Folate deficiency screening: Difference between revisions
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==Screening== | ==Screening== | ||
Screening for folate deficiency is not routinely recommended. However, early detection can lead to folic acid supplementation, which is a simple treatment of the underlying cause. can reduce the risk of anemia certain conditions such as fetal neural tube defects in newborns. | |||
===High risk populations=== | |||
*Older people (Age >65) | |||
*Alcohol abusers | |||
*Pregnant or lactating women | |||
*Preterm infants | |||
*Lower socioeconomic groups | |||
*Patients with intestinal malabsorption | |||
*Patients with conditions with increased cell turnover states | |||
*Patients on special diets, and infants given goats' milk | |||
*Chronic dialysis patients. | |||
===Screening tests=== | |||
CBC may show increased MCV i.e. MCV > 100fL with or without low hemoglobin.Further testing includes serum folate level (Adults: 2-20 ng/mL). High risk populations are tested for folate deficiency if their CBC is abnormal. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 19:29, 20 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Screening
Screening for folate deficiency is not routinely recommended. However, early detection can lead to folic acid supplementation, which is a simple treatment of the underlying cause. can reduce the risk of anemia certain conditions such as fetal neural tube defects in newborns.
High risk populations
- Older people (Age >65)
- Alcohol abusers
- Pregnant or lactating women
- Preterm infants
- Lower socioeconomic groups
- Patients with intestinal malabsorption
- Patients with conditions with increased cell turnover states
- Patients on special diets, and infants given goats' milk
- Chronic dialysis patients.
Screening tests
CBC may show increased MCV i.e. MCV > 100fL with or without low hemoglobin.Further testing includes serum folate level (Adults: 2-20 ng/mL). High risk populations are tested for folate deficiency if their CBC is abnormal.