Hyponatremia overview: Difference between revisions
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==Classification== | ==Classification== | ||
Hyponatremia ([[serum]] [[sodium]] less than 135 mEq/L) may be classified based upon [[serum]] [[ADH]] level, duration of hyponatremia, [[serum]] [[osmolality]] and volume status. The various classification systems enable accurate identification of the cause of hyponatremia and hence translate into optimal management based on the condition of the patient. | |||
==Pathophysiology== | ==Pathophysiology== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
In 1858, Claude Bernard, French physiologist first proposed a direct relationship between the central nervous system and renal excretion of osmotically active solutes. In 1913, Jungmann and Meyer in Germany induced polyuria and increased urinary salt excretion in animals through medullary lesion. In 1950, Peters, Welt, and co-workers described few patients with encephalitis, hypertensive intracranial hemorrhage, and bulbar poliomyelitis who presented with severe dehydration and hyponatremia.
Classification
Hyponatremia (serum sodium less than 135 mEq/L) may be classified based upon serum ADH level, duration of hyponatremia, serum osmolality and volume status. The various classification systems enable accurate identification of the cause of hyponatremia and hence translate into optimal management based on the condition of the patient.