis]]''' | |||
|'''[[Soft tissue]] swelling''' | |||
|'''[[ESR]]''' | |||
|'''[[Rheumatoid factor]] ([[Rheumatoid factor|RF]])''' | |||
|'''[[HLA-B27]]''' | |||
|- | |||
|'''[[Psoriatic arthritis]]''' | |||
| + | |||
| + | |||
| ++ | |||
| + | |||
| + | |||
| + | |||
| + | |||
| +++ ([[Distal interphalangeal joints|DIP]]/[[Proximal interphalangeal joints|PIP]]) | |||
| +++ | |||
| ++ (Unilateral) | |||
| ++ | |||
| - | |||
| ++ (Widening) | |||
| ++ | |||
| +++ (Fluffy) | |||
| ++ | |||
| + | |||
| - | |||
|30-75% | |||
|- | |||
|'''[[Rheumatoid arthritis]]''' | |||
| - | |||
| ++ | |||
| + | |||
| - | |||
| - | |||
| - | |||
| - | |||
| +++ | |||
([[MCP joints|MCP]]/[[wrist]]) | |||
| +++ | |||
| + (Unilateral) | |||
| ++([[Cervical spine|Cervical]]) | |||
| +++ | |||
| +++ (Narrowing) | |||
| + | |||
| + (Linear) | |||
| +++ | |||
| +++ | |||
| +++ | |||
|6-8% | |||
|- | |||
|'''[[Ankylosing spondylitis]]''' | |||
| - | |||
| +++ | |||
| - | |||
| + | |||
| - | |||
| - | |||
| - | |||
| + | |||
| + | |||
| +++ (Bilateral) | |||
| +++ | |||
| +++ | |||
| ++ (Narrowing) | |||
| +++ | |||
| +++ (Fluffy) | |||
| + | |||
| +++ | |||
| - | |||
|90% | |||
|- | |||
|'''[[Reactive arthritis]] ([[Reiter's syndrome]])''' | |||
| - | |||
| +++ | |||
| - | |||
| + | |||
| + | |||
| - | |||
| - | |||
| ++ | |||
| +++ | |||
| ++ (Unilateral) | |||
| + | |||
| + | |||
| + (Narrowing) | |||
| - | |||
| +++ (Fluffy) | |||
| ++ | |||
| ++ | |||
| - | |||
|75% | |||
|} | |||
Key:+ : Infrequently present, ++ : Frequently present, +++ : Always present, - : Absent | |||
==References== | |||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} [[Category:Arthritis]] [[Category:Autoimmune diseases]] | ||
[[Category:Arthritis]] | |||
[[Category:Autoimmune diseases]] |
Revision as of 18:17, 10 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ankylosing spondylitis needs to be differentiated from certain conditions such as a strain of the psoriatic arthritis,rheumatoid arthritis and reactive arthritis.
Differentiating Ankylosing spondylitis from other Diseases
- Ankylosing spondylitis must be differentiated from other diseases causing oligo/polyarthritis or arthritis of the axial skeleton, including: {| class="wikitable" ! align="center" style="background:#4479BA; color: #FFFFFF;" + |Arthritis Type ! colspan="7" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Clinical Features ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Body Distribution ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Key Signs ! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" ! + |Laboratory Abnormalities |- | |History of Psoriasis |Symmetric joint involvement |Asymmetric joint involvement |Enthesopathy |Dactylitis |Nail Dystrophy |Human immunodeficiency virus association |Upper extremity-hands |Lower extremity |Sacroiliac joints |Spine |Osteopenia |Joint Space |Ankylosis |Periostitis |Soft tissue swelling |ESR |Rheumatoid factor (RF) |HLA-B27 |- |Psoriatic arthritis | + | + | ++ | + | + | + | + | +++ (DIP/PIP) | +++ | ++ (Unilateral) | ++ | - | ++ (Widening) | ++ | +++ (Fluffy) | ++ | + | - |30-75% |- |Rheumatoid arthritis | - | ++ | + | - | - | - | - | +++ (MCP/wrist) | +++ | + (Unilateral) | ++(Cervical) | +++ | +++ (Narrowing) | + | + (Linear) | +++ | +++ | +++ |6-8% |- |Ankylosing spondylitis | - | +++ | - | + | - | - | - | + | + | +++ (Bilateral) | +++ | +++ | ++ (Narrowing) | +++ | +++ (Fluffy) | + | +++ | - |90% |- |Reactive arthritis (Reiter's syndrome) | - | +++ | - | + | + | - | - | ++ | +++ | ++ (Unilateral) | + | + | + (Narrowing) | - | +++ (Fluffy) | ++ | ++ | - |75% |} Key:+ : Infrequently present, ++ : Frequently present, +++ : Always present, - : Absent ==References==