Fanconi syndrome causes: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Vahid (talk | contribs)
nocaptcha
274 edits
Vahid (talk | contribs)
nocaptcha
274 edits
Line 9: Line 9:
** ''Accumulation of a toxic substance''  (e.g. Cystinosis, Tyrozinemia, Lysinuric Protein Intolerance, Glycogen Storage Diseases, Galactosemia, wilson, fructose intolerance)
** ''Accumulation of a toxic substance''  (e.g. Cystinosis, Tyrozinemia, Lysinuric Protein Intolerance, Glycogen Storage Diseases, Galactosemia, wilson, fructose intolerance)
** ''Energy provision failure'' (e.g. Mitochondriopathies)   
** ''Energy provision failure'' (e.g. Mitochondriopathies)   
** ''Disruption of endocytosis and intra-cellular transport'' (e.g. ARC syndrome, Lowe syndrome and Dent disease).
** ''Disruption of endocytosis and intra-cellular transport mechanisms'' (e.g. ARC syndrome, Lowe syndrome and Dent disease).
* '''Environmental causes''' (e.g. Heavy metals exposure, Drugs, Chemotherapy)
* '''Exogenous causes''' (e.g. Heavy metals exposure, Drugs, Chemotherapy)
* '''Acquired causes''' (e.g. Multiple myeloma, Amyloidosis, Paroxysmal nocturnal hemoglobinuria)
* '''Acquired causes''' (e.g. Multiple myeloma, Amyloidosis, Paroxysmal nocturnal hemoglobinuria)


Line 20: Line 20:
** Tyrozinemia  
** Tyrozinemia  
** Lysinuric Protein Intolerance  
** Lysinuric Protein Intolerance  
** Glycogen Storage Diseases
** Glycogen Storage Disease type I
** Galactosemia
** Galactosemia
** Wilson
** Wilson
** Fructose intolerance
** Fructose intolerance
** Fanconi-Bickel syndrome
* '''Energy provision failure'''
** Mitochondriopathies
* '''Disruption of endocytosis and intra-cellular transport'''
** Lowe syndrome 
** NaPi-IIa gene mutation
** EHHADH gene mutations
** Dent disease


=== '''Environmental causes''' ===
=== '''Exogenous causes''' ===
* Nephrotic syndrome
* Multiple myeloma
* Sjögren syndrome
* Renal transplantation
* Acute tubulointerstitial nephritis with uveitis (TINU) syndrome
* Autoimmune interstitial nephritis and membranous nephropathy
* Anorexia nervosa
* Untreated condition of distal renal tubular acidosis
 
=== '''Acquired causes''' ===
* '''Drugs'''
* '''Drugs'''
** Anti-retroviral drugs
** Anti viral & Anti-retroviral drugs
*** ''Adefovir''
*** ''Adefovir''
*** ''Tenofovir''
*** ''Tenofovir''
*** ''Didanosine''
*** ''Didanosine''
*** ''Cidofovir''
*** ''Cidofovir''
*** ''Lamivudine''
*** ''Stavudine''


** Antibacterial Drugs
** Antibacterial Drugs
Line 49: Line 49:
** Anticonvulsants
** Anticonvulsants
*** ''Valproic acid''
*** ''Valproic acid''
* '''Heavy metals'''
* '''Heavy metals'''
** ''Lead''
** ''Lead''
** ''cadmium''
** ''cadmium''
** ''Mercury''
** ''Mercury''
** ''Copper''
* '''Chemotherapy'''
* '''Chemotherapy'''


** ''Alkylating and Platinating Agents''
** ''Alkylating & Platinating Agents''
*** ''Cisplatin''
*** ''Cisplatin''
*** ''Streptozocin''  
*** ''Streptozocin''  
*** ''Carboplatin''
*** ''Carboplatin''
*** ''Ifosfamide''
*** ''Ifosfamide''
*** ''Oxaplatin''
** ''Mercaptopurine''


** ''Mercaptopurine''.
=== '''Acquired causes''' ===
* ''Nephrotic syndrome''
* ''Multiple myeloma''
* Amyloidosis
* Paroxysmal nocturnal hemoglobinuria(PNH)
* ''Sjögren syndrome''
* ''Renal transplantation''
* ''Acute tubulointerstitial nephritis with uveitis (TINU) syndrome''
* ''Autoimmune interstitial nephritis and membranous nephropathy''
* ''Anorexia nervosa''
* ''Untreated condition of distal renal tubular acidosis''


===Less Common Causes===
===Less Common Causes===
Less common causes of [[disease name]] include:
Less common causes of Fanconi syndrome mostly found on case reports include:
*[Cause1]
*[Cause2]
*[Cause3]
 
===Genetic Causes===
*[Disease name] is caused by a mutation in the [gene name] gene.
 
===Causes by Organ System===


{| style="width:80%; height:100px" border="1"
*Other drugs such as: Fumaric Acid, Ranitidine, Salicylate, Methyl-3-Chromone in high doses and for long periods
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
*Chronic Alcohol abuse
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
*Crude Chinese herbal drugs (sometimes called Boui-ougi-tou)
|-
*L-Lysine
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
*Glue Sniffing
| bgcolor="Beige" | No underlying causes
*Autosomal dominant Fanconi syndrome with macrosomia and young onset diabetes mellitus
|-
*Arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome
|- bgcolor="LightSteelBlue"
*Idiopathic Fanconi syndrome
| '''Dental'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| bgcolor="Beige" | No underlying causes
|-
|}


===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
List the causes of the disease in alphabetical order.
List the causes of the disease in alphabetical order.
{{columns-list|3|
{{columns-list|3|
* Cause 1
*Adefovir
* Cause 2
*Aminoglycosides
* Cause 3
*Cidofovir
* Cause 4
*Cisplatin
* Cause 5
*Cystinosis
* Cause 6
*Dent disease
* Cause 7
*Didanosine
* Cause 8
*Drug-induced
* Cause 9
*Fanconi-Bickel syndrome
* Cause 10
*Galactosemia
*Glycogen Storage disease (type I)
*Hereditary fructose intolerance
*Ifosfamide
*Lamivudine
*Lowe’s syndrome
*Mitochondriopathies
*Oxaplatin
*Stavudine
*Streptozocin
*Tenofovir
*Tyrosinemia
*Valproic acid
*Wilson’s disease
*Tetracyclines
}}
}}


Revision as of 08:17, 5 June 2018


Fanconi syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Fanconi syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study Of Choice

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Fanconi syndrome causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Fanconi syndrome causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Fanconi syndrome causes

CDC on Fanconi syndrome causes

Fanconi syndrome causes in the news

Blogs on Fanconi syndrome causes

Directions to Hospitals Treating Fanconi syndrome

Risk calculators and risk factors for Fanconi syndrome causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Fanconi syndrome could be the result or complication of various causes affecting the normal function of Proximal convoluted tubule (PCT) ; in a simple and useful classification method, the causes could be classified as:

  • Genetic causes
    • Accumulation of a toxic substance (e.g. Cystinosis, Tyrozinemia, Lysinuric Protein Intolerance, Glycogen Storage Diseases, Galactosemia, wilson, fructose intolerance)
    • Energy provision failure (e.g. Mitochondriopathies)
    • Disruption of endocytosis and intra-cellular transport mechanisms (e.g. ARC syndrome, Lowe syndrome and Dent disease).
  • Exogenous causes (e.g. Heavy metals exposure, Drugs, Chemotherapy)
  • Acquired causes (e.g. Multiple myeloma, Amyloidosis, Paroxysmal nocturnal hemoglobinuria)

Causes

Genetic Causes

  • Accumulation of a toxic substance
    • Cystinosis
      • The most common inherited cause of Fanconi syndrome in children
    • Tyrozinemia
    • Lysinuric Protein Intolerance
    • Glycogen Storage Disease type I
    • Galactosemia
    • Wilson
    • Fructose intolerance
    • Fanconi-Bickel syndrome
  • Energy provision failure
    • Mitochondriopathies
  • Disruption of endocytosis and intra-cellular transport
    • Lowe syndrome
    • NaPi-IIa gene mutation
    • EHHADH gene mutations
    • Dent disease

Exogenous causes

  • Drugs
    • Anti viral & Anti-retroviral drugs
      • Adefovir
      • Tenofovir
      • Didanosine
      • Cidofovir
      • Lamivudine
      • Stavudine
    • Antibacterial Drugs
      • Tetracyclines
      • Aminoglycosides
    • Anticonvulsants
      • Valproic acid
  • Heavy metals
    • Lead
    • cadmium
    • Mercury
    • Copper
  • Chemotherapy
    • Alkylating & Platinating Agents
      • Cisplatin
      • Streptozocin
      • Carboplatin
      • Ifosfamide
      • Oxaplatin
    • Mercaptopurine

Acquired causes

  • Nephrotic syndrome
  • Multiple myeloma
  • Amyloidosis
  • Paroxysmal nocturnal hemoglobinuria(PNH)
  • Sjögren syndrome
  • Renal transplantation
  • Acute tubulointerstitial nephritis with uveitis (TINU) syndrome
  • Autoimmune interstitial nephritis and membranous nephropathy
  • Anorexia nervosa
  • Untreated condition of distal renal tubular acidosis

Less Common Causes

Less common causes of Fanconi syndrome mostly found on case reports include:

  • Other drugs such as: Fumaric Acid, Ranitidine, Salicylate, Methyl-3-Chromone in high doses and for long periods
  • Chronic Alcohol abuse
  • Crude Chinese herbal drugs (sometimes called Boui-ougi-tou)
  • L-Lysine
  • Glue Sniffing
  • Autosomal dominant Fanconi syndrome with macrosomia and young onset diabetes mellitus
  • Arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome
  • Idiopathic Fanconi syndrome

Causes in Alphabetical Order

List the causes of the disease in alphabetical order.

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Fanconi_syndrome_causes&oldid=1474681"