Buerger's disease natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of [disease name] include amputation, gangrene and loss of circulation beyond the affected hand or foot. Smoking cessation leads to an 8-fold decrease in the risk for amputation. Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. Buerger's is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels. | If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of [disease name] include amputation, gangrene and loss of circulation beyond the affected hand or foot. Smoking cessation leads to an 8-fold decrease in the risk for amputation. Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. Buerger's is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels. | ||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
===Natural History=== | ===Natural History=== | ||
*The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as pallor and ischemia of the extremities. | *The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as pallor and ischemia of the extremities.<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | ||
*If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. | *If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. | ||
===Complications=== | ===Complications=== | ||
*Common complications of Buerger disease include: | *Common complications of Buerger disease include:<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | ||
**Amputation | **Amputation | ||
**Gangrene | **Gangrene | ||
| Line 20: | Line 19: | ||
===Prognosis=== | ===Prognosis=== | ||
*Smoking cessation leads to an 8-fold decrease in the risk for amputation. | *Smoking cessation leads to an 8-fold decrease in the risk for amputation.<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | ||
*Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. | *Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. | ||
*Buerger's disease is rarely immediately fatal, but rather a life shortening disease. | *Buerger's disease is rarely immediately fatal, but rather a life shortening disease. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of [disease name] include amputation, gangrene and loss of circulation beyond the affected hand or foot. Smoking cessation leads to an 8-fold decrease in the risk for amputation. Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. Buerger's is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as pallor and ischemia of the extremities.[1][2]
- If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease.
Complications
- Common complications of Buerger disease include:[1][2]
- Amputation
- Gangrene
- Loss of circulation beyond the affected hand or foot
Prognosis
- Smoking cessation leads to an 8-fold decrease in the risk for amputation.[1][2]
- Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency.
- Buerger's disease is rarely immediately fatal, but rather a life shortening disease.
- Prognosis of Buerger's disease varies from person to person, depending on:
- The patient's life-style
- The severity of the damaged vessels
References
- ↑ 1.0 1.1 1.2 Ohta T, Ishioashi H, Hosaka M, Sugimoto I (January 2004). "Clinical and social consequences of Buerger disease". J. Vasc. Surg. 39 (1): 176–80. doi:10.1016/j.jvs.2003.08.006. PMID 14718836.
- ↑ 2.0 2.1 2.2 Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV (December 2004). "Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease)". J. Am. Coll. Cardiol. 44 (12): 2410–1. doi:10.1016/j.jacc.2004.09.029. PMID 15607407.