Leiomyosarcoma other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Despite the advances in radiology, it is still hard to differentiate leiomyosarcoma from other unusual malignant tumors prior to the surgeries.

Biopsy

• Biopsy: It is the most important test for diagnosing leiomyosarcoma. During this peroid, the doctors remove a small amount of tissue for examination under a microscope. Then the pathologists may analyze the samples and tell whether the tissues is benign or cancerous.

• Endoscopy and biopsy: It is the main test used to diagnose gastrointestinal tract leiomyosarcoma when patient's signs and symptoms suggest this disease may be present. After you are sedated, the doctor puts an endoscope which is a thin, flexible, lighted tube down your throat. Then the doctor can view the lining of your esophagus, stomach, and first part of the small intestine. If abnormal areas are noted, biopsies can be obtained through the endoscope. The tissue samples will be checked by the pathologists under a microscope to see whether sarcoma is present or not.

• Hysteroscopy and endometrial biopsy: This is the most important test used to diagnose uterine leiomyosarcoma when signs and symptoms suggest this disease may be present. The gynecologist inserts a tiny telescope into the uterus through the cervixan and obtains abnormal samples. The tissue samples will be checked by pathologists under a microscope to see whether sarcoma is present or not.