Hyponatremia differential diagnosis

Hyponatremia Microchapters
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Differentiating Hyponatremia from other Diseases
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2] Iqra Qamar M.D.[3]

Overview

Hyponatremia must be differentiated from other diseases that cause

Differentiating Hyponatremia from other Diseases

Classification by volume status	Disease	Clinical manifestations												Paraclinical Findings								Comments
Hypervolemic		Symptoms and Signs												Lab Findings							Imaging
		Muscle weakness/ Cramps	Thirst	Vomiting/ Diarrhea	Confusion/ Dizziness	Seizures	JVP	Edema	Crackles	Ascites	Tachycardia	Hypotension	Oliguria	CBC	Urine Analysis			Serum Osmolality	ADH levels	Other
															Urine Na	Urine Osm	FeNa
	Renal failure
	Congestive heart failure
	Cirrhosis
Euvolemic	SIADH
	Hypothyroidism
	Adrenal insufficiency
	Psychogenic polydipsia
	Pregnancy
	Anorexia (Chronic malnutrition)
Hypovolemic	Diuretic induced hyponatremia
	Non oliguric ATN
	Diseases causing 3rd spacing (Pancreatitis, SBO)
	Gastroenteritis
	Sweating