Polyarthritis with joint swelling, fever, and weight loss: Difference between revisions

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{{CMG}}; {{AE}}{{EG}}
{{CMG}}; {{AE}}{{EG}}
 
<small>
{| align="center" style="border: 0px; font-size: 90%; margin: 3px;"
{| align="center" style="border: 0px; font-size: 90%; margin: 3px;"
! colspan="3" rowspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Diseases
! colspan="3" rowspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Diseases
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! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
|-
|-
! rowspan="21" style="background: #DCDCDC; padding: 5px; text-align: center;" |Polyarthritis
! rowspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Polyarthritis
! rowspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Infectious arthritis]]
! rowspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Infectious arthritis]]
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Lyme disease]]<ref name="pmid25999227">{{cite journal| author=Lantos PM| title=Chronic Lyme disease. | journal=Infect Dis Clin North Am | year= 2015 | volume= 29 | issue= 2 | pages= 325-40 | pmid=25999227 | doi=10.1016/j.idc.2015.02.006 | pmc=4477530 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25999227  }}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Lyme disease]]<ref name="pmid25999227">{{cite journal| author=Lantos PM| title=Chronic Lyme disease. | journal=Infect Dis Clin North Am | year= 2015 | volume= 29 | issue= 2 | pages= 325-40 | pmid=25999227 | doi=10.1016/j.idc.2015.02.006 | pmc=4477530 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25999227  }}</ref>
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! style="background: #F5F5F5; padding: 5px;" |[[Vertebral osteomyelitis]]
! style="background: #F5F5F5; padding: 5px;" |[[Vertebral osteomyelitis]]
|-
|-
! rowspan="3" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Reactive arthritis|Postinfectious (reactive) arthritis]]'''
! style="background: #DCDCDC; padding: 5px; text-align: center;" |Polyarticular pain
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Rheumatic fever]]<ref name="pmid23703332">{{cite journal| author=Kumar RK, Tandon R| title=Rheumatic fever & rheumatic heart disease: the last 50 years. | journal=Indian J Med Res | year= 2013 | volume= 137 | issue= 4 | pages= 643-58 | pmid=23703332 | doi= | pmc=3724245 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23703332  }}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |Viral arthritis
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |[[Erythema marginatum|Erythema marginatum rheumaticum]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Sterile inflammatory reaction with cells<20,000/μL
! style="background: #F5F5F5; padding: 5px;" |[[Anti-streptolysin O titer|Streptococcal antibody titer]]
! style="background: #F5F5F5; padding: 5px;" |[[Cardiomegaly]]
! style="background: #F5F5F5; padding: 5px;" |[[Valvular Diseases|Valvular]] or [[pericardial calcification]]
! style="background: #F5F5F5; padding: 5px;" |[[Echocardiography|Echocardiographic]] changes in heart valves
! style="background: #F5F5F5; padding: 5px;" |[[Edema]], [[Fibrinoid necrosis]], [[Mononuclear cell|Mononuclear cell infiltrate]]
! style="background: #F5F5F5; padding: 5px;" |[[Echocardiography]]
! style="background: #F5F5F5; padding: 5px;" |Chorea, Carditis 
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Reactive arthritis]]<ref name="pmid15084505">{{cite journal| author=Colmegna I, Cuchacovich R, Espinoza LR| title=HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations. | journal=Clin Microbiol Rev | year= 2004 | volume= 17 | issue= 2 | pages= 348-69 | pmid=15084505 | doi= | pmc=387405 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15084505  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Genital]] [[ulceration]]
! style="background: #F5F5F5; padding: 5px;" |[[Normocytic normochromic anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" | High [[WBC]] count (10,000-40,000/µL)
! style="background: #F5F5F5; padding: 5px;" | [[HLA-B27|HLA-B27 test]] 
! style="background: #F5F5F5; padding: 5px;" |[[Periosteal reaction]] and proliferation of [[Enthesitis|tendon insertion site]]
! style="background: #F5F5F5; padding: 5px;" |[[Sacroiliitis]]
! style="background: #F5F5F5; padding: 5px;" |[[Enthesitis]] in [[ultrasonography]]
! style="background: #F5F5F5; padding: 5px;" |[[Keratoderma blennorrhagica|Keratoderma blennorrhagicum]],  [[Balanitis circinata]] 
! style="background: #F5F5F5; padding: 5px;" | [[Spondyloarthritis]] and unequivocal demonstration of preceding infection
! style="background: #F5F5F5; padding: 5px;" |[[Conjunctivitis]], [[Uveitis]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Enteric Bacilli|Enteric infection]]<ref name="Hill Gaston2003">{{cite journal|last1=Hill Gaston|first1=J|title=Arthritis associated with enteric infection|journal=Best Practice & Research Clinical Rheumatology|volume=17|issue=2|year=2003|pages=219–239|issn=15216942|doi=10.1016/S1521-6942(02)00104-3}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Keratoderma]] and psoriaform lesions, [[Erythema nodosum]]
! style="background: #F5F5F5; padding: 5px;" |[[Neutrophilia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |[[PCR]] of causative [[organism]]
! style="background: #F5F5F5; padding: 5px;" |[[Stool examination|Stool exam]] and [[Stool culture|culture]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Neutrophilic myelocyte|Neutrophilic]] infiltration in [[synovial]] tissues
! style="background: #F5F5F5; padding: 5px;" |[[PCR]] of causative [[organism]] in [[synovial fluid]]
! style="background: #F5F5F5; padding: 5px;" |[[Diarrhea]], [[Enthesopathy]]
|-
! rowspan="3" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Other [[Seronegative spondyloarthritis|seronegative spondyloarthritides]]'''
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Ankylosing spondylitis]]<ref name="pmid16974012">{{cite journal| author=McVeigh CM, Cairns AP| title=Diagnosis and management of ankylosing spondylitis. | journal=BMJ | year= 2006 | volume= 333 | issue= 7568 | pages= 581-5 | pmid=16974012 | doi=10.1136/bmj.38954.689583.DE | pmc=1570004 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16974012  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Dactylitis]] (sausage digit)
! style="background: #F5F5F5; padding: 5px;" |[[Normocytic normochromic anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" | High [[WBC]] count ([[lymphocyte]] predominance)
! style="background: #F5F5F5; padding: 5px;" |↑[[Alkaline phosphatase|Alkaline phosphatase (ALP)]]
! style="background: #F5F5F5; padding: 5px;" |Bony [[Erosion (dental)|erosions]] and [[sclerosis]] of the [[joints]] 
! style="background: #F5F5F5; padding: 5px;" |Early [[sacroiliitis]], [[Erosion (dental)|erosions]], and [[enthesitis]]
! style="background: #F5F5F5; padding: 5px;" |Possible [[cauda equina syndrome]] secondary to [[spinal stenosis]] in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Chronic [[inflammation]] with [[CD4+|CD4<sup>+</sup>]] and [[CD8+ T cells|CD8<sup>+</sup> T lymphocytes]] and [[macrophages]]
! style="background: #F5F5F5; padding: 5px;" |[[X-rays|Plain x-rays]]
! style="background: #F5F5F5; padding: 5px;" |Peripheral [[enthesitis]], [[Uveitis]] 
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Psoriatic arthritis]]<ref name="pmid23493653">{{cite journal| author=Sankowski AJ, Lebkowska UM, Cwikła J, Walecka I, Walecki J| title=Psoriatic arthritis. | journal=Pol J Radiol | year= 2013 | volume= 78 | issue= 1 | pages= 7-17 | pmid=23493653 | doi=10.12659/PJR.883763 | pmc=3596149 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23493653  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |Scaly [[Erythematous rash|erythematous plaques]],
 
[[Guttate psoriasis|Guttate lesions]], Lakes of [[pus]],
 
[[Erythroderma]]
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |High [[WBC]] count (5000-15,000/µL) with >50% of [[PMN|PMN leukocytes]]
! style="background: #F5F5F5; padding: 5px;" |↑[[RF]], [[ANA]], [[IgA]]
! style="background: #F5F5F5; padding: 5px;" |[[Joint]]-space narrowing, [[Periostitis|Fluffy periostitis]]
! style="background: #F5F5F5; padding: 5px;" |Pencil-in-cup deformity, Early signs of [[synovitis]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovitis|Sacroiliitic synovitis]], [[Enthesitis]] in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Lack of intrasynovial [[Immunoglobulin A|Ig]] and [[RF]], Greater propensity for [[Ankylosis|fibrous ankylosis]], [[Osseous|osseous resorption]], and [[Heterotopic ossification|heterotopic bone formation]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings
! style="background: #F5F5F5; padding: 5px;" |[[Onycholysis]], [[Splinter hemorrhage|Splinter hemorrhages]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Inflammatory bowel disease]]<ref name="pmid22933865">{{cite journal| author=Orchard TR| title=Management of arthritis in patients with inflammatory bowel disease. | journal=Gastroenterol Hepatol (N Y) | year= 2012 | volume= 8 | issue= 5 | pages= 327-9 | pmid=22933865 | doi= | pmc=3424429 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22933865  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |[[Pyoderma gangrenosum]] ([[ulcerative colitis]]),  [[Erythema nodosum]] ([[Crohn disease]])
! style="background: #F5F5F5; padding: 5px;" |[[Iron deficiency anemia]], [[Leukocytosis]], [[Thrombocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Mild to moderate [[Inflammatory|inflammatory fluid]], [[PMN]] predominance
! style="background: #F5F5F5; padding: 5px;" |↑[[RF]], [[Endomysium|Antiendomysial Ab]],  [[Anti-transglutaminase antibodies|Antitransglutaminase Ab]]
! style="background: #F5F5F5; padding: 5px;" |Bilateral [[sacroiliitis]], Syndesmophytes and apophyseal joint involvement in [[spine]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Early detection of [[Spinal stenosis|spinal]] and [[Sacroiliac joint|sacroiliac lesions]] in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Clinical findings and history
! style="background: #F5F5F5; padding: 5px;" |[[Anterior uveitis|Acute anterior uveitis]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Rheumatoid arthritis]]'''<ref name="pmid24024009">{{cite journal| author=Heidari B| title=Rheumatoid Arthritis: Early diagnosis and treatment outcomes. | journal=Caspian J Intern Med | year= 2011 | volume= 2 | issue= 1 | pages= 161-70 | pmid=24024009 | doi= | pmc=3766928 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24024009  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Rheumatoid nodules]]
! style="background: #F5F5F5; padding: 5px;" |[[Anemia]], [[Thrombocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |[[WBC]] count >2000/µL (generally 5000-50,000/µL), with [[neutrophil]] predominance (60-80%)
! style="background: #F5F5F5; padding: 5px;" |[[Anti-citrullinated protein antibody|Anti-CCP Ab]], [[Hyperuricemia]]
! style="background: #F5F5F5; padding: 5px;" |[[Joint]]-space narrowing
! style="background: #F5F5F5; padding: 5px;" |[[Fractures|Microfractures]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovitis]] in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Influx of [[inflammatory cells]] into the [[synovial membrane]], with  [[angiogenesis]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings coupled [[Anti-citrullinated protein antibody|anti-CCP antibody]]
! style="background: #F5F5F5; padding: 5px;" |[[Rheumatoid nodules]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Crystal arthritis|Crystal-induced arthritis]]'''<ref name="pmid62879632">{{cite journal |vauthors=Reginato A, Paul H, Schumacher HR |title=Crystal-induced arthritis |journal=Arch Phys Med Rehabil |volume=63 |issue=9 |pages=401–8 |date=September 1982 |pmid=6287963 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |Joint [[erythema]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Needle shaped [[urate]] crystals, [[WBC]] count > 2000/µL
! style="background: #F5F5F5; padding: 5px;" |Urinary [[uric acid]] (>1100 mg in 24h)
! style="background: #F5F5F5; padding: 5px;" |Punched-out erosions or [[lytic]] areas with overhanging edges 
! style="background: #F5F5F5; padding: 5px;" |Complementary for recognizing [[Erosion (dental)|erosions]]
! style="background: #F5F5F5; padding: 5px;" |[[Tophus|Tophi]] or [[edema]] in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Large pale pink acellular areas ([[Uric acid|urate crystals]]), surrounded by [[histiocytes]] and [[multinucleated giant cells]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovial fluid]] assay
! style="background: #F5F5F5; padding: 5px;" |[[Conjunctival|Conjunctival nodules]]
|-
! rowspan="7" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Systemic [[Rheumatic disease|rheumatic illnesses]]'''
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Systemic lupus erythematosus]]<ref name="pmid16722594">{{cite journal| author=Manson JJ, Rahman A| title=Systemic lupus erythematosus. | journal=Orphanet J Rare Dis | year= 2006 | volume= 1 | issue=  | pages= 6 | pmid=16722594 | doi=10.1186/1750-1172-1-6 | pmc=1459118 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16722594  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |[[Malar rash]], [[Photosensitivity]], [[Discoid lupus]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukopenia]], [[Lymphopenia]], [[Anemia]], [[Thrombocytopenia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell count from < 25% [[PMNs]] (non-[[inflammatory]] effusions) to > 50% [[PMNs]] ([[inflammatory]] effusions)
! style="background: #F5F5F5; padding: 5px;" |[[Creatine kinase]], [[Liver function tests|LFT]], [[ANA]], [[Anti-dsDNA antibody|Anti-dsDNA]], [[Anti-SM antibody|Anti-Sm]], [[Lupus anticoagulant]]
! style="background: #F5F5F5; padding: 5px;" |Periarticular [[osteopenia]] and [[Soft tissue injury|soft-tissue swelling]] without [[Erosion (dental)|erosions]]
! style="background: #F5F5F5; padding: 5px;" |[[Interstitial lung disease]], [[Pneumonitis]], [[Pulmonary emboli]], [[Alveolar Cyst Disease|Alveolar hemorrhage]]
! style="background: #F5F5F5; padding: 5px;" |[[Pericardial effusion]], [[Pulmonary hypertension]], [[Libman-Sacks endocarditis|Verrucous Libman-Sacks endocarditis]] in [[echocardiography]]
! style="background: #F5F5F5; padding: 5px;" |[[Inflammatory]] infiltrates at the dermoepidermal junction and vacuolar change in the basal [[Columnar epithelium|columnar cells]]
! style="background: #F5F5F5; padding: 5px;" |[[Anti-dsDNA antibody|Anti-dsDNA]]
! style="background: #F5F5F5; padding: 5px;" |[[Rheumatoid arthritis]], [[Serositis]], [[Oral ulcers]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Systemic vasculitis]]<ref name="pmid27964796">{{cite journal |vauthors=Watts RA, Scott DG |title=Vasculitis and inflammatory arthritis |journal=Best Pract Res Clin Rheumatol |volume=30 |issue=5 |pages=916–931 |date=October 2016 |pmid=27964796 |doi=10.1016/j.berh.2016.10.008 |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Petechia]], [[Purpura]]
! style="background: #F5F5F5; padding: 5px;" |[[Anemia]], [[Thrombocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[P-ANCA]], [[C-ANCA]][[ANA|, ANA]]
! style="background: #F5F5F5; padding: 5px;" |[[Soft tissue pathology|Soft tissue swelling]] with mild [[Erosion (dental)|erosions]]
! style="background: #F5F5F5; padding: 5px;" |Focal regions of [[infarction]] or [[hemorrhage]]
! style="background: #F5F5F5; padding: 5px;" |Multiple [[Aneurysm|microaneurysms]],[[Hemorrhage]] due to focal [[rupture]], [[Occlusion]] in [[angiography]]
! style="background: #F5F5F5; padding: 5px;" |Acute destruction of the [[Tunica media|media]] by [[neutrophils]], with loss of [[elastic fibers]]
! style="background: #F5F5F5; padding: 5px;" |[[Angiography]]
! style="background: #F5F5F5; padding: 5px;" |[[Peripheral neuropathy]], [[Livedo reticularis]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Systemic sclerosis]]<ref name="AvouacClements2012">{{cite journal|last1=Avouac|first1=J.|last2=Clements|first2=P. J.|last3=Khanna|first3=D.|last4=Furst|first4=D. E.|last5=Allanore|first5=Y.|title=Articular involvement in systemic sclerosis|journal=Rheumatology|volume=51|issue=8|year=2012|pages=1347–1356|issn=1462-0324|doi=10.1093/rheumatology/kes041}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |3 phases of (1) [[Edema|Edematous]], (2) [[Induration|Indurative]], and (3) [[Atrophic]]
! style="background: #F5F5F5; padding: 5px;" |[[Thrombocytopenia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" |[[Hypergammaglobulinemia]],
 
[[Creatine phosphokinase]]
! style="background: #F5F5F5; padding: 5px;" |Juxta-[[articular]] [[osteoporosis]], Joint space narrowing, Frank [[Erosion (dental)|erosions]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovial inflammation]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovial]] [[vascularity]] in [[doppler ultrasonography]]
! style="background: #F5F5F5; padding: 5px;" |[[Epidermal]] [[skin appendages]] [[atrophy]], Broad and hyalinized [[collagen]] fibers in the [[reticular dermis]]
! style="background: #F5F5F5; padding: 5px;" |[[Histopathology]]
! style="background: #F5F5F5; padding: 5px;" |[[Raynaud phenomenon]], [[Tendon]] [[Friction rub|friction rubs]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Polymyositis]]/[[dermatomyositis]]<ref name="pmid12895397">{{cite journal |vauthors=Briemberg HR, Amato AA |title=Dermatomyositis and Polymyositis |journal=Curr Treat Options Neurol |volume=5 |issue=5 |pages=349–356 |date=September 2003 |pmid=12895397 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |[[Heliotropism|Heliotrope rash]], [[Dermatomyositis|Gottron papules]], [[Poikiloderma of civatte|Poikiloderma]]
! style="background: #F5F5F5; padding: 5px;" |[[Normocytic normochromic anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Predominantly [[mononuclear cells]] and large macrophage-like cells
! style="background: #F5F5F5; padding: 5px;" |Anti–Mi-2 antibodies, Anti–Jo-1 antibodies, [[Creatine kinase]], [[ANA]]
! style="background: #F5F5F5; padding: 5px;" |Marginal [[Erosion (dental)|erosions]] and periarticular [[calcification]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Vacuolar changes of the [[columnar epithelium]] and [[lymphocytic]] [[Infiltration (medical)|infiltrates]]
! style="background: #F5F5F5; padding: 5px;" |[[Muscle biopsy]]
! style="background: #F5F5F5; padding: 5px;" |[[Dysphagia]] 
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Still's disease]]<ref name="pmid25613167">{{cite journal |vauthors=Kadavath S, Efthimiou P |title=Adult-onset Still's disease-pathogenesis, clinical manifestations, and new treatment options |journal=Ann. Med. |volume=47 |issue=1 |pages=6–14 |date=February 2015 |pmid=25613167 |doi=10.3109/07853890.2014.971052 |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |Mild [[papules]] and [[nodules]]
! style="background: #F5F5F5; padding: 5px;" |[[Anemia]], [[Thrombocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |High [[WBC]] count (5000-15,000/µL) with >50% of [[PMN|PMN leukocytes]]
! style="background: #F5F5F5; padding: 5px;" |[[ANA]], [[RF]]
! style="background: #F5F5F5; padding: 5px;" |Soft tissue swelling,
 
[[Osteopenia]],
 
Joint-space narrowing
! style="background: #F5F5F5; padding: 5px;" |[[Synovial inflammation]]
! style="background: #F5F5F5; padding: 5px;" |Inflamed [[synovium]] in [[ultrasonography]]
! style="background: #F5F5F5; padding: 5px;" |[[Inflammatory]] [[Infiltration (medical)|infiltration]] in [[synovium]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings and [[synovial fluid]] analysis
! style="background: #F5F5F5; padding: 5px;" |[[Ocular|Ocular involvement]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Behçet's disease|Behçet's syndrome]]<ref name="pmid20121672">{{cite journal |vauthors=Sugawara S, Ehara S, Hitachi S, Sugimoto H |title=Hand and wrist arthritis of Behçet disease: imaging features |journal=Acta Radiol |volume=51 |issue=2 |pages=183–6 |date=March 2010 |pmid=20121672 |doi=10.3109/02841850903401349 |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Erythema nodosum]]
! style="background: #F5F5F5; padding: 5px;" |[[Normocytic normochromic anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" |Serum [[complement]] levels, [[Human leukocyte antigen]] (HLA)-B51
! style="background: #F5F5F5; padding: 5px;" |Soft tissue swelling
! style="background: #F5F5F5; padding: 5px;" |Non-erosive [[synovitis]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Dermal vessels infiltration with lymphocytes and plasma cells, [[Immune]] deposits of [[Immunoglobulin M|immunoglobulin M (IgM)]] and [[C3]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings
! style="background: #F5F5F5; padding: 5px;" |[[Oral ulcer]], [[Mucosal]] erosion
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Relapsing polychondritis]]<ref name="pmid27708954">{{cite journal| author=Emmungil H, Aydın SZ| title=Relapsing polychondritis. | journal=Eur J Rheumatol | year= 2015 | volume= 2 | issue= 4 | pages= 155-159 | pmid=27708954 | doi=10.5152/eurjrheum.2015.0036 | pmc=5047229 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27708954  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]], [[Anemia]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" |[[Cryoglobulins]], [[ANA]], [[C-ANCA]]
! style="background: #F5F5F5; padding: 5px;" |[[Tracheal stenosis]] in [[CXR]]
! style="background: #F5F5F5; padding: 5px;" |[[Calcification]] of [[Cartilaginous|cartilaginous structures]]
! style="background: #F5F5F5; padding: 5px;" |[[Aortic root|Aortic root dilatation]] and degree of [[aortic regurgitation]] in [[echocardiography]]
! style="background: #F5F5F5; padding: 5px;" |Chondrolysis, [[Chondritis]], Perichondritis
! style="background: #F5F5F5; padding: 5px;" |Clinical findings coupled with imaging
! style="background: #F5F5F5; padding: 5px;" |[[Ear pain]] and redness, [[Polyarthritis]]
|-
! rowspan="4" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Other systemic illnesses'''
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Sarcoidosis]]<ref name="pmid18032765">{{cite journal |vauthors=Iannuzzi MC, Rybicki BA, Teirstein AS |title=Sarcoidosis |journal=N. Engl. J. Med. |volume=357 |issue=21 |pages=2153–65 |date=November 2007 |pmid=18032765 |doi=10.1056/NEJMra071714 |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Mild [[papules]] and [[nodules]]
! style="background: #F5F5F5; padding: 5px;" |Mild [[anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" | [[IL-2]] and [[Interferon gamma|IFN-γ]], ↑[[Angiotensin-converting enzyme|ACE]], ↑[[Vitamin D|1, 25-dihydroxyvitamin D]]
! style="background: #F5F5F5; padding: 5px;" |Bilateral [[Adenopathy|hilar adenopathy]]
! style="background: #F5F5F5; padding: 5px;" |Active [[alveolitis]] or [[fibrosis]]
! style="background: #F5F5F5; padding: 5px;" |[[Hepatosplenomegaly]] in [[ultrasonography]]
! style="background: #F5F5F5; padding: 5px;" |[[Granuloma|Noncaseating granulomas (NCGs)]]
! style="background: #F5F5F5; padding: 5px;" |[[Histopathology|Histological confirmation]]
! style="background: #F5F5F5; padding: 5px;" |[[Heart block]], [[Ocular disease|Ocular lesion]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Palindromic rheumatism]]<ref name="pmid21206416">{{cite journal |vauthors=Iyer VR, Cohen GL |title=Palindromic rheumatism |journal=South. Med. J. |volume=104 |issue=2 |pages=147–9 |date=February 2011 |pmid=21206416 |doi=10.1097/SMJ.0b013e318200c4cc |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Rheumatoid nodules]]
! style="background: #F5F5F5; padding: 5px;" |[[Anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |High [[WBC]] count (5000-15,000/µL) with >50% of [[PMN|PMN leukocytes]]
! style="background: #F5F5F5; padding: 5px;" |[[RF]], [[Anti-citrullinated protein antibody|Anti-CCP antibody]], ↑[[Creatinine|Cr]] or [[Blood urea nitrogen|BUN]],
 
↑[[ALT]] or [[AST]], [[ANA]]
! style="background: #F5F5F5; padding: 5px;" |[[Joint (anatomy)|Effusions in joints]]
! style="background: #F5F5F5; padding: 5px;" |[[Fractures|Microfractures]]
! style="background: #F5F5F5; padding: 5px;" |Basilar invagination with [[cranial]] migration of an eroded [[Odontoid process|odontoid]] peg in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Influx of [[inflammatory cells]] into the [[synovial membrane]], with[[angiogenesis]], proliferation of chronic [[inflammatory cells]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings coupled [[Anti-citrullinated protein antibody|anti-CCP antibody]]
! style="background: #F5F5F5; padding: 5px;" |[[Rheumatoid nodules]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Familial mediterranean fever|Familial Mediterranean fever]]<ref name="pmid25610168">{{cite journal| author=Yildirim K, Uzkeser H, Uyanik A, Karatay S, Kiziltunc A| title=Trace element levels in patients with familial mediterranean Fever. | journal=Eurasian J Med | year= 2011 | volume= 43 | issue= 2 | pages= 79-82 | pmid=25610168 | doi=10.5152/eajm.2011.18 | pmc=4261345 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25610168  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |A well-demarcated, [[erythematous]], warm [[rash]], particularly below the [[knee]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell counts as high as 100,000/µL
! style="background: #F5F5F5; padding: 5px;" |[[CRP]], [[Amyloid bodies|Amyloid A protein]], [[Fibrinogen]]
! style="background: #F5F5F5; padding: 5px;" |[[Synovial inflammation|Synovial effusions]]
! style="background: #F5F5F5; padding: 5px;" |[[Pleural effusions]]
! style="background: #F5F5F5; padding: 5px;" |Air-fluid levels in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |Massive [[amyloid]] infiltration of the [[blood vessels]] and [[endothelial]] side of the [[glomerular basement membrane]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings
! style="background: #F5F5F5; padding: 5px;" |[[Abdominal pain]], [[Myalgia|Severe myalgia]], [[Scrotal swelling|Scrotal attacks]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hyperlipoproteinemia|Hyperlipoproteinemias]]<ref name="SoubrierDubost2009">{{cite journal|last1=Soubrier|first1=Martin|last2=Dubost|first2=Jean Jacques|last3=Thiéblot|first3=Philippe|last4=Ristori|first4=Jean Michel|title=Oligo-arthritis and type IV hyperlipoproteinemia|journal=Joint Bone Spine|volume=76|issue=1|year=2009|pages=95–97|issn=1297319X|doi=10.1016/j.jbspin.2008.03.009}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Xanthelasma]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |[[Xanthochromic]] fluid with [[mononuclear cells]] predominance
! style="background: #F5F5F5; padding: 5px;" |[[CRP]], [[Hyperlipidemia (patient information)|Hyperlipidemia]]
! style="background: #F5F5F5; padding: 5px;" |Joint space narrowing
! style="background: #F5F5F5; padding: 5px;" |[[Achilles tendon]] [[enthesitis]]
! style="background: #F5F5F5; padding: 5px;" |[[Retrocalcaneal bursitis]] and ill-defined [[edema]] in posterosuperior corner of the [[calcaneus]]
! style="background: #F5F5F5; padding: 5px;" |[[Inflammatory]] infiltration
! style="background: #F5F5F5; padding: 5px;" |Laboratory findings
! style="background: #F5F5F5; padding: 5px;" |[[Atherosclerosis]]
|-
! rowspan="9" style="background: #DCDCDC; padding: 5px; text-align: center;" |Polyarticular pain
! rowspan="3" style="background: #DCDCDC; padding: 5px; text-align: center;" |Viral arthritis
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Hepatitis B]] and [[Hepatitis C|C]]'''<ref name="GanemPrince2004">{{cite journal|last1=Ganem|first1=Don|last2=Prince|first2=Alfred M.|title=Hepatitis B Virus Infection — Natural History and Clinical Consequences|journal=New England Journal of Medicine|volume=350|issue=11|year=2004|pages=1118–1129|issn=0028-4793|doi=10.1056/NEJMra031087}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Urticaria|Urticarial]] and [[maculopapular]] [[Eruption|eruptions]] 
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell counts < 100,000/µL
! style="background: #F5F5F5; padding: 5px;" |[[LFTs|LFT]], [[HBsAg]]
! style="background: #F5F5F5; padding: 5px;" |Joint space narrowing
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Deposition of [[immune complexes]], [[Cryoprecipitate|Cryoprecipitates]] containing [[HBsAg]] and [[Complement|complements]]
! style="background: #F5F5F5; padding: 5px;" |[[HBsAg]]
! style="background: #F5F5F5; padding: 5px;" |[[Liver failure]], [[Jaundice|Icterus]]
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Rubella]]'''<ref name="pmid849368">{{cite journal |vauthors=Spruance SL, Metcalf R, Smith CB, Griffiths MM, Ward JR |title=Chronic arthropathy associated with rubella vaccination |journal=Arthritis Rheum. |volume=20 |issue=2 |pages=741–7 |date=March 1977 |pmid=849368 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Acute [[maculopapular rash]]
! style="background: #F5F5F5; padding: 5px;" |[[Leukocytosis]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |[[Rubella virus|Rubella virus  antigen]]
! style="background: #F5F5F5; padding: 5px;" |[[LFTs|LFT]], [[CRP]]
! style="background: #F5F5F5; padding: 5px;" |Joint space narrowing
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |proliferation of the [[Synovial membrane|synovial lining cells]], without [[Inflammatory cells|inflammatory]]
 
[[Inflammatory cells|cells]]
! style="background: #F5F5F5; padding: 5px;" |[[Serological testing|Serological evidence]]
! style="background: #F5F5F5; padding: 5px;" |[[Headache]], [[Malaise]]
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Parvovirus]]'''<ref name="pmid10910181">{{cite journal |vauthors=Moore TL |title=Parvovirus-associated arthritis |journal=Curr Opin Rheumatol |volume=12 |issue=4 |pages=289–94 |date=July 2000 |pmid=10910181 |doi= |url=}}</ref>
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Parvovirus]]'''<ref name="pmid10910181">{{cite journal |vauthors=Moore TL |title=Parvovirus-associated arthritis |journal=Curr Opin Rheumatol |volume=12 |issue=4 |pages=289–94 |date=July 2000 |pmid=10910181 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |+
Line 509: Line 92:
! style="background: #F5F5F5; padding: 5px;" |[[Parvovirus|Parvovirus IgM antibody]]  
! style="background: #F5F5F5; padding: 5px;" |[[Parvovirus|Parvovirus IgM antibody]]  
! style="background: #F5F5F5; padding: 5px;" |Transient [[aplastic crisis]], [[Fetal]] [[infection]]
! style="background: #F5F5F5; padding: 5px;" |Transient [[aplastic crisis]], [[Fetal]] [[infection]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Fibromyalgia]]<ref name="pmid23213512">{{cite journal| author=Bellato E, Marini E, Castoldi F, Barbasetti N, Mattei L, Bonasia DE et al.| title=Fibromyalgia syndrome: etiology, pathogenesis, diagnosis, and treatment. | journal=Pain Res Treat | year= 2012 | volume= 2012 | issue=  | pages= 426130 | pmid=23213512 | doi=10.1155/2012/426130 | pmc=3503476 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23213512  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Maculopapular rash]]
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Mild [[inflammation]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings
! style="background: #F5F5F5; padding: 5px;" |[[Muscle pain]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Soft tissue abnormalities
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+/-
! style="background: #F5F5F5; padding: 5px;" |[[Maculopapular rash]]
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" |[[CRP]], [[Ca]]
! style="background: #F5F5F5; padding: 5px;" |Joint swelling
! style="background: #F5F5F5; padding: 5px;" |[[Synovial]] [[edema]] and thickness
! style="background: #F5F5F5; padding: 5px;" |Mild joint effusion in [[ultrasonography]]
! style="background: #F5F5F5; padding: 5px;" |Mild [[inflammation]]
! style="background: #F5F5F5; padding: 5px;" |Clinical findings
! style="background: #F5F5F5; padding: 5px;" |[[Mucositis]], [[Enthesitis]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hypothyroidism]]<ref name="pmid7740308">{{cite journal |vauthors=McLean RM, Podell DN |title=Bone and joint manifestations of hypothyroidism |journal=Semin. Arthritis Rheum. |volume=24 |issue=4 |pages=282–90 |date=February 1995 |pmid=7740308 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Dry and coarse [[skin]]
! style="background: #F5F5F5; padding: 5px;" |[[Anemia]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Clear yellow fluid with normal cell counts
! style="background: #F5F5F5; padding: 5px;" |[[TSH]], [[T4]], [[T3]]
! style="background: #F5F5F5; padding: 5px;" |Peri-[[articular]] demineralization
! style="background: #F5F5F5; padding: 5px;" |Destructive changes in the [[cartilage]] and [[bone]]
! style="background: #F5F5F5; padding: 5px;" |High-signal fluid in the [[joint]] space in [[MRI]]
! style="background: #F5F5F5; padding: 5px;" |[[Growth plate|Physeal growth plate]] with little evidence of [[cartilage]] cellular proliferation
! style="background: #F5F5F5; padding: 5px;" |[[TSH]], [[T4]], [[T3]]
! style="background: #F5F5F5; padding: 5px;" |Decreased [[Deep tendon reflex|DTR]], [[Fatigue]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Neuropathic pain]]<ref name="pmid23592730">{{cite journal |vauthors=Magrinelli F, Zanette G, Tamburin S |title=Neuropathic pain: diagnosis and treatment |journal=Pract Neurol |volume=13 |issue=5 |pages=292–307 |date=October 2013 |pmid=23592730 |doi=10.1136/practneurol-2013-000536 |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Livedo reticularis]]
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |[[Hyperglycemia]], [[Hypokalemia]], [[Hypocalcemia]]
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Neurologic]] examination
! style="background: #F5F5F5; padding: 5px;" |[[Paresthesia]], [[Dysesthesia]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |Metabolic bone disease<ref name="pmid17002489">{{cite journal |vauthors=Skowrońska-Jóźwiak E, Lorenc RS |title=Metabolic bone disease in children : etiology and treatment options |journal=Treat Endocrinol |volume=5 |issue=5 |pages=297–318 |date=2006 |pmid=17002489 |doi= |url=}}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Hyperpigmentation]]
! style="background: #F5F5F5; padding: 5px;" |Mild [[anemia]]
! style="background: #F5F5F5; padding: 5px;" |↑
! style="background: #F5F5F5; padding: 5px;" |Cell count < 25% [[PMNs]] (non-[[inflammatory]])
! style="background: #F5F5F5; padding: 5px;" |[[Vitamin D]], [[PTH]]
! style="background: #F5F5F5; padding: 5px;" |Peri-[[articular]] demineralization
! style="background: #F5F5F5; padding: 5px;" |[[Fracture|Microfractures]]
! style="background: #F5F5F5; padding: 5px;" |[[Subperiosteal|Subperiosteal reaction]]
! style="background: #F5F5F5; padding: 5px;" |Decrease [[mineralization]] of [[bone matrix]]
! style="background: #F5F5F5; padding: 5px;" |Laboratory findings
! style="background: #F5F5F5; padding: 5px;" |[[Bone pain]], [[Constipation]]
|-
! colspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Depression]]<ref name="pmid16001092">{{cite journal| author=Trivedi MH| title=The link between depression and physical symptoms. | journal=Prim Care Companion J Clin Psychiatry | year= 2004 | volume= 6 | issue= Suppl 1 | pages= 12-6 | pmid=16001092 | doi= | pmc=486942 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16001092  }}</ref>
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |+
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |Normal
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |-
! style="background: #F5F5F5; padding: 5px;" |[[Psychological analysis|Psychological interview]]
! style="background: #F5F5F5; padding: 5px;" |[[Psychomotor retardation|Slow psychomotor]], [[Muscle pain]]
|-
|-
|}
|}
</small>
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 15:18, 3 May 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Joint Swelling Fever Weight loss Claudication Morning stiffness Local erythema Skin manifestation CBC ESR Synovial fluid Other X-ray CT scan Other
Polyarthritis Infectious arthritis Lyme disease[1] + + +/- +/- - - Erythema migrans Leukopenia, Thrombocytopenia - Cell counts 500-98,000/µL Microscopic hematuria, Proteinuria, ↑ALT or AST - - - Fibrosis of the deeper dermis and hyalinization of collagen bundles Serologic tests Erythema migrans
Bacterial endocarditis[2] + + + - - +/- Janeway lesions, Osler nodes, Roth spots Normochromic-normocytic anemia ↑ ↑WBC, S. aureus in culture Hyperglobulinemia, Cryoglobulinemia Joint erosion and effusion - - Vegetation or intracardiac abscess demonstrating active endocarditis Echocardiography (TTE) Vertebral osteomyelitis
Polyarticular pain Viral arthritis Parvovirus[3] + + +/- - - - Fifth disease/ Erythema infectiosum Aplastic crisis ↑ Normal ANA, RF, CRP Joint swelling - - Immune complex deposition Parvovirus IgM antibody Transient aplastic crisis, Fetal infection

References

  1. ↑ Lantos PM (2015). "Chronic Lyme disease". Infect Dis Clin North Am. 29 (2): 325–40. doi:10.1016/j.idc.2015.02.006. PMC 4477530. PMID 25999227.
  2. ↑ Soor P, Sharma N, Rao C (2017). "Multifocal Septic Arthritis Secondary to Infective Endocarditis: A Rare Case Report". J Orthop Case Rep. 7 (1): 65–68. doi:10.13107/jocr.2250-0685.692. PMC 5458702. PMID 28630844.
  3. ↑ Moore TL (July 2000). "Parvovirus-associated arthritis". Curr Opin Rheumatol. 12 (4): 289–94. PMID 10910181.
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