Methemoglobinemia classification: Difference between revisions
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==Classification== | ==Classification== | ||
'''Congenital (Hereditary) Methemoglobinemia''' | '''Congenital (Hereditary) Methemoglobinemia''' | ||
There are three main congenital conditions that lead to methemoglobinemia: | *There are three main congenital conditions that lead to methemoglobinemia: | ||
1. [[Cytochrome b5 reductase deficiency]] and [[pyruvate kinase deficiency]] | 1. [[Cytochrome b5 reductase deficiency]] and [[pyruvate kinase deficiency]]<ref>{{Haematologia (Budap). 1982 Dec;15(4):389-99. Enzymopenic hereditary methemoglobinemia. Jaffé ER. pmid=PMID: 6764628}}</ref> | ||
2. [[G6PD deficiency]] | 2. [[G6PD deficiency]] | ||
3. Presence of | 3. Presence of [[abnormal hemoglobin]] ([[Hb M]]) | ||
'''Acquired or Acute Methemoglobinemia''' | '''Acquired or Acute Methemoglobinemia''' | ||
The most common causes are different [[oxidant drugs]], [[toxins]] and [[chemicals]]. | *The most common causes are different [[oxidant drugs]], [[toxins]] and [[chemicals]].<ref>{{Med Toxicol. 1986 Jul-Aug;1(4):253-60. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Hall AH, Kulig KW, Rumack BH.pmid=PMID: 3537620}}</ref> | ||
==References== | ==References== | ||
Revision as of 12:35, 15 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Template:Aksiniya K. Stevasarova, M.D.
Overview
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia.
Classification
Congenital (Hereditary) Methemoglobinemia
- There are three main congenital conditions that lead to methemoglobinemia:
1. Cytochrome b5 reductase deficiency and pyruvate kinase deficiency[1]
3. Presence of abnormal hemoglobin (Hb M)
Acquired or Acute Methemoglobinemia
- The most common causes are different oxidant drugs, toxins and chemicals.[2]
References
- ↑ Template:Haematologia (Budap). 1982 Dec;15(4):389-99. Enzymopenic hereditary methemoglobinemia. Jaffé ER. pmid=PMID: 6764628
- ↑ Template:Med Toxicol. 1986 Jul-Aug;1(4):253-60. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Hall AH, Kulig KW, Rumack BH.pmid=PMID: 3537620