Vitamin B12 deficiency historical perspective: Difference between revisions

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{{Vitamin B12 deficiency}}
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=== Common Causes ===
Vitamin B 12 deficiency  may be caused by:


==Overview==
=== Decrease intake ===
* Strict vegan diet more than 3 years .
* Breast fed infants of pure vegan may also develop deficiency .
* Malnutrition most likely happen in elderly patients.


==Historical Perspective==
=== Malabsorption ===
 
* Decrease intrinsic factor  due autoimmune destruction of parietal cell
* Vitamin B12 deficiency was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
* Decrease Gastric acid production  due to proton pump inhibitor and histamine 2 receptor antagonists
* Gastric by pass surgery because intrinsic factor is produce by parietal cell of stomach 
* Tapeworm  (Diphyllobothrium latum )  ingested from contaminated fish , tapeworm saps nutrients
* Crohn's disease


* The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
=== Increased requirement ===
* In [year], [scientist] was the first to discover the association be
* pregnancy


==References==
==References==

Revision as of 02:29, 29 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Common Causes

Vitamin B 12 deficiency may be caused by:

Decrease intake 

  • Strict vegan diet more than 3 years .
  • Breast fed infants of pure vegan may also develop deficiency .
  • Malnutrition most likely happen in elderly patients.

Malabsorption

  • Decrease intrinsic factor  due autoimmune destruction of parietal cell
  • Decrease Gastric acid production due to proton pump inhibitor and histamine 2 receptor antagonists
  • Gastric by pass surgery because intrinsic factor is produce by parietal cell of stomach 
  • Tapeworm (Diphyllobothrium latum ) ingested from contaminated fish , tapeworm saps nutrients
  • Crohn's disease

Increased requirement

  • pregnancy

References

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