Focal segmental glomerulosclerosis causes: Difference between revisions
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==Causes== | ==Causes== | ||
The following list shows all the causes of FSGS<ref name="pmid23871408">{{cite journal| author=Beck L, Bomback AS, Choi MJ, Holzman LB, Langford C, Mariani LH et al.| title=KDOQI US commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis. | journal=Am J Kidney Dis | year= 2013 | volume= 62 | issue= 3 | pages= 403-41 | pmid=23871408 | doi=10.1053/j.ajkd.2013.06.002 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23871408 }} </ref>: | The following list shows all the causes of FSGS<ref name="pmid23871408">{{cite journal| author=Beck L, Bomback AS, Choi MJ, Holzman LB, Langford C, Mariani LH et al.| title=KDOQI US commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis. | journal=Am J Kidney Dis | year= 2013 | volume= 62 | issue= 3 | pages= 403-41 | pmid=23871408 | doi=10.1053/j.ajkd.2013.06.002 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23871408 }} </ref>: | ||
===Primary (Idiopathic) FSGS=== | ===Primary (Idiopathic) FSGS=== | ||
Revision as of 19:09, 31 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Causes
The following list shows all the causes of FSGS[1]:
Primary (Idiopathic) FSGS
Secondary FSGS
Familial
- Mutations in alpha actinin 4
- Mutations in NPHS1 (nephrin)
- Mutations in NPHS2 (podocin)
- Mutations in WT-1
- Mutations in TRPC6
- Mutations in SCARB2 (LIMP2)
- Mutations in INF2 (formin)
- Mutations in CD2-associated protein
- Mitochondrial cytopathies
Virus Associated
Medication
- Heroin
- Interferon alpha
- Lithium
- Pamidronate/aledronate
- Anabolic steroids
Adaptive Structural-Functional Responses
Reduced Kidney Size
- Oligomeganephronia
- Unilateral kidney agenesis
- Kidney dysplasia
- Cortical necrosis
- Reflux nephropathy
- Surgical kidney ablation
- Chronic allograft nephropathy
- Any advanced kidney disease with reduction in functioning nephrons
Initially Normal Kidney Mass
Malignancy
Nonspecific Pattern of FSGS Caused by Kidney Scarring in Glomerular Disease
- Focal proliferative glomerulonephritis
- IgA nephropathy
- Lupus nephritis
- Pauci-immune focal necrotizing and crescentic glomerulonephritis
- Alport's syndrome (hereditary nephritis)
- Membranous nephropathy
- Thrombotic microangiopathy
References
- ↑ Beck L, Bomback AS, Choi MJ, Holzman LB, Langford C, Mariani LH; et al. (2013). "KDOQI US commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis". Am J Kidney Dis. 62 (3): 403–41. doi:10.1053/j.ajkd.2013.06.002. PMID 23871408.